Inactivation kinetic parameters of hydrogen peroxide application in commercial sterility of aseptic processing systems
Issued Date
2024-10-01
Resource Type
ISSN
02608774
Scopus ID
2-s2.0-85191291212
Journal Title
Journal of Food Engineering
Volume
378
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Food Engineering Vol.378 (2024)
Suggested Citation
Sawale M., Singh A., Benyathiar P., Ozadali F., Bhunia A.K., Pol V.G., Mishra D.K. Inactivation kinetic parameters of hydrogen peroxide application in commercial sterility of aseptic processing systems. Journal of Food Engineering Vol.378 (2024). doi:10.1016/j.jfoodeng.2024.112105 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/98198
Title
Inactivation kinetic parameters of hydrogen peroxide application in commercial sterility of aseptic processing systems
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Hydrogen peroxide (H2O2) is a commonly used sterilant for aseptic processing and packaging systems. Surrogate bacterial spores are commonly used for the microbiological validation of the sterilization process. However, limited information is available on the resistance of these surrogate spores in liquid H2O2 (LHP) and vapor H2O2 (VHP). This study aims to fill the gaps in understanding of microbial inactivation parameters and the impact of temperature on VHP effectiveness. 35 % LHP experiments were conducted at temperatures ranging from 25 to 70 °C, while VHP tests were performed using vaporized sterilant technology (VST) and temperatures ranging from 43.3 to 60 °C. Exposure times ranged from 1 to 18 s, and VHP concentrations of 2500 and 4450 PPM were used while maintaining a relative humidity of 0.5%. The model performance of the log-linear and Weibull model was assessed using Root Mean Square Error (RMSE), the sum of the square, and Akaike Information Criterion (AIC) scores. The Weibull model outperformed the log-linear model in terms of parameter estimation and statistical indices.