4 results
Search Results
Now showing 1 - 4 of 4
Publication Metadata only Regulatory role of ovarian sex hormones in calcium uptake activity of cardiac sarcoplasmic reticulum(2006-09-13) Tepmanas Bupha-Intr; Jonggonnee Wattanapermpool; Mahidol Universityintracellular Ca2+mobilization, the sarcoplasmic reticulum (SR) Ca2+uptake and SR Ca2+-ATPase (SERCA) activity were determined in 10-wk ovariectomized rat hearts. With the use of left ventricular homogenate preparations, a significant suppression of maximum SRPublication Metadata only Acute inhibitory effect of alpha-mangostin on sarcoplasmic reticulum calcium-ATPase and myocardial relaxation(2017-10-01) Sukanya Phungphong; Anusak Kijtawornrat; Pieter P. de Tombe; Jonggonnee Wattanapermpool; Tepmanas Bupha-Intr; Sunit Suksamrarn; Mahidol University; Chulalongkorn University; Loyola University Stritch School of Medicine; Srinakharinwirot Universitysarcoplasmic reticulum (SR) membrane preparation, α-mangostin inhibited SR Ca2+-ATPase activity in a dose-dependent manner (IC50of 6.47 ± 0.7 μM). Its suppressive effect was specific to SR Ca2+-ATPase but not to myofibrillar Ca2+-ATPase. Using isolatedPublication Metadata only Testosterone regulates cardiac contractile activation by modulating SERCA but not NCX activity(2013-02-01) Namthip Witayavanitkul; Warunya Woranush; Tepmanas Bupha-Intr; Jonggonnee Wattanapermpool; Mahidol Universitytension was also suppressed in ORX rats without changes in myofilament Ca2+sensitivity and passive stiffness of the heart. Using a sarcoplasmic reticulum-enriched membrane preparation, the maximum thapsigargin-sensitive SERCA activity of the ORX rat was 27... relaxation, Ca2+-handling activities by sarco-(endo)plasmic reticulum Ca2+-ATPase (SERCA) and the Na+/Ca2+exchanger (NCX) were evaluated in the ventricular muscle of 10-wk-old ORX rats with and without testosterone supplementation (2.5 mg/kg testosteronePublication Metadata only Moderate intensity of regular exercise improves cardiac SR Ca2+ uptake activity in ovariectomized rats(2009-10-01) Tepmanas Bupha-Intr; Jitanan Laosiripisan; Jonggonnee Wattanapermpool; Mahidol UniversityThe impact of regular exercise in protecting cardiac deteriorating results of female sex hormone deprivation was evaluated by measuring changes in intracellular Ca2+removal activity of sarcoplasmic reticulum (SR) in ovariectomized rats following 9