60 results
Search Results
Now showing 1 - 10 of 60
Item Metadata only Prevalence and proportion estimate of asymptomatic Plasmodium infection in Asia: a systematic review and meta-analysis(2023-12-01) Kotepui M.; Kotepui K.U.; Masangkay F.R.; Mahittikorn A.; Wilairatana P.; Mahidol UniversityAsymptomatic Plasmodium infection raises a problem for the persistent transmission of malaria in low-endemic areas such as Asia. This systematic review was undertaken to estimate the prevalence and proportion of asymptomatic Plasmodium infection... in Asia. The systematic review was registered at PROSPERO (ID: CRD42022373664). The research followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. A comprehensive search of five databases, Ovid, Scopus, MEDLINE, PubItem Metadata only Low Interleukin-12 Levels concerning Severe Malaria: A Systematic Review and Meta-Analysis(2022-08-01) Wilairatana P.; Kwankaew P.; Kotepui K.U.; Kotepui M.; Mahidol University-12 levels between patients with severe and uncomplicated malaria through a meta-analysis. A systematic review was conducted following the Cochrane Handbook for Systematic Reviews of Interventions and was reported according to the Preferred Reporting... Items for Systematic reviews and Meta-Analyses statement. Systematic literature searches were performed between 20 February and 2 March, 2022 in PubMed, Scopus, and Embase to identify studies reporting IL-12 levels in patients with severeItem Metadata only Alteration of ceruloplasmin in patients with malaria: a systematic review and meta-analysis of observational studies(2024-12-01) Kotepui K.U.; Mahittikorn A.; Wilairatana P.; Masangkay F.R.; Kotepui M.; Kotepui K.U.; Mahidol UniversityBackground: The evidences of oxidative stress-related Plasmodium infection may alter the ceruloplasmin levels were inconsistent. This systematic review and meta-analysis aimed to collate and synthesize literatures on malaria and ceruloplasmin... concentrations. Methods: The systematic review has been registered with PROSPERO (CRD42023454859). Six electronic databases were systematically searched for investigated ceruloplasmin levels in malaria: ProQuest, EMBASE, MEDLINE, Ovid, PubMed, and Scopus, fromItem Metadata only Interleukin-5 levels in relation to malaria severity: a systematic review(2023-08-03) Kotepui M.; Duangchan T.; Mahittikorn A.; Mekhora C.; Anabire N.G.; Kotepui K.U.; Mahidol UniversityBACKGROUND: The role of cytokines such as interleukin-5 (IL-5) in the pathogenesis of malaria remains unclear. This systematic review sought to synthesize variations in IL-5 levels between severe and uncomplicated malaria, as well as between malaria... and controls not afflicted with the disease. METHODS: This systematic review was registered at the International Prospective Register of Systematic Reviews (PROSPERO; CRD42022368773). Searches for studies that reported IL-5 levels in patients with malaria (anyItem Metadata only Association between RANTES/CCL5 levels with Plasmodium infections and malaria severity: a systematic review(2024-11-09) Kwankaew P.; Mahittikorn A.; Mala W.; Kotepui K.U.; Anabire N.G.; Wilairatana P.; Kotepui M.; Kwankaew P.; Mahidol UniversityBACKGROUND: Malaria continues to be a significant global health concern, and developing effective therapeutic strategies requires an understanding of the immune response to the disease. This systematic review synthesized the current body of research... on the role of regulated on activation, normal T cell expressed and secreted (RANTES)-in the pathogenesis and disease severity of malaria. METHODS: A systematic review protocol was registered with PROSPERO under the registration number CRD42024535822Item Metadata only Association between Plasmodium Infection and Nitric Oxide Levels: A Systematic Review and Meta-Analysis(2023-10-01) Kotepui K.U.; Mahittikorn A.; Wilairatana P.; Masangkay F.R.; Kotepui M.; Mahidol UniversityNitric oxide (NO) has been implicated in the pathology of malaria. This systematic review and meta-analysis describe the association between NO levels and malaria. Embase, Ovid, PubMed, Scopus, and Google Scholar were searched to identify studies... evaluating NO levels in malaria patients and uninfected controls. Meta-regression and subgroup analyses were conducted to discern differences in NO levels between the groups. Of the 4517 records identified, 21 studies were included in the systematic reviewItem Metadata only A systematic review of circulating IP-10/CXCL10 in patients with Plasmodium infections in relation to disease severity(2024-12-01) Kotepui M.; Mahittikorn A.; Masangkay F.R.; Kotepui K.U.; Kotepui M.; Mahidol University. This systematic review aimed to collate and critically appraise the current evidence on IP-10 levels in malaria patients. It provided insights into its role in malaria pathogenesis and potential as a biomarker for Plasmodium infections and disease severity.... The protocol for this systematic review was registered in PROSPERO (number CRD42024556087). A comprehensive literature search was conducted across multiple databases, including Embase, PubMed, Scopus, Ovid, ProQuest, and MEDLINE, to identify relevant studiesItem Metadata only Prevalence of Cryptosporidium Infections in Thailand and Its Association with HIV and Diarrhea: A Systematic Review and Meta-Analysis(2025-08-26) Kotepui M.; Mahittikorn A.; Jongthawin J.; Rattanawan C.; Masangkay F.R.; Kotepui M.; Mahidol UniversityCryptosporidium is a protozoan parasite and a major cause of diarrhea, especially in children and immunocompromised individuals. Despite evidence of its presence in Thailand, comprehensive national data remain limited. This systematic review... and meta-analysis aimed to estimate the prevalence of Cryptosporidium infection in Thailand and assess its association with diarrhea, especially among vulnerable populations, to support targeted public health strategies. This systematic review followedItem Metadata only Association between interleukin-2 cytokine levels and Plasmodium infections: a systematic review and meta-analysis(2025-12-01) Kwankaew P.; Kotepui K.U.; Anabire N.G.; Wilairatana P.; Kotepui M.; Kwankaew P.; Mahidol Universitystudied in malaria pathogenesis, the role of IL-2 remains poorly understood and inconsistently reported across studies. This systematic review and meta-analysis aimed to synthesize available evidence on IL-2 levels in malaria patients and assess... their association with disease severity. Methods: A systematic search was conducted across five databases (PubMed, MEDLINE, EMBASE, Scopus, and CENTRAL) without date restrictions. Studies were eligible if they reported IL-2 levels in human participants with malariaItem Metadata only Effect of Malaria on Blood Levels of Vitamin E: A Systematic Review and Meta-Analysis(2023-08-01) Kotepui M.; Masangkay F.R.; Mahittikorn A.; Kotepui K.U.; Mahidol UniversityVitamin E has an antioxidant property and is associated with protection against malaria. The current study used systematic review and meta-analysis approaches examining the variance in blood levels of vitamin E in malaria patients as compared... with uninfected individuals. The protocol for the systematic review was registered with PROSPERO (CRD4202341481). Searches for pertinent studies were carried out on Embase, MEDLINE, Ovid, PubMed, Scopus, ProQuest, and Google Scholar. The combined effect estimate