Acetylcholinesterase and cholinesterase activities in rats infected with giardia lamblia
Issued Date
2004
Resource Type
Language
eng
Rights
Mahidol University
Suggested Citation
Cheeraratana Cheeramakara, จีระรัตน์ จีระมะกร, Apichart Nontprasert, อภิชาต นนท์ประเสริฐ, Wanyarat Thanomsak, วัลยารัตน์ ถนอมศักดิ์, Kriyaporn Songmeang, กริยาพร สองเมือง, Nopachai Suthisai, นภชัย สุทธิสัย, Bangorn Sukchut, Suvit Areekul, สุวิทย์ อารีย์กูล (2004). Acetylcholinesterase and cholinesterase activities in rats infected with giardia lamblia. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/63354
Title
Acetylcholinesterase and cholinesterase activities in rats infected with giardia lamblia
Abstract
Thirty-three adult Wistar rats were assigned randomly to receive either 1.0 x 106 human Giardia lamblia cysts (n = 18) or controls (n = 15). Actylcholinesterase (AChE) and cholinesterase (ChE) activities in the infected rats were compared with the controls. The results showed that the plasma ChE activities in the infected rats were statistically significant higher than controls on day 10, 25, 29, 33, and 40 post-infection and decreased to baseline after day 49 post-infection. The red cell AChE activities in the infected rats were higher than the controls on day 37, 55, and 58 post-infection. There was a reverse correlation between Giardia cysts output and red cell AChE activity in the infected rats. This study suggested that there was no liver involvement but enhancement of erythropoiesis secondary to anemia in rats infected with Giardia lamblia.
Description
Joint International Tropical Medicine Meeting 2004: Ambassador Hotel, Thailand 29 November-1 December 2004: abstract. Bangkok: Faculty of Tropical Medicine, Mahidol University; 2004. p.216.