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Publication Metadata only The multi-faceted impact of methamphetamine on Alzheimer's disease: From a triggering role to a possible therapeutic use(2020-07-01) Mayuri Shukla; Bruno Vincent; Mahidol University; CNRS Centre National de la Recherche Scientifique© 2020 Elsevier B.V. Although it has been initially synthesized for therapeutic purposes and currently FDA-approved and prescribed for obesity, attention-deficit/hyperactivity disorder, narcolepsy and depression, methamphetamine became aPublication Open Access The utility of single-balloon enteroscopy for the diagnosis and management of small bowel disorders according to their clinical manifestations: a retrospective review(2013) Varayu Prachayakul; Morakod Deesomsak; Pitulak Aswakul; Somchai Leelakusolvong; Mahidol University. Siriraj Hospital. Department of Internal Medicineenteroscopy. However, the relative clinical advantages of the 2 methods remain controversial. This study therefore aimed to identify the indications for and therapeutic impact of performing single-balloon enteroscopy. Methods: We retrospectively reviewed.... Therapeutic procedures were performed in 11% of patients with GI bleeding and achieved a therapeutic yield of 14.6% with a minor complication rate of 11.7%. Conclusions: Single-balloon enteroscopy was effective for the diagnosis and treatment of small bowelPublication Metadata only The impact of a low dose, low volume, multi-site immunization on the production of therapeutic antivenoms in Thailand(2003-01-01) Supod Sriprapat; Surasak Aeksowan; Sompong Sapsutthipas; Charoonroj Chotwiwatthanakun; Porntip Suttijitpaisal; Ronachai Pratanaphon; Orawan Khow; Visith Sitprija; Kavi Ratanabanangkoon; Queen Saovabha Memorial Institute; Mahidol University; Chiang Mai UniversityTherapeutic antivenom against snakes was first produced by Albert Calmette in 1894. Since then antivenoms have saved the life of countless snakebite victims. However, there are still many problems associated with antivenom production, for examplePublication Metadata only Impact of septic shock hemodynamic resuscitation guidelines on rapid early volume replacement and reduced M(2010-12-01) Chairat Permpikul; Surat Tongyoo; Ranistha Ratanarat; Warakarn Wilachone; Aekarin Poompichet; Mahidol Universityof them achieved the therapeutic goal within 6 hours (86.8% vs. 44.4%, p < 0.001) and their hospital mortality was lower (41.2% vs. 69.4%, p = 0.008). When analyzing differences between those who survived and those who died, more of the surviving patients...,799 vs. 3,014.1 ± 1,579.9 ml, p = 0.038) and more of them achieved the therapeutic goal within 6 hours (95.5% vs. 55%, p < 0.001). Multivariate analysis of factors associated with mortality disclosed APACHE II score, volume resuscitation more than 800 mlPublication Metadata only Utility of adding SPECT/CT imaging to post-therapeutic radioiodine whole-body scan in patients with differentiated thyroid cancer(2015-01-01) Jiraporn Sriprapaporn; Chakmeedaj Sethanandha; Tawee Yingsa-Nga; Chulaluk Komoltri; Thonnapong Thongpraparn; Chompunoot Harnnanthawiwat; Mahidol University© 2015, Medical Association of Thailand. All rights reserved. Objective: To determine the usefulness of adding single-photon emission computed tomography/computed tomography (SPECT/CT) imaging to post-therapeutic radioiodine whole-body scan (Rx... first followed by evaluation of RxWBS plus SPECT/CT imaging. Foci of increased radioiodine uptake were identified and localization was attempted. The findings obtained from RxWBS were compared with WBS plus SPECT/CT imaging to determine impact on lesionPublication Metadata only Impact of Covid-19 on the therapeutic plasma exchange service within the South East Asian region: Consensus recommendations and global perspectives(2021-12-01) Shanthi Viswanathan; Fu Liong Hiew; Sasitorn Siritho; Metha Apiwattanakul; Kevin Tan; Amy M.L. Quek; Riwanti Estiasari; Rabani Remli; Shalini Bhaskar; Badrul M. Islam; Seinn Mya Mya Aye; Ohnmar Ohnmar; Thirugnanam Umapathi; Say Say Keosodsay; Nghia T.T. Hoang; Tianrong Yeo; Paul M. Pasco; National University Health System; Yangon General Hospital; Philippine General Hospital; Universitas Indonesia, RSUPN Dr. Cipto