Amphetamine uses among truck drivers and comparison of urine amphetamine tests after oral administration
6
Issued Date
2023
Copyright Date
1992
Language
eng
File Type
application/pdf
No. of Pages/File Size
xii, 149 leaves
Access Rights
restricted access
Rights Holder(s)
Mahidol University
Bibliographic Citation
Thesis (M.Sc. (Toxicology))--Mahidol University, 1992
Suggested Citation
Jinda Tachasarin Amphetamine uses among truck drivers and comparison of urine amphetamine tests after oral administration. Thesis (M.Sc. (Toxicology))--Mahidol University, 1992. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/90601
Title
Amphetamine uses among truck drivers and comparison of urine amphetamine tests after oral administration
Alternative Title(s)
การใช้ยาม้าในคนขับรถบรรทุกและการศึกษาเปรียบเทียบการตรวจหาแอมเฟตตามีนในปัสสาวะของอาสาสมัครที่ได้รับยาชนิดต่าง ๆ
Author(s)
Abstract
This research was conducted to study the use of amphetamine among the truck drivers and the comparison of methods used to test for amphetamine tests in the urine of volunteers who had taken different of drugs. The study was divided into two parts. The first part, 245 truck drivers from different regions were interviewed. 82% replied that they have used amphetamine. Only 56.70%believed amphetamine was an addicting agent and they used it only while driving. The quantity used was half a tablet (x=0.47). They paid 15-25 Baht per tablet. Furthermore, various factors related to the use of amphetamine were analyzed. It was found that the driving distance the driving time, income,(number of trips),the knowledge and attitudes about amphetamine were significantly related to the use of amphetamine among truck drivers (P-valve <0.05). The stepwise multiple regression showed that attitudes about amphetamine and free to sleep were two unrelated factor that could explain the regression of the use of amphetamine, most at f = 19.00 and 15.00 respectively. The second part is a comparative study of methods used for amphetamine tests in the urine among volunteers who have taken various types of medicines including amphetamine and not including amphetamine. The check up was conducted by three Methods: ONTRACK, TDX and COLOR TEST. It was found that ONTRAK gave positive result only for amphetamine. TDX gave positive result for both amphetamine, methamphetamine and other medicines not including amphetamine such as was Ponderal(R). COLOR TEST gave positive result for amphetamine, methamphetamine and cold relief medicine such as maxiphed(R) (pseudoephedrine). From this study, it was possible to find out the positive predictive value of TDX, COLOR TEST and ONTRAK as follow: TestTDX Color test Ontrak Positive predictive value 100% 64% 100% Negative predictive value 87% 21% 67% Sensitivity 95% 14% 38% Specificity 100% 75% 100% Accuracy 96% 28% 33% Moreover, it was found that coffee and drinks containing caffeine gave negative result by the three test methods. Furthermore, the study of water loading and urinary alkalinization did not show any significant differences (P-value <0.05). Thus, the methods of testing amphetamine in the urine should be further studied.
Degree Name
Master of Science
Degree Level
Master's degree
Degree Department
Faculty of Science
Degree Discipline
Toxicology
Degree Grantor(s)
Mahidol University