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    End-tidal CO2 changes as predictors of significant blood pressure variations during general anesthesia
    (2025-12-01) Vijitpavan A.; Luengwattanakit K.; Srungboonmee K.; Vijitpavan A.; Mahidol University
    Purpose: This study aimed to establish thresholds for end-tidal CO2 (EtCO2) changes that indicate hemodynamic alterations occurring between intermittent blood pressure measurements. Given that EtCO2 reflects cardiac output under conditions of stable... with general anesthesia and controlled ventilation. EtCO2 and blood pressure were recorded every 3 min intraoperatively. Changes in EtCO2 (ΔEtCO2) between consecutive recordings were analyzed against corresponding percentage changes in systolic blood pressure
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    The effect of decreased respiratory compliance during pneumoperitoneum and the trendelenburg position on the reliability of end tidal carbon dioxide monitoring
    (2019-02-01) C. Pisitsak; P. Pinsem; C. Narritsirikul; M. Pisalayon; T. Virankabutra; Faculty of Medicine, Ramathibodi Hospital, Mahidol University
    in respiratory compliance can increase dead space ventilation; therefore, the gradient between PaCO 2 and ETCO 2 (PaCO 2 -PETCO 2 ) might be higher during pneumoperitoneum than at baseline. Materials and Methods: Twenty women who underwent laparoscopic... gynecological surgery were enrolled. Arterial blood gas samples were collected 10 minutes after induction of anesthesia (T0), 45 minutes after pneumoperitoneum and placement in the Trendelenburg position (T1), and after CO 2 desufflation and placement
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    Phrenic nerve stimulation for diaphragmatic pacing in a patient with high cervical spinal cord injury
    (2009-12-01) Bunpot Sitthinamsuwan; Sarun Nunta-aree; Mahidol University
    at the level of C2 had chronic central hypoventilation syndrome, requiring long-term use of a home ventilator. Preoperative end tidal CO 2 and tidal volume during spontaneous breathing indicated hypoventilation syndrome. Bilateral phrenic nerve stimulation... for diaphragmatic pacing was performed with spinal cord stimulators used for chronic pain. The end tidal CO2 pressure (ETCO2), tidal volume, and spontaneous breathing time have improved up to 29 months of postoperative follow-up period. Conclusion: Phrenic nerve
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    Perinatal Hemolytic Disorders and Identification Using End Tidal Breath Carbon Monoxide
    (2023-11-01) Christensen R.D.; Bahr T.M.; Pakdeeto S.; Supapannachart S.; Zhang H.; Mahidol University
    Hemolytic disorders can cause severe morbidity or can be life-threatening. Before the re-cent development of practical and inexpensive testing for hemolysis by quantifying carbon monoxide in end-tidal breath, some hemolytic disorders in perinatal... patients were not detected until se-verely problematic hyperbilirubinemia and/or anemia occurred. Here we review studies aimed at es-tablishing the normal reference intervals for end tidal breath carbon monoxide (ETCO) in various perinatal populations. We
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    Respiratory centre sensitivity and exercise tolerance in healthy Thais.
