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Item Metadata only Biological sequence analysis(Mahidol University. Mahidol University Library and Knowledge Center, 2001) Direk Takmatcha; Damras Wongsawang; Prasit PalittapongarnpimItem Metadata only Nucleotide sequences of a malaria DNA probe and a mosquito larvicidal endotoxin gene as determined by the sanger's dideoxy method(Mahidol University. Mahidol University Library and Knowledge Center, 1986) Chatri Settasatian; Prapon Wilairat; Sakol Panyim; Thanit KusamranItem Metadata only Application of continuous flow technique for sequential extraction and for determination of phosphorus in soil and sediment(Mahidol University. Mahidol University Library and Knowledge Center, 2002) Warawut Tiyapongpattana; Duangjai Nacapricha; Juwadee ShiowatanaItem Open Access Bioengineering of bacteriophage-derived endolysin against Clostridioides difficile(Mahidol University, 2022) Wichuda Phothichaisri; Sittinan Chanarat; Surang Chankhamhaengdecha; Tavan Janvilisrifortherapeutic purposes, the fundamental role of the enzyme is needed. In this study, an identical endolysin was identified from two C. difficile phages, ΦHN16-1 and ΦHN50, designated as CD16/50. The sequence analysis revealed a modular architecture of an N... lytic activity faster than the full-length, suggesting a CBD-independent activity. The study also showed that the CBD formed a homodimer essential for interaction with cell-wall polymer. Interestingly, the hidden Markov model analysis suggestedItem Metadata only Kinetic study of D-galactosamine, 6-azauridine and 5-fluorouridine in chemotherapy of hepatoma(Mahidol University. Mahidol University Library and Knowledge Center, 1987) Yaowapa Maneerat; Tongtavuch Anukarahanonta.6-AzaUrd, 5-FUrd and Urd in ascitic fluid and AS-30D cells were analysed by reversed phase HPLC system and detected with coupled UV spectrophotometre. The concentration determined by peak-height analysis were used for kinetic analysis of drugs... and cells. In addtition, pretreatment was followed by UTP depletion to the minimum level within 60 to 90 min. This interval seems to be the most suitable time for sequential administration of 5-FUrd in chemotherapy. Experimental chemotherapy of intrahepaticItem Metadata only Studies of dose-and time-effect relationships of copper-induced oxidation of lipoproteins(Mahidol University. Mahidol University Library and Knowledge Center, 2024) Nanteetip Limpeanchob; Udom Chantharaksri; Yupin Sanvarinda; Supeenun Unchernof LDL following the incubation of native LDL with CuSO4 in vitro. The LDL was prepared by a sequential-density gradient ultracentrifugation method. The conjugated dienes and TBARS were measured as markers of oxidized LDL. CuSO4 in the doses varying from... to shift the dose-effect curve to the right. From the analysis of time-effect relationship, it always found that the effects on the formation of conjugated dienes preceeced that of TBARS, suggesting that formation of conjugated dienes was an preceeding step