20 results
Search Results
Now showing 1 - 10 of 20
Publication Metadata only Thailand Diabetes Registry Project: Prevalence of diabetic retinopathy and associated factors in type 1 diabetes mellitus(2006-08-01) Thanya Chetthakul; Supawadee Likitmaskul; Nattachet Plengvidhya; Sompongse Suwanwalaikorn; Natapong Kosachunhanun; Chaicharn Deerochanawong; Sirinate Krittiyawong; Rattana Leelawatana; Yupin Benjasuratwong; Pongamorn Bunnag; Thongchai Prathipanawatr; Chardpraorn Ngarmukos; Sirima Mongkolsomlit; Petch Rawdaree; Maharat Nakhon Ratchasima Hospital; Mahidol University; Chulalongkorn University; Chiang Mai University; Theptarin General Hospital; Prince of Songkla University; Phramongkutklao Hospital; Khon Kaen University; Vajira Hospital; Division of Endocrinologyof patients with type 1 diabetes was 347. The prevalence of DR in type 1 diabetes was 21.6% (75). This consisted of Non-Proliferative DR (NPDR) 10.9% (38) and Proliferative DR (PDR) 10.7%. Patients with DR were significantly older, predominantly female, longer... with creatinine less than 2 mg/dl. From the presented model, age, gender, systolic BP > 140 mmHg, diastolic BP > 90 mmHg, serum TG and smoking status were not factors associated with DR. Conclusion: Diabetic retinopathy affects about one fifth of type 1 diabeticPublication Metadata only Thailand Diabetes Registry Project: Prevalence of diabetic retinopathy and associated factors in type 2 diabetes mellitus(2006-08-01) Thanya Chetthakul; Chaicharn Deerochanawong; Sompongse Suwanwalaikorn; Natapong Kosachunhanun; Chardpraorn Ngarmukos; Petch Rawdaree; Sirinate Krittiyawong; Rattana Leelawatana; Pongamorn Bunnag; Nattachet Plengvidhya; Thongchai Pratipanawatr; Yupin Benjasuratwong; Sirima Mongkolsomlit; Maharat Nakhon Ratchasima Hospital; Rajavithi Hospital; Chulalongkorn University; Chiang Mai University; Mahidol University; Vajira Hospital; Theptarin General Hospital; Prince of Songkla University; Khon Kaen University; Phramongkutklao Hospital; Division of Endocrinologyophthalmoscopy after full dilatation of pupils. 6,707 cases were type 2 diabetic patients. The prevalence of DR was 31.4% (N = 2105) which consisted of Non-Proliferative DR (NPDR) 22% (N = 1475), Proliferative DR (PDR) 9.4% (N = 630). Patients with DR were... (3.3 [2.29-4.70]) when compared with no nephropathy. Conclusion: Diabetic retinopathy was present in about one third of type 2 diabetic patients in Thailand. The authors found the factors associated with DR were duration of diabetes, latest HbA1cPublication Metadata only Mutations of maturity-onset diabetes of the young (MODY) genes in Thais with early-onset type 2 diabetes mellitus: ORIGINAL ARTICLE(2009-06-01) Nattachet Plengvidhya; Watip Boonyasrisawat; Nalinee Chongjaroen; Prapaporn Jungtrakoon; Sutin Sriussadaporn; Sathit Vannaseang; Napatawn Banchuin; Pa Thai Yenchitsomanus; Division of Endocrinology and Metabolism; Department of Immunology; Mahidol UniversityObjective Six known genes responsible for maturity-onset diabetes of the young (MODY) were analysed to evaluate the prevalence of their mutations in Thai patients with MODY and early-onset type 2 diabetes. Patients and methods Fifty-one unrelated... and early-onset type 2 diabetes in Thais. Therefore, unidentified genes await discovery in a majority of Thai patients with MODY and early-onset type 2 diabetes. © 2009 Blackwell Publishing Ltd.Publication Metadata only Thailand Diabetes Registry Project: Prevalence of vascular complications in long-standing type 2 diabetes(2006-08-01) Rattana Leelawattana; Thongchai Pratipanawatr; Pongamorn Bunnag; Natapong Kosachunhanun; Sompongse Suwanwalaikorn; Sirinate Krittiyawong; Thanya Chetthakul; Nattachet