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Publication Metadata only Combined iron and zinc supplementation in infants improved iron and zinc status, but interactions reduced efficacy in a multicountry trial in Southeast Asia(2007-02-01) Frank T. Wieringa; Jacques Berger; Marjoleine A. Dijkhuizen; Adi Hidayat; Nguyen X. Ninh; Budi Utomo; Emorn Wasantwisut; Pattanee Winichagoon; Radboud University Nijmegen Medical Centre; IRD Centre de Montpellier; Universitas Trisakti; National Institute of Nutrition Vietnam; Universitas Indonesia; Mahidol UniversityDeficiencies of iron and zinc are prevalent worldwide. Interactions between these micronutrients therefore have important consequences, also for supplementation. To investigate effects on hemoglobin and zinc concentrations and interactions of iron... and zinc supplementation in infants, data from 4 parallel, randomized, placebo-controlled, double-blind trials in Indonesia, Thailand, and Vietnam were pooled. Infants (n = 2468), aged 4-6 mo, were supplemented daily with iron (10 mg) and/or zinc (10 mgPublication Metadata only Zinc supplementation improved length growth only in anemic infants in a multi-country trial of iron and zinc supplementation in South-East Asia(2008-10-01) Marjoleine A. Dijkhuizen; Pattanee Winichagoon; Frank T. Wieringa; Emorn Wasantwisut; Budi Utomo; Nguyen X. Ninh; Adi Hidayat; Jacques Berger; London School of Hygiene & Tropical Medicine; Mahidol University; IRD Centre de Montpellier; Universitas Indonesia; National Institute of Nutrition Vietnam; Universitas TrisaktiData from 4 randomized, placebo-controlled, double-blind trials in Indonesia, Thailand, and Vietnam, the South-East Asian Multicountry Trial on Iron and Zinc supplementation in Infants (SEAMTIZI), were pooled to investigate the effects of iron... and zinc supplementation infant growth. Infants (n = 2451) aged 4-6 mo old were supplemented with iron (10 mg/d) and/ or zinc (10 mg/d) for 6 mo. Overall, neither iron nor zinc supplementation prevented the progressive growth faltering during infancy, whichPublication Metadata only Community Mobilization and Social Marketing to Promote Weekly Iron-Folic Acid Supplementation in Women of Reproductive Age in Vietnam: Impact on Anemia and Iron Status(2005-12-01) Jacques Berger; Hoang Thi Kim Thanh; Tommaso Cavalli-Sforza; Suttilak Smitasiri; Nguyen Cong Khan; Silvano Milani; Pham Thuy Hoa; Nguyen Dinh Quang; Fernando Viteri; IRD Centre de Montpellier; National Nutrition Institute; Organisation Mondiale de la Sante; Mahidol University; UNICEF; Institute of Medical Statistics and Biometry; Children's Hospital Oakland Research InstituteThe community mobilization and social marketing program promoting a preventive approach of weekly iron-folic acid supplementation in women of reproductive age improved iron status of non-pregnant women in Vietnam. Three to six months of weekly pre...-pregnancy supplementation and regular weekly intake of supplements during pregnancy allowed women to achieve good iron and hemoglobin status during the two first trimesters of pregnancy. In the third trimester, iron deficiency and anemia were notably presentPublication Metadata only Community Mobilization and Social Marketing to Promote Weekly Iron-Folic Acid Supplementation: A New Approach Toward Controlling Anemia Among Women of Reproductive Age in Vietnam(2005-12-01) Nguyen Cong Khan; Hoang Thi Kim Thanh; Jacques Berger; Pham Thuy Hoa; Nguyen Dinh Quang; Suttilak Smitasiri; Tommaso Cavalli-Sforza; National Institute of Nutrition Vietnam; IRD Centre de Montpellier; UNICEF; Mahidol University; The World Health Organization Regional Office for the Western Pacific philippinesCommunity-based social marketing and mobilization increased knowledge and participation in preventive weekly iron-folic acid supplementation among women of reproductive age in Vietnam. Rates of buying and taking the weekly supplement containing 60... mg elemental iron and 3.5 mg folic acid among non-pregnant women of reproductive age was between 55% and 92%. Free distribution to pregnant women of the weekly supplement containing 120 mg iron and 3.5 mg folic acid covered almost all pregnant womenPublication Metadata only Asian workshop on iron fortification of foods(2005-04-27) Rodolfo F. Florentino; Barbara Underwood; Richard Hurrell; Junshi Chen; Huo Junsheng; Naihu Ju; Nguyen Cong Khan; Phan Van Thuy; Takashi Togami; Budianto Wijaya; Corazon V C Barba; Pattanee Winichagoon; Visith