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Item Metadata only Plasmodium falciparum : studies on antimalarial chalcone-chloroquine combination and development of fluorescence-bases antimalarial assay(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Nongluk Sriwilaijaroen; Prapon WilairatItem Metadata only Target guided synthesis of 5-Benzyl-2,4-diaminopyrimidine antimalarials(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Chawanee Sirichaiwat; Yodhathai Thebtaranonth.Item Metadata only Antimalarial activity of artemisinin : an iron-dependent mechanism of action(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Nathawut Sibmooh; Udom Chantharaksri; Jutamaad Satayavivad; Supeenun UnchernItem Metadata only Effects of antimalarial drugs and other stress factors on plasmodium falciparum In Vivo and In Vitro(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Navakanit Sachanonta; Emsri PongponratnItem Metadata only Stability of antimalarial activity of artesunate on adhesion properties of plasmodium falciparum-infected erythrocytes(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Busaba Pipitaporn; Rachanee Udomsangpetch; White Nicholas J.; Tada Sueblinvong; Kovit PattanapanyasatIn vitro assay was designed to determine stability of antimalarial activity; inhibition of parasite maturation including adherence properties, of artesunate readily dissloved in sodium bicarbonate solution. At 37 degree C, antimalarial activity... of artesunate 0.25 µg/ml decreased rapidly showing significant reduction after 2 weeks of storage. Whereas at 10 degree C or -20 degree C, drug could be stored more than 3 weeks or 7 months, respectively with no reduction in antimalarial activity. At lowerItem Metadata only Drug-parasite-host interaction action of artemisinin and its novel derivatives on Plasmodium falciparum(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Sumalee Kamchonwongpaisan; Yongyuth Yuthavong; Yodhathai Thebtaranonth; Prapon Wilairatwith parasite maturation; however, its antimalarial activity was highest at ring stage. The 50% inhibitory concentrations IC(,50) for the parasite in HbH/Hb Constant Spring red cells were decreased when normal red cells were added to the infected cells... accessibility to the parasite, which is decreased in infected variant red cells. Artemisinin is believed to exert its antimalarial activity through an oxidant mode. Its derivatives, therefore. Were developed on the basis of its requirement of ironItem Metadata only Synthesis of ethyl 2-alkyl-5-phenyl-6-oxa-1-azabicyclo [3.1.0] hexane-2-carboxylate derivatives and evaluation of their biological activities(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Nongpanga Ningsanont; Yodhathai ThebtaranonthItem Metadata only Development of novel anilinoacridine compounds directed at multiple targets in the malaria parasite, plasmodium falciparum(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Saranya Auparakkitanon; Wilai Noonpakdee; Prapon Wilairat; Porntip Petmitr.Item Metadata only Isolation and characterization of DNA polymerases and DNA topoisomerase II from Plasmodium falciparum(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Porntip Chavalitshewinkoon; Prapon Wilairat; Sakol Panyim; Thanit KusamranItem Metadata only Synthesis of endoperoxide of anthracene derivatives and their biological activities and chemistry of 4,6-dimethoxyindole derivatives : photooxidation and nitration(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Tinnagon Keawin; Shuleewan Rajviroongit