A comparison of the effect of procedural pain on cerebral oxygen saturation between late preterm and term infants
Issued Date
2024-01-01
Resource Type
ISSN
07438346
eISSN
14765543
Scopus ID
2-s2.0-85194241756
Pubmed ID
38789794
Journal Title
Journal of Perinatology
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Perinatology (2024)
Suggested Citation
Amornjiraporn I., Rugsapol S., Thanasarnpaiboon P., Paes B., Kitsommart R. A comparison of the effect of procedural pain on cerebral oxygen saturation between late preterm and term infants. Journal of Perinatology (2024). doi:10.1038/s41372-024-01978-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/98590
Title
A comparison of the effect of procedural pain on cerebral oxygen saturation between late preterm and term infants
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Abstract
Objectives: We prospectively compared cerebral oxygen saturation (CrSO2) and pain score changes during procedures in late preterm (LPT) versus term infants. Methods: Near-infrared spectroscopy, pulse oximetry, Neonatal Infant Pain Scale (NIPS) and Premature Infant Pain Profile-Revised (PIPP-R) scores were assessed and CrSO2 data analyzed. Results: Thirty infants in each group were evaluated. LPT infants displayed a milder significant drop in Minimum post-procedural CrSO2 and smaller Maximum-Minimum post-procedural CrSO2 disparity. CrSO2 minute changes between the groups were non-significant. Moderate correlations were observed in both groups between NIPS and Minimum post-procedural CrSO2, and a moderate correlation was found in the Maximum-Minimum post-procedural CrSO2 difference in LPT infants. No correlation between PIPP-R and CrSO2 values was noted. Conclusion: LPT and term infants demonstrated decreased CrSO2 in response to painful procedures. Correlations between CrSO2 and PIPP-R or NIPS scores were poor to moderate, reflecting the complex nature of these associations relative to gestational age.