Cognitive dysfunction in older patients undergoing non-neurosurgery in the immediate postoperative period: A systematic review
Issued Date
2024-08-01
Resource Type
eISSN
20541058
Scopus ID
2-s2.0-85202074167
Journal Title
Nursing Open
Volume
11
Issue
8
Rights Holder(s)
SCOPUS
Bibliographic Citation
Nursing Open Vol.11 No.8 (2024)
Suggested Citation
Kitthanyateerakul P., Tankumpuan T., Davidson P.M. Cognitive dysfunction in older patients undergoing non-neurosurgery in the immediate postoperative period: A systematic review. Nursing Open Vol.11 No.8 (2024). doi:10.1002/nop2.70023 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/100645
Title
Cognitive dysfunction in older patients undergoing non-neurosurgery in the immediate postoperative period: A systematic review
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Author's Affiliation
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Abstract
Aim: To explore the risk factors associated with postoperative cognitive dysfunction in older patients within the first 7 days after non-neurosurgical surgery and anaesthesia. Design: A systematic review. Methods: Following, PRISMA 2020 (Preferred Reporting Items for Systematic Reviews and Meta-analyses). Checklist, a systematic review of studies published from January 2018 to January 2024. The literature search was conducted across six electronic online databases, including PubMed, EMBASE, Scopus, Ovid, MEDLINE and Science Direct, and the Johns Hopkins Nursing Evidence-Based Practice Evidence Rating Scale was used for study appraisal. Results: The initial search yielded 1750 studies. The review included 19 studies which comprised prospective observational, case–control and retrospective studies. The prevalence of postoperative cognitive dysfunction ranged from 19% to 64% among older adults undergoing non-neurosurgery. The identified risk factors were classified into three phases including preoperative, intraoperative and postoperative. Preoperative risk factors were found in age, educational attainment, malnutrition, preoperative biomarkers and co-morbidities. Intraoperative risk factors were the duration of the operation, blood loss during the operation and anaesthesia used. Postoperative risk factors consisted of postoperative biomarkers and postoperative pain. Patient or Public Contribution: The result from this review may assist researchers and healthcare providers in assessing the underlying causes and risk factors of postoperative cognitive dysfunction, and in formulating suitable preventative and therapeutic strategies for older adults with non-neurosurgery during the short-term postoperative period.