History of Changes in the Protocol of Clinical Trial of Zinc Supplementation in Treatment of COVID-19 by Hydroxychloroquine

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dc.contributor.authorSornsil D.
dc.contributor.authorHarada K.H.
dc.contributor.authorPhosri A.
dc.contributor.otherMahidol University
dc.date.accessioned2023-08-28T18:01:16Z
dc.date.available2023-08-28T18:01:16Z
dc.date.issued2023-01-01
dc.description.abstractAn article published in this journal used a randomized controlled trial to evaluate the efficacy of combining chloroquine/hydroxychloroquine (CQ/HCQ) and zinc in the treatment of COVID-19 patients. Findings from this study indicate that zinc supplements did not enhance the clinical efficacy of hydroxychloroquine in improving COVID-19 treatment. Although this finding is consistent with many previous studies, several concerns regarding study protocol and trial registration, including interventions and primary outcomes, have been raised in which the protocol has been changed after the completion of the recruitment.
dc.identifier.citationBiological Trace Element Research (2023)
dc.identifier.doi10.1007/s12011-023-03807-9
dc.identifier.eissn15590720
dc.identifier.issn01634984
dc.identifier.pmid37572184
dc.identifier.scopus2-s2.0-85167822258
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/88833
dc.rights.holderSCOPUS
dc.subjectBiochemistry, Genetics and Molecular Biology
dc.titleHistory of Changes in the Protocol of Clinical Trial of Zinc Supplementation in Treatment of COVID-19 by Hydroxychloroquine
dc.typeArticle
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85167822258&origin=inward
oaire.citation.titleBiological Trace Element Research
oairecerif.author.affiliationGraduate School of Medicine
oairecerif.author.affiliationMahidol University

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