Low-Grade Adenosquamous Carcinoma of the Breast Masquerading as a Fibroepithelial Lesion on Core Biopsy: A Challenging Case
Issued Date
2024-12-01
Resource Type
ISSN
10152008
eISSN
14230291
Scopus ID
2-s2.0-85211447937
Pubmed ID
38952139
Journal Title
Pathobiology
Volume
91
Issue
6
Start Page
455
End Page
462
Rights Holder(s)
SCOPUS
Bibliographic Citation
Pathobiology Vol.91 No.6 (2024) , 455-462
Suggested Citation
Laokulrath N., Chuwa E., Gudi M., Tan P.H. Low-Grade Adenosquamous Carcinoma of the Breast Masquerading as a Fibroepithelial Lesion on Core Biopsy: A Challenging Case. Pathobiology Vol.91 No.6 (2024) , 455-462. 462. doi:10.1159/000540029 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/102419
Title
Low-Grade Adenosquamous Carcinoma of the Breast Masquerading as a Fibroepithelial Lesion on Core Biopsy: A Challenging Case
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Corresponding Author(s)
Other Contributor(s)
Abstract
Introduction: Diagnosing low-grade adenosquamous carcinoma (LGASC) presents significant challenges due to its subtle morphology, variable immunohistochemical expression, and resemblance to benign lesions like radial scar and complex sclerosing lesions. Case Presentation: We present a case of a 53-year-old woman with a subareolar mass initially thought to be a fibroepithelial neoplasm on core biopsy. Subsequent wide excision revealed LGASC with oestrogen receptor expression (weak to moderate intensity, 40% of tumour cells). Conclusion: These findings, rarely reported, highlight the difficulty of diagnosing LGASC on small tissue samples.