Mangunkusumo; Kuala Lumpur Hospital; National Neuroscience Institute of Singapore; Mahidol University; International Centre for Diarrhoeal Disease Research Bangladesh; Universiti Teknologi MARA; Universiti Kebangsaan Malaysia; Aryu International Hospital; Laos General Hospital; Neurological Institute of Thailand; Military Hospital 175Introduction: Therapeutic plasma exchange (TPE) for neuroimmunological disorders has played an increasingly important role within the Southeast Asian (SEA) region. The South East Asian Therapeutic Plasma exchange Consortium (SEATPEC) was formed... was conducted by SEATPEC member countries from January to June 2020 (Phase 1) and then from July 2020 to January 2021 in (Phase 2) to assess the impact of Covid-19 on regional TPE. Objectives: The study's main objectives were to explore the challengesPublication Metadata only Digital rectal examination, serum prostatic specific antigen or transrectal ultrasonography: The best tool to guide the treatment of men with benign prostatic hyperplasia(2009-01-01) Kittinut Kijvikai; Mahidol UniversityPurpose of review: Benign prostatic hyperplasia can be considered a progressive disease, and identifying men with progressive disease could have a significant impact on the decision to choose the different therapeutic options. Numerous pieces... of evidence demonstrate the impact of the prostate volume on the disease progression. It has been accepted that digital rectal examination, serum prostatic specific antigen and transrectal prostate ultrasound are the available tools for the prostate volumePublication Metadata only Impact of antiretroviral therapy on opportunistic infections of HIV-infected children in the therapeutic research, education and aids training asia pediatric HIV observational database(2014-01-01) Wasana Prasitsuebsai; Azar Kariminia; Thanyawee Puthanakit; Pagakrong Lumbiganon; Rawiwan Hansudewechakul; Fong Siew Moy; Matthew Law; Nagalingeswaran Kumarasamy; Kamarul Razali; Virat Sirisanthana; Annette H. Sohn; Kulkanya Chokephaibulkit; Mahidol University; The HIV Netherlands Australia Thailand Research Collaboration; University of New South Wales (UNSW) Australia; Chulalongkorn University; Khon Kaen University; Chiangrai Prachanukroh Hospital; Hospital Likas; YR Gaitonde Centre for AIDS Research and Education; Kuala Lumpur Hospital; Chiang Mai University; TREAT Asia/amfAR-The Foundation for AIDS Researchcountries and therefore reported findings may not be fully applicable to the pediatric HIV epidemic in Asia. METHODS: Retrospective and prospectively collected data from the Therapeutic Research, Education and AIDS Training Asia Pediatric HIV ObservationalPublication Metadata only The Impact of Serum Proteins and Surface Chemistry on Magnetic Nanoparticle Colloidal Stability and Cellular Uptake in Breast Cancer Cells(2019-02-01) Wid Mekseriwattana; Supreeya Srisuk; Ruttanaporn Kriangsaksri; Nuttawee Niamsiri; Kanlaya Prapainop; Mahidol University© 2019, American Association of Pharmaceutical Scientists. Superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively studied in biomedical applications for therapeutic or diagnostic purposes. Stability is one of the key determinants..., the importance of colloidal stability of SPIONs for utilizing in future therapeutic or diagnostic purposes is illustrated.Publication Metadata only Novel Analytical Platform For Robust Identification of Cell Migration Inhibitors(2020-12-01) Parinyachat Somchai; Kriengkrai Phongkitkarun; Patipark Kueanjinda; Supawan Jamnongsong; Kulthida Vaeteewoottacharn; Vor Luvira; Seiji Okada; Siwanon Jirawatnotai; Somponnat Sampattavanich; Faculty of Medicine, Khon Kaen University; Kumamoto University; Mahidol University; Faculty of Medicine, Siriraj Hospital, Mahidol University© 2020, The Author(s). Wound healing assay is a simple and cost-effective in vitro assay for assessing therapeutic impacts on cell migration. Its key limitation is the possible confoundment by other cellular phenotypes, causing misinterpretation... cell motility difference and extrinsic factors such as cell seeding density can significantly affect final interpretation of therapeutic impacts on cellular phenotypes. Such discrepancy can be rectified by using the actual wound closure time of each