    (1990-07-01) N. Maranetra; S. Bovornkitti; Mahidol University
    -ventilation transfer and the two-minute walking test with rating of the breathing sensation on a visual analogue scale. Our results showed higher end-tidal Pco2 and tidal volume response to CO2 and less exercise tolerance in the elderly than in the young. Only... resistance and not the blunting of respiratory centre sensitivity, contributes principally to relative hypoventilation and exercise limitation in the elderly. The compensation, with high tidal volume response to CO2, seems ineffective in maintaining normo
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    Dead space ventilation in volume controlled versus pressure controlled mode of mechanical ventilation
    (2002-11-01) Apassorn Wathanasormsiri; Aroonwan Preutthipan; Teerachai Chantarojanasiri; Subharee Suwanjutha; Mahidol University
    by measuring the difference between arterial PCO2 and end-tidal PCO2 [P(a-ET)CO2]. From November 1996 to March 1997, 12 patients who were admitted to the pediatric intensive care unit and needed ventilator support for various reasons, were enrolled in the study.... Their ages ranged from 2 to 15 years. The mechanical ventilator (Benett 7200 or Servo 900C) setting during VD measurement i.e. tidal volume, inspiratory time and positive end expiratory pressure were kept constant between changing from pressure controlled
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    Predictors of perioperative complications in higher risk children after adenotonsillectomy for obstructive sleep apnea: A prospective study
    (2014-01-01) Anchana Thongyam; Carole L. Marcus; Justin L. Lockman; Mary Anne Cornaglia; Aviva Caroff; Paul R. Gallagher; Justine Shults; Joel T. Traylor; Mark D. Rizzi; Lisa Elden; University of Pennsylvania; Bangkok-Pattaya Hospital; Mahidol University
    as follows: apnea hypopnea index (rank-biserial correlation coefficient [r] = 0.174, P = .017), SpO2nadir (r = -0.332, P<.0005), sleep time with SpO2\90% (r = 0.298, P \.0005), peak end-tidal CO2(r = 0.354, P \.0005), and sleep time with end-tidal CO2.50 mm... complications. A model using age <3 years, SpO2nadir, and peak CO2predicted respiratory complications better than the American Academy of Pediatrics or American Academy of Otolaryngology-Head and Neck Surgery Foundation guidelines but was imperfect (area under
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    Endotracheal intubation with thiopental/succinylcholine or sevoflurane-nitrous oxide anesthesia in adults: A comparative study
    (2001-01-01) Arissara Iamaroon; Siriporn Pitimana-aree; Chatchai Prechawai; Jutarat Anusit; Kanchana Somcharoen; Onanong Chaiyaroj; Mahidol University
    % sevoflurane and 66% N2O in O2. At the loss of eyelash reflex, ventilation was assisted to establish end-tidal CO2between 25-30 mm Hg, and intubation was performed when end-tidal sevoflurane was approximately 6%. Criteria of jaw relaxation, vocal cords position
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    Association of intraoperative end-tidal CO2 levels with postoperative outcomes: a patient-level analysis of two randomised clinical trials
    (2025-01-01) Nasa P.; van Meenen D.M.P.; Paulus F.; Ferrando C.; Bluth T.; Gama de Abreu M.; Ball L.; Bossers S.M.; Schober P.; Schultz M.J.; Serpa Neto A.; Hemmes S.N.T.; Campos N.S.; Bluth T.; Hemmes S.N.T.; Librero J.; Pozo N.; Ferrando C.; Ball L.; Mazzinari G.; Pelosi P.; Gama de Abreu M.; Schultz M.J.; Neto A.S.; Hemmes S.N.T.; Gama de Abreu M.; Severgnini P.; Hollmann M.W.; Binnekade J.M.; Wrigge H.; Canet J.; Hiesmayr M.; Schmid W.; Tschernko E.; Jaber S.; Hedenstierna G.; Putensen C.; Pelosi P.; Schultz M.J.; Marti A.; Bacuzzi A.; Brodhun A.; Molin A.; Merten A.; Parera A.; Brunelli A.; Cortegiani A.; Güldner A.; Reske A.W.; Gratarola A.; Giarratano A.; Bastin B.; Heyse B.; Mazul-Sunko B.; Amantea B.; Barberis B.; Putensen C.; Uhlig C.; Marín C.M.; Celentano C.; La Bella D.; D'Antini D.; Velghe D.; Sulemanji D.; De Robertis E.; Hartmann E.; Montalto F.; Tropea F.; Mills G.H.; Cinnella G.; Della Rocca G.; Caggianelli G.; Pellerano G.; Mollica G.; Bugedo G.; Wrigge H.; Mulier J.P.; Vandenbrande J.; Geib J.; Yaqub J.; Florez J.; Mayoral J.F.; Sprung J.; Van Limmen J.; Bos L.D.J.; de Baerdemaeker L.; Jamaer L.; Spagnolo L.; Strys L.; Gil M.G.; Gama de Abreu M.; Vidal Melo M.F.; Schultz M.J.; Unzueta M.C.; Moral M.V.; Ferner M.; Hollmann M.W.; Weiss M.; Vanoni M.; Schaefer M.S.; Nasa P.; Mahidol University
    Background: The relationship between intraoperative end-tidal CO2 (etCO2) levels and postoperative outcomes remains unclear. We conducted a post hoc analysis of two randomised trials in adults undergoing major surgery under... general anaesthesia. Methods: We re-analysed individual participant data comparing high or low positive end-expiratory pressure with low tidal volume intraoperative ventilation using a merged database derived from two randomised trials in non-obese