Efficacy of adding an interspace block to the posterior knee for perioperative pain in total knee arthroplasty: a randomized controlled trial
Issued Date
2022-01-01
Resource Type
ISSN
17453674
eISSN
17453682
Scopus ID
2-s2.0-85143064252
Pubmed ID
36448721
Journal Title
Acta Orthopaedica
Volume
93
Start Page
894
End Page
900
Rights Holder(s)
SCOPUS
Bibliographic Citation
Acta Orthopaedica Vol.93 (2022) , 894-900
Suggested Citation
Chatmaitri S. Efficacy of adding an interspace block to the posterior knee for perioperative pain in total knee arthroplasty: a randomized controlled trial. Acta Orthopaedica Vol.93 (2022) , 894-900. 900. doi:10.2340/17453674.2022.5257 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/87402
Title
Efficacy of adding an interspace block to the posterior knee for perioperative pain in total knee arthroplasty: a randomized controlled trial
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
Background and purpose — The interspace between the popliteal artery and the capsule of the posterior knee (IPACK) block is a novel anesthetic technique for total knee arthroplasty (TKA). Our objective was to compare the effect of IPACK and adductor canal block (ACB) and periarticular injection (PAI), relative to ACB and PAI only, from baseline to postoperative day 3, in patients undergoing unilateral primary TKA. Patients and methods — This was a single-center, double-blinded, randomized controlled trial. Adults over the age of 50 who were scheduled for unilateral primary TKA were enrolled. They were randomly assigned to ACB and PAI block (control group), or ACB, PAI, and IPACK block (IPACK group). The primary outcome was mean pain at rest during 24–48 hours post-operation using a numerical rating scale (0–10). We also investigated opioid use and ambulation pain. Results — 89 patients were evaluated, 45 from the control group and 44 from the IPACK group. Despite slightly higher mean pain score at rest in the control group, no sta-tistically significant difference was found during 0–24 hours (0.13; 95% CI –0.19 to 0.46), 24–48 hours (0.42; CI –0.06 to 0.89), and 48–72 hours (0.35; CI 0.00 to 0.69) postopera-tively as well as in maximum pain scores at rest. Neither pain during ambulation nor the number of opioids used differed between the trial groups at any given time point. Conclusion — The addition of the IPACK block to ACB and PAI did not reduce postoperative pain intensity or opioid usage. Therefore, IPACK block may not offer any benefit for pain management in patients undergoing unilateral primary TKA who are already receiving ACB and PAI.