Chavasit; Arun Kelkar; Jacques Berger; Chen Chunming; Sonya Rabeneck; Nutrition Center of the Philippines; National Academy of Sciences; Ecoles polytechniques federales; Institute of Nutrition and Food Safety; Unilever; National Institute of Nutrition; ILSI; Food and Nutrition Research Institute Manila; Mahidol University; Hexagon Chemoils Pvt. Ltd; IRD Institut de Recherche pour le DeveloppementPublication Metadata only Growth, stunting, and micronutrient supplementation: Perspectives fromthe south-east Asia multi-country trial of iron and zinc supplementation in infants (SEAMTIZI)(2012-01-01) Frank T. Wieringa; Marjoleine A. Dijkhuizen; Pattanee Winichagoon; Emorn Wasantwisut; Budi Utomo; Nguyen X. Ninh; Adi Hidayat; Jacques Berger; Montpellier SupAgro; Kobenhavns Universitet; Mahidol University; Universitas Indonesia; National Institute of Nutrition Vietnam; Universitas Trisakti; IRD Centre de Montpellierwhether inadequate intakes of iron and/or zinc contribute to growth faltering in infancy in South-East Asia, a multi-country trial was conducted between 1997 and 2000: the SEAMTIZI trial with study sites in Vietnam, Thailand, and Indonesia (two sites...). In the SEAMTIZI trial, infants (mean age 5 months) received 10 mg of iron, 10 mg of zinc, 10 mg of both iron and zinc, or placebo daily for 6 months. The SEAMTIZI trial showed that blanket supplementation with iron or zinc could not prevent the progressivePublication Metadata only Sex differences in prevalence of anaemia and iron deficiency in infancy in a large multi-country trial in South-East Asia(2007-11-01) Frank T. Wieringa; Jacques Berger; Marjoleine A. Dijkhuizen; Adi Hidayat; Nguyen X. Ninh; Budi Utomo; Emorn Wasantwisut; Pattanee Winichagoon; Radboud University Nijmegen Medical Centre; IRD Centre de Montpellier; National Institute of Nutrition Vietnam; Universitas Trisakti; Universitas Indonesia; Mahidol University; Nutrition Research and Development Centre, BogorTo evaluate effects of Fe supplementation and sex on the prevalence of anaemia and Fe status in infants in South-East Asia, biochemical data from four parallel, randomized, double-blind trials with Fe and/or Zn supplementation in infants (n 2452) in Indonesia, Thailand and Vietnam was pooled. At recruitment (5 months of age), Hb concentrations were slightly but significantly lower in boy infants compared with girl infants (108.7 g/l v. 111.4 g/l, P = 0.04). At 11 months of age, boy infants not receiving Fe had significantly lower Hb (106.2g/l v. 111.0 g/l, P<0.001) and lower serum ferritin concentrations (14.3 μg/l v. 21.1g/l, P<0.001) than girl infants not receiving Fe. Consequently, boy infants had a relative risk of 1.6 (95 % CI 1.3, 2.1) to be anaemic, and of 3.3 (95 % CI 2.1, 5.0) for having Fe deficiency anaemia compared with girl infants. Fe supplementation significantly increased Hb concentrations in both boys and girls. There was no sex difference in Fe status in infants receiving Fe for 6 months. This study shows that the markedly higher risk for anaemia and Fe deficiency indicates higher Fe requirements in boy than in girl infants. In South-East Asia, standard infant feeding practices do not provide sufficient Fe to meet requirements of infants, especially boys. Current daily recommended intake for Fe in infancy is the same for boy and girl infants however. Our findings suggest that in especially the second half of infancy, Fe requirements for boy infants are approximately 0.9 mg/d higher than for girl infants. © 2007 The Authors.Publication Metadata only Realistic Food-Based Approaches Alone May Not Ensure Dietary Adequacy for Women and Young Children in South-East Asia(2019-01-15) Elaine L. Ferguson; Louise Watson; Jacques Berger; Mary Chea; Uraiporn Chittchang; Umi Fahmida; Kuong Khov; Sengchanh Kounnavong; Bach Mai Le; Nipa Rojroongwasinkul; Otte Santika; Seyha Sok; Daream Sok; Tran Thanh Do; Lua Tran Thi; Manithong Vonglokham; Frank Wieringa; Emorn Wasantwisut; Pattanee Winichagoon; Ministry of Health Cambodia; National Institute of Nutrition Vietnam; Universitas Indonesia; London School of Hygiene & Tropical Medicine; IRD Centre de Montpellier; Mahidol University; Ministry of Agriculture; National Institute of Public Healthof inadequate intakes for five to ten micronutrients, depending on the country and target population. Of the 11 micronutrients modelled, requirements for iron, calcium and folate were most difficult to meet (≥ 10 of the 24 target populations), using FBRs alone