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Now showing 1 - 8 of 8
  • Publication
    Siver nanoparticles toxicity in brine shrimp and its histopathological analysis
    (2018-12-01) Supicha Kachenton; Varanut Whangpurikul; Niwat Kangwanrangsan; Tawewan Tansatit; Wannee Jiraungkoorskul; Mahidol University
    of industrial household products. Increasing usage of Ag NPs every year leads to increased risk of nanomaterial contamination in the environment, especially natural water sources with harmful effects in aquatic animals, and to ecosystem disruption... from basement muscle lining, and necrosis area. These findings indicated the effect of Ag NPs and their negative impact on aquatic animals which might lead to further disruption of ecosystem.
  • Publication
    Identification of a PH domain-containing protein which is localized to crystalloid bodies of Plasmodium ookinetes
    (2018-12-13) Rachaneeporn Jenwithisuk; Niwat Kangwanrangsan; Mayumi Tachibana; Amporn Thongkukiatkul; Hitoshi Otsuki; Jetsumon Sattabongkot; Takafumi Tsuboi; Motomi Torii; Tomoko Ishino; Mahidol University; Tottori University; Burapha University; Ehime University
    antibodies against PyCryPH were obtained to characterize the expression and localization of PyCryPH during sexual-stage parasite development. In addition, PyCryPH knockout parasites were generated by targeted gene disruption to examine PyCryPH function...CryPH is localized within crystalloid bodies. Parasites with a disrupted PyCryPH gene developed normally into ookinetes and formed oocysts on the basal lamina of midguts. In addition, the number of sporozoites residing in salivary glands was comparable
  • Publication
    A member of the CPW-WPC protein family is expressed in and localized to the surface of developing ookinetes
    (2013-04-17) Niwat Kangwanrangsan; Mayumi Tachibana; Rachaneeporn Jenwithisuk; Takafumi Tsuboi; Suda Riengrojpitak; Motomi Torii; Tomoko Ishino; Ehime University; Mahidol University
    investigated by the generation of gene-disrupted transgenic parasites. Results: The CPW-WPC protein family, named after the unique WxC repeat domains, is highly conserved among Plasmodium species. It is revealed that CPW-WPC mRNA transcripts are transcribed... disruption of the pycpw-wpc-1 gene caused no obvious defects during ookinete and oocyst formation, suggesting that PyCPW-WPC-1 is not essential for mosquito-stage parasite development. Conclusions: It is demonstrated that PyCPW-WPC-1 can be classified as a
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    PublicationOpen Access
    A member of the CPW-WPC protein family is expressed in and localized to the surface of developing ookinetes.
    (2013-04-15) Niwat Kangwanrangsan; Tachibana, Mayum; Rachaneeporn Jenwithisuk; รัชนีพร เจนวิถีสุข; Tsuboi, Takafumi; Suda Riengrojpitak; Torii, Motom; Ishino, Tomoko; Ishino, Tomoko; Mahidol University. Faculty of Tropical Medicine. Mahidol Vivax Research Unit; Mahidol University. Faculty of Science. Department of Pathobiology
    investigated by the generation of gene-disrupted transgenic parasites. RESULTS: The CPW-WPC protein family, named after the unique WxC repeat domains, is highly conserved among Plasmodium species. It is revealed that CPW-WPC mRNA transcripts are transcribed... disruption of the pycpw-wpc-1 gene caused no obvious defects during ookinete and oocyst formation, suggesting that PyCPW-WPC-1 is not essential for mosquito-stage parasite development. CONCLUSIONS: It is demonstrated that PyCPW-WPC-1 can be classified as a
  • Publication
    Eurytrema pancreaticum: The in vitro effect of praziquantel and triclabendazole on the adult fluke
    (2005-11-01) Wannee Jiraungkoorskul; Somphong Sahaphong; Tawewan Tansatit; Niwat Kangwanrangsan; Siriporn Pipatshukiat; Mahidol University
    and disintegration of the tegument disrupting the worms' outer surface including detachment of spines in the PZQ treatment. The cells in testes were slightly increased in size and followed by degeneration leaving several hollow spaces. The uterus and vitelline glands
  • Publication
    Schistosoma mekongi: The in vitro effect of praziquantel and artesunate on the adult fluke
    (2006-05-01) Wannee Jiraungkoorskul; Somphong Sahaphong; Prasert Sobhon; Suda Riengrojpitak; Niwat Kangwanrangsan; Mahidol University
    as little as 3 h incubation with PZQ and ATS. Some of the worms were immobile 12 h after exposure, and died within 24 h. The tegument of S. mekongi showed severe swelling, vacuolization and disruption, fusion of the tegumental ridges, collapse and peeling
  • Publication
    Cytotoxicity and histopathological analysis of titanium nanoparticles via Artemia salina
    (2019-05-01) Supicha Kachenton; Wannee Jiraungkoorskul; Niwat Kangwanrangsan; Tawewan Tansatit; Mahidol University
    on aquatic microcrustaceans and their negative impact on the ecosystem. Furthermore, this information will aid the elucidation of TiNP toxicity effect and the risk of ecosystem disruptions.
  • Publication
    Schistosoma Mekongi: the in vitro effect of praziquantel and artesunate on the adult fluke.
    (2006) Wannee Jiraungkoorskul; Somphong Sahaphong; Prasert Sobhon; suda Riengrojpitak; Niwat Kangwanrangsan; วรรณีย์ จิรอังกูรสกุล; สมพงศ์ สหพงศ์; ประเสริฐ โศภณ; สุดา เรียงโรจน์พิทักษ์; นิวัฒน์ กังวานรังสรรค์; Mahidol University. International College. Science Division.
    as little as 3 h incubation with PZQ and ATS. Some of the worms were immobile 12 h after exposure, and died within 24 h. The tegument of S. mekongi showed severe swelling, vacuolization and disruption, fusion of the tegumental ridges, collapse and peeling