Perceived COVID-19 vaccine effectiveness, acceptance, and drivers of vaccination decision-making among the general adult population: A global survey of 20 countries
Issued Date
2022-01-01
Resource Type
ISSN
19352727
eISSN
19352735
Scopus ID
2-s2.0-85123815082
Pubmed ID
35089917
Journal Title
PLoS Neglected Tropical Diseases
Volume
16
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
PLoS Neglected Tropical Diseases Vol.16 No.1 (2022)
Suggested Citation
Marzo R.R. Perceived COVID-19 vaccine effectiveness, acceptance, and drivers of vaccination decision-making among the general adult population: A global survey of 20 countries. PLoS Neglected Tropical Diseases Vol.16 No.1 (2022). doi:10.1371/journal.pntd.0010103 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86681
Title
Perceived COVID-19 vaccine effectiveness, acceptance, and drivers of vaccination decision-making among the general adult population: A global survey of 20 countries
Author(s)
Author's Affiliation
KHANA
Sukkur IBA University
Sunshine Coast Hospital and Health Service
Leibniz Institute for Prevention Research and Epidemiology
Universitas Islam Bandung
International University,Vietnam National University Ho Chi Minh City
Management & Science University, Malaysia
Viet Nam National University Ho Chi Minh City
Universiti Malaysia Terengganu
Kabul University
Salahaddin University-Erbil
University of the Sunshine Coast
King Faisal University
Jahangirnagar University
Touro University California
Fachhochschule St. Polten
University of Southampton, Faculty of Medicine
Himalayan Institute of Medical Sciences
Gazi University, Faculty of Medicine
Monash University Malaysia
National University of Singapore
Manipal Academy of Higher Education
Eastern Illinois University
Mahidol University
Bangkok University
IMC Fachhochschule Krems GmbH
Ahmadu Bello University
Fujian Medical University
University of Oxford Medical Sciences Division
Dhurakij Pundit University
Clinical Research Key (CRK-CRO)
Saint Alexius College
Medical Agency for Research and Statistics
University for Continuing Education Krems
Centre for Advanced Research Excellence in Public Health
Asia Metropolitan University
San Pedro College
Sukkur IBA University
Sunshine Coast Hospital and Health Service
Leibniz Institute for Prevention Research and Epidemiology
Universitas Islam Bandung
International University,Vietnam National University Ho Chi Minh City
Management & Science University, Malaysia
Viet Nam National University Ho Chi Minh City
Universiti Malaysia Terengganu
Kabul University
Salahaddin University-Erbil
University of the Sunshine Coast
King Faisal University
Jahangirnagar University
Touro University California
Fachhochschule St. Polten
University of Southampton, Faculty of Medicine
Himalayan Institute of Medical Sciences
Gazi University, Faculty of Medicine
Monash University Malaysia
National University of Singapore
Manipal Academy of Higher Education
Eastern Illinois University
Mahidol University
Bangkok University
IMC Fachhochschule Krems GmbH
Ahmadu Bello University
Fujian Medical University
University of Oxford Medical Sciences Division
Dhurakij Pundit University
Clinical Research Key (CRK-CRO)
Saint Alexius College
Medical Agency for Research and Statistics
University for Continuing Education Krems
Centre for Advanced Research Excellence in Public Health
Asia Metropolitan University
San Pedro College
Other Contributor(s)
Abstract
Background Mass vaccination campaigns have significantly reduced the COVID-19 burden. However, vaccine hesitancy has posed significant global concerns. The purpose of this study was to determine the characteristics that influence perceptions of COVID-19 vaccine efficacy, acceptability, hesitancy and decision making to take vaccine among general adult populations in a variety of socioeconomic and cultural contexts. Methods Using a snowball sampling approach, we conducted an online cross-sectional study in 20 countries across four continents from February to May 2021. Results A total of 10,477 participants were included in the analyses with a mean age of 36±14.3 years. The findings revealed the prevalence of perceptions towards COVID-19 vaccine’s effectiveness (78.8%), acceptance (81.8%), hesitancy (47.2%), and drivers of vaccination decision-making (convenience [73.3%], health providers’ advice [81.8%], and costs [57.0%]). The county-wise distribution included effectiveness (67.8–95.9%; 67.8% in Egypt to 95.9% in Malaysia), acceptance (64.7–96.0%; 64.7% in Australia to 96.0% in Malaysia), hesitancy (31.5–86.0%; 31.5% in Egypt to 86.0% in Vietnam), convenience (49.7–95.7%; 49.7% in Austria to 95.7% in Malaysia), advice (66.1–97.3%; 66.1% in Austria to 97.3% in Malaysia), and costs (16.0–91.3%; 16.0% in Vietnam to 91.3% in Malaysia). In multivariable regression analysis, several socio-demographic characteristics were identified as associated factors of outcome variables including, i) vaccine effectiveness: younger age, male, urban residence, higher education, and higher income; ii) acceptance: younger age, male, urban residence, higher education, married, and higher income; and iii) hesitancy: male, higher education, employed, unmarried, and lower income. Likewise, the factors associated with vaccination decision-making including i) convenience: younger age, urban residence, higher education, married, and lower income; ii) advice: younger age, urban residence, higher education, unemployed/student, married, and medium income; and iii) costs: younger age, higher education, unemployed/student, and lower income. Conclusions Most participants believed that vaccination would effectively control and prevent COVID-19, and they would take vaccinations upon availability. Determinant factors found in this study are critical and should be considered as essential elements in developing COVID-19 vaccination campaigns to boost vaccination uptake in the populations.