Plengvidhya; Yupin Benjasuratwong; Chaicharn Deerochanawong; Sirima Mongkolsomlit; Chardpraorn Ngarmukos; Petch Rawdaree; Prince of Songkla University; Khon Kaen University; Mahidol University; Chiang Mai University; Chulalongkorn University; Theptarin General Hospital; Maharat Nakhon Ratchasima Hospital; Phramongkutklao Hospital; Rajavithi Hospital; Vajira HospitalObjective: To explore the nature of diabetic complications in type 2 diabetic patients who had had diabetes for longer than 15 years (long-DM), compared to those with duration of less than 15 years (short-DM). Material and Method: Patients studied... were adult type 2 diabetic patients registered to the Diabetes Registry Project, a nationwide cross-sectional study of diabetes mellitus in Thailand. Information collected included demographic data, age at diagnosis of diabetes, blood pressure, bodyPublication Metadata only Thailand Diabetes Registry Project: Glycemic control in Thai type 2 diabetes and its relation to hypoglycemic agent usage(2006-08-01) Natapong Kosachunhanun; Yupin Benjasuratwong; Sirima Mongkolsomlit; Petch Rawdaree; Nattachet Plengvidhya; Rattana Leelawatana; Pongamorn Bunnag; Thongchai Pratipanawatr; Sirinate Krittiyawong; Sompongse Suwanwalaikorn; Chaicharn Deerochanawong; Thanya Chetthakul; Chardpraorn Ngarmukos; Chulaluk Komoltri; Chiang Mai University; Phramongkutklao Hospital; Vajira Hospital; Mahidol University; Prince of Songkla University; Khon Kaen University; Theptarin General Hospital; Chulalongkorn University; Rajavithi Hospital; Maharat Nakhon Ratchasima Hospitalof treatment was also analyzed. Material and Method: A cross-sectional, hospital-based diabetes registry of 8,913 type 2 diabetic patients in 11 tertiary care hospitals and medical schools was carried out from April to December 2003. Demographic data, usage...Objective: To determine the pattern of hyperglycemic agent usage in Thai type 2 diabetics (T2 DM) who attended the diabetes clinic in university and tertiary-care hospitals. The achievement of target glycemic control by various modalitiesPublication Metadata only Withdrawal of sulfonylureas from patients with type 2 diabetes receiving long-term sulfonylurea and insulin combination therapy results in deterioration of glycemic control: A randomized controlled trial(2015-03-02) Weerachai Srivanichakorn; Apiradee Sriwijitkamol; Aroon Kongchoo; Sutin Sriussadaporn; Nattachet Plengvidhya; R. Aweewan Lertwattanarak; Sathit Vannasaeng; Nuntakorn Thongtang; Mahidol University© 2015 Srivanichakorn et al. Background: The benefit of sulfonylureas (SUs) to patients with type 2 diabetes mellitus receiving long-term insulin treatment is unclear. This study evaluated glycemic control and beta-cell function after SU withdrawal... in these patients. Methods: In this 8-week randomized controlled study, patients with type 2 diabetes who had been treated with insulin for at least 3 years plus moderate to high doses of SUs were randomly assigned to withdrawal (n=16) or continuation (n=16) of SUsPublication Metadata only Detection of CAPN10 copy number variation in Thai patients with type 2 diabetes by denaturing high performance liquid chromatography and real-time quantitative polymerase chain reaction(2015-01-01) Nattachet Plengvidhya; Kanjana Chanprasert; Watip Tangjittipokin; Wanna Thongnoppakhun; Pa thai Yenchitsomanus; Mahidol University© 2015 Asian Association for the Study of Diabetes and Wiley Publishing Asia Pty Ltd. Aims/Introduction: A combination of multiple genetic and environmental factors contribute to the pathogenesis of type 2 diabetes. Copy number variations (CNVs... of genotype calling based on the status of identified CNVs showed that the