Radical initiated fragmentation and cyclization reactions
3
Issued Date
2024
Copyright Date
1991
Resource Type
Language
eng
File Type
application/pdf
No. of Pages/File Size
iv, 141 leaves : ill.
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
Mahidol University
Bibliographic Citation
Thesis (M.Sc. (Organic Chemistry))--Mahidol University, 1991
Suggested Citation
Pornpun Rattananakin Radical initiated fragmentation and cyclization reactions. Thesis (M.Sc. (Organic Chemistry))--Mahidol University, 1991. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/100132
Title
Radical initiated fragmentation and cyclization reactions
Alternative Title(s)
ปฏิกิริยาการเปิดและปิดวงแหวนโดยเริ่มจากแรดิคัล
Author(s)
Advisor(s)
Abstract
Fragmentation of α-halosulfonyl cycloalkanol via radical were investigated. Three different reagents were employed i.e.: 1. α-Sulfonyl cyclobutyl carbinyl radicals could be generated by Tri-n -butyltin hydride (TBTH)/AIBN/benzene to give the fragmentation products and the radical formed by fragmentation could be trapped with acrylonitrile. 2. Alkoxy radicals could be generated by [bis(trifluoroacetoxy)iodo]benzene (BTFIB)/I(,2) or (diacetoxyiodo)benzene (DAIB)/I(,2) to give the fragmentation products or undergo intramolecular cyclization on olefinic side chains to give cyclic ethers. These reactions are useful synthetically for the preparation of highly functionalized acyclic intermediates and cyclic ether (Schemes A and B).
Description
Organic Chemistry (Mahidol University 1991)
Degree Name
Master of Science
Degree Level
Master's degree
Degree Department
Faculty of Science
Degree Discipline
Organic Chemistry
Degree Grantor(s)
Mahidol University