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Author: Aasis Unnanuntana

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    A comprehensive approach to fragility fractures
    (2011-09-01) Brian J. Rebolledo; Aasis Unnanuntana; Joseph M. Lane; Weill Cornell Medical College; Hospital for Special Surgery - New York; Mahidol University
    To address the cause of fragility fractures, an understanding of the determinants of bone strength is needed. Identifying patients at increased fracture risk should take into account bone quantity, quality, and turnover. Postmenopausal osteoporosis... remains the most common derangement of bone strength; however, decreased bone strength can also result from secondary causes of osteoporosis. In order to properl y manage patients with fragility fractures, assessment should include a focused medical
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    Atypical femoral fractures: Epidemiology, etiology, and patient management
    (2012-09-01) Eve Donnelly; Anas Saleh; Aasis Unnanuntana; Joseph M. Lane; Cornell University; Hospital for Special Surgery - New York; Mahidol University
    Purpose of review To review the definition, epidemiology, and putative pathophysiology of atypical femoral fractures and propose strategies for the management of patients with atypical fractures as well as patients on long-term bisphosphonates... without atypical fractures. Recent findings Recent epidemiologic evidence shows that the absolute incidence of atypical femoral fractures is small compared with the incidence of typical hip fractures. However, long-term bisphosphonate use may
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    A fracture does not adversely affect bone mineral density responses after teriparatide treatment
    (2012-03-01) Aasis Unnanuntana; Quang V. Ton; John P. Kleimeyer; Joseph T. Nguyen; Joseph M. Lane; Hospital for Special Surgery - New York; Mahidol University; Department of Internal Medicine; Weill Cornell Medical College
    Background Fracture leads to local and systemic catabolic physiologic changes. As teriparatide is an agent used to treat osteoporosis in patients with fragility fractures, it is unclear whether teriparatide treatment alters bone mineral density (BMD...) and bone markers when given to patients with fractures. Questions/purposes We asked whether BMD and bone marker responses would be blunted in patients with fractures placed on teriparatide after fracture compared with patients without fractures
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    Atypical femoral fractures: What do we know about them? AAOS exhibit selection
    (2013-01-16) Aasis Unnanuntana; Anas Saleh; Kofi A. Mensah; John P. Kleimeyer; Joseph M. Lane; Mahidol University; Hospital for Special Surgery - New York; Weill Cornell Medical College
    The causal relationship between prolonged bisphosphonate use and the occurrence of atypical femoral fractures has not yet been established. If a patient sustains an atypical femoral fracture, bisphosphonates must be stopped and an anabolic agent... should be employed. These patients should also have daily calcium and vitamin-D supplementation. As fractures treated by intramedullary nailing heal by endochondral repair, such nailing is a preferred method of fixation for atypical femoral fractures
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    Outcomes of cerclage wiring to manage intra-operative femoral fracture occurring during cementless hemiarthroplasty in older patients with femoral neck fractures
    (2019-11-01) Aasis Unnanuntana; Nakarin Saiyudthong; Faculty of Medicine, Siriraj Hospital, Mahidol University
    © 2019, SICOT aisbl. Background: Cementless hemiarthroplasty is a widely used treatment for femoral neck fractures. Intra-operative femoral fracture occasionally occurs during the procedure, and the use of cerclage wire has been proposed... to stabilize both the prosthesis and the bone. This study aimed to investigate the outcomes of cerclage wiring to manage intra-operative fractures occurring during cementless hemiarthroplasty in older patients with a femoral neck fracture. Methods: Medical
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    The prevalence of hypovitaminosis D in patient with fragility hip fracture at a single institution in Thailand
    (2016-11-01) Suchat Phusunti; Worasit Suthutvoravut; Aasis Unnanuntana; Pojchong Chotiyarnwong; Mahidol University
    © 2016, Medical Association of Thailand. All rights reserved. Background: The proportion of people aged 65 years or older continues to increase in Thailand. Consistent with that trend, the number of fragility fracture patients is increasing.... Hypovitaminosis D is one of the important factors associated with fragility fracture. Objective: To evaluate serum 25-hydroxyvitamin D (25(OH)D) level and prevalence of hypovitaminosis D in patients with fragility hip fracture in Thailand. Material and Method
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    Stress fracture of the femoral shaft in Paget’s disease of bone: A case report
    (2021-05-01) Sarthak Nepal; Atthakorn Jarusriwanna; Aasis Unnanuntana; Siriraj Hospital; Naresuan University
    Paget’s disease of bone (PDB) is a progressive bone disorder characterized by increased osteoclast-mediated bone resorption and abnormal bone formation. Incomplete atypical femoral fracture, appearing radiographically as a stress fracture... at the lateral aspect of the femur, is an uncommon low-trauma fracture frequently seen in association with long-term bisphosphonate therapy. We describe the case of a 61-year-old female patient with PDB who developed a stress fracture at the lateral femoral
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    Prevalence of atypical femoral fractures in Thai patients at a single institution
    (2014-01-01) Sittichai Luangkittikong; Aasis Unnanuntana; Mahidol University
    Objective: Evaluate the prevalence of atypical femoral fracture (AFF) in Thai patients at a single institution based on the 2010 and 2013 American Society of Bone and Mineral Research (ASBMR) criteria and the sensitivity and specificity of each... radiographic feature of AFF to identify bisphosphonate treatment. Material and Method: The authors retrospectively reviewed plain radiographs of 856 patients who were diagnosed with subtrochanteric or femoral shaft fractures between 2002 and 2013. Only those
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    Osteitis Fibrosa Cystica and pathological fractures—the classic but neglected skeletal manifestation of primary hyperparathyroidism: a case report
    (2021-12-01) Ekasame Vanitcharoenkul; Nontouch Singsampun; Aasis Unnanuntana; Sirinart Sirinvaravong; Siriraj Hospital
    of PHPT. Case presentation: A 37-year-old woman was referred to our institution for fixation of multiple fractures of upper and lower extremities that had been reoccurring in the past 5 years. Her medical history showed right-shoulder, left-elbow..., and right-femur fractures after a fall 5 years previously. One month ago, she sustained fractures of the right distal humerus, left tibia, and left femur without history of trauma. Upon arrival to our hospital, a thorough review of her plain radiographs
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    Trunnion Fracture of the Anatomic Medullary Locking A Plus Femoral Component
    (2011-04-01) Aasis Unnanuntana; Dan X. Chen; Amnuay Unnanuntana; Timothy M. Wright; Mahidol University; Hospital for Special Surgery - New York
    Fracture of the neck of the femoral component after total hip arthroplasty is an infrequent complication. We present a report of 2 cases of trunnion fractures of fully porous-coated femoral stems (AML A Plus, DePuy International, Leeds, England... contributing to the initiation of the failure was noted. Although this is the first report of trunnion fractures in this particular implant design, a close monitoring of prostheses with this specific trunnion should be considered. In addition, further analysis