CAPN10 SNP44 genotype is in good agreement with HWE (P > 0.05). However, no association between CNV genotypes and risk of type 2 diabetes was observed. Conclusions: Identified CNVsPublication Metadata only Thailand Diabetes Registry Project: Prevalence of hypertension, treatment and control of blood pressure in hypertensive adults with type 2 diabetes(2006-08-01) Pongamorn Bunnag; Nattachet Plengvidhya; Chaicharn Deerochanawong; Sompongse Suwanwalaikorn; Natapong Kosachunhanun; Yupin Benjasuratwong; Sirinate Krittiyawong; Rattana Leelawatana; Thongchai Pratipanawatr; Chardpraorn Ngarmukos; Thanya Chetthakul; Gobchai Puavilai; Sirima Mongkolsomlit; Petch Rawdaree; Vajira Hospital; Rajavithi Hospital; Chiang Mai University; Prince of Songkla University; Chulalongkorn University; Theptarin General Hospital; Khon Kaen University; Maharat Nakhon Ratchasima Hospital; Phramongkutklao Hospital; Mahidol University; Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityObjective: To determine the prevalence of hypertension, patterns of antihypertensive treatment and level of blood pressure control in adult Thai type 2 diabetic patients who attended diabetes clinics in university and tertiary-care hospitals... samples were collected and analyzed for prevalence, associated factors, patterns of antihypertensive therapy and level of blood pressure control. Results: The prevalence of hypertension in adult Thai type 2 diabetic patients was 78.4 (6Publication Metadata only Thailand Diabetes Registry Project: Current status of dyslipidemia in Thai diabetic patients(2006-08-01) Thongchai Pratipanawatr; Petch Rawdaree; Thanya Chetthakul; Pongamorn Bunnag; Chardpraorn Ngarmukos; Yupin Benjasuratwong; Rattana Leelawatana; Natapong Kosachunhanun; Nattachet Plengvidhya; Chaicharn Deerochanawong; Sompongse Suwanwalaikorn; Sirinate Krittiyawong; Sirima Mongkolsomlit; Chulaluk Komoltri; Khon Kaen University; Vajira Hospital; Maharat Nakhon Ratchasrima Hospital; Mahidol University; Phramongkutklao Hospital; Prince of Songkla University; Chiang Mai University; Rajavithi Hospital; Chulalongkorn University; Theptarin General Hospital. Results: Of the 9,419 diabetic patients registered 8,769 had complete demographic and plasma lipid data. Mean age was 59.5 □ 13.3 years. The percentage of male patients was 33.9%. In the present study, there were 8464 type 2 diabetes and 383 type 1...Objective: To determine the prevalence of dyslipidemia in adult Thai type 2 diabetes who attended diabetes clinics in university and tertiary-care hospitals. Material and Method: A cross-sectional, multi-center, hospital-based diabetes registryPublication Open Access Novel adiponectin variants identified in type 2 diabetic patients reveal multimerization and secretion defects(2011) Prapaporn Jungtrakoon; Nattachet Plengvidhya; Watip Tangjittipokin; Sarin Chimnaronk; Wanisa Salaemae; Nalinee Chongjaroen; Kanjana Chanprasert; Jatuporn Sujjitjoon; Chatchawan Srisawat; Pa-thai Yenchitsomanus; Mahidol University. Faculty of Medical Technology. Department of Clinical Microscopy; Mahidol University. Faculty of Medicine Siriraj Hospital. Department of Medicine; Mahidol University. Institute of Molecular Biosciences.ADIPOQ, encoding adiponectin, is a candidate gene for type 2 diabetes (T2D) identified by genome-wide linkage analyses with supporting evidence showing the protein function in sensitizing insulin actions. In an endeavor to characterize candidate... genes causing T2D in Thai patients, we identified 10 novel ADIPOQ variations, several of which were non-synonymous variations observed only in the patients. To examine the impact of these non-synonymous variations on adiponectin structure and biochemical