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Publication Open Access การตอบสนองของผู้ป่วยมะเร็งที่ต้องรับรังสีรักษา และการรับรู้ต่อการให้ความรู้ และสนับสนุนเป็นรายบุคคลจากพยาบาล(2543) กรณิกา ตริชอบ; ปราณี ชวลิตสกุลชัย ลุนเบิร์ก; ปรียา ไพรัชเวทย์; Kornnika Trichorb; Pranee Chavalitsakulchai Lundberg; Preeya Pairatchvet; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี. ภาควิชารังสีวิทยาItem Open Access Establishment of 3D human microvessel-on-a-chip for investigation of inflammatory responses(Mahidol University, 2023) Thittaya Den-udom; Pimonrat Ketsawatsomkron; Kenjiro Muta; Nithi Asavapanumasmitigated the production of IL-6 induced by TNFα. Next, we investigated whether DHC elicited the same responses in 3D endothelial cell tubes. We first developed and characterized human capillary in a microfluidic device. Our human 3D capillary exhibited a...Capsaicin and dihydrocapsaicin (DHC) are the main pungent capsaicinoids derived from chili peppers. Capsaicin has been previously shown to reduce inflammatory responses and promotes vascular health by increasing nitric oxide (NO) productionItem Open Access The protection rights of the families of the terrorism suspects and convicts : looking further the government responsibility in protecting the terrorist’s family, the study case of bomb Bali I and bomb Bali II(Mahidol University, 2021) Aliyah Almas Saadah, 1997-; De Los Santos-sta, Amparita Maria; Padtheera NarkurairattanaIn Indonesia, terrorism is categorized as one of the extraordinary crimes, using the claim of fighting in the name of religion, as it has created various significant harms such as object destruction, human victims, physical trauma, political... of terrorism convicts and suspects experienced after the bombings, and how well the government protects those families from affording everyday life before. Secondly, policymakers, scholars, researchers, and human rights policy advocacy practitioners can usePublication Open Access Environmental Action is a Responsibility for a Viable Planet(2023) Naowarut Charoencais crucial to human survival but is often viewed as the responsibility of expert environmental health specialists. A compartmentalization of the environment into distinct parts (natural, human, physical, or biotic and abiotic) quickly falls apart when larger... change to the year 2100. Their findings suggest that things may get worse in coming decades with uncertainty about whether human actions can bring about enough change for ecosystem viability by 21002. Protecting the natural and built environmentsPublication Open Access Human Security and Human Rights : (Still) contested concepts in ASEAN(2015) Sriprapha Petcharamesree; ศรีประภา เพชรมีศรี; Mahidol University. Institute of Human Rights and Peace StudiesIf human rights is recognized and legalized by the ASEAN Charter, the term human security was not included. Not only been was it not included in the ASEAN Charter but it has also depoliticized. ASEAN is still reluctant to face the challenge... of balancing state and human security. Not only is ASEAN still facing challenges in balancing state security and human security, any arguments for strong conceptual links between human security and human rights, which has been recognized and mainstreamedPublication Open Access Responses of primary human nasal epithelial cells to EDIII-DENV stimulation: the first step to intranasal dengue vaccination(2016) Nattika Nantachit; Panya Sunintaboon; Sukathida Ubol; Mahidol University. Faculty of Science. Department of Microbiologyof vaccination. The tested immunogen was the domain III of dengue serotype-3 E protein (EDIII-D3) loaded into trimethyl chitosan nanoparticles (EDIII-D3 TMC NPs). The primary human nasal epithelial cells, HNEpCs, were used as an in vitro model for nasal... responses. Results: At tested concentrations, EDIII-D3 TMC NPs not only exerted no detectable toxicity toward HNEpC cultures but also efficiently delivered EDIII-D3 immunogens into HNEpCs. Moreover, HNEpCs quickly and strongly produced proinflammatoryItem Open Access Toll-like receptor-mediated immune response to dormancy-associated mycobacterium tuberculosis antigen Rv2659c(Mahidol University. Mahidol University Library and Knowledge Center, 2022) Chutiphon Saelee; Chaniya Leepiyasakulchai; Patchanee Chootong; Prasong Khaenamrequired to provide the better fusion proteins. While current research mainly focuses on the adaptive immune induction ability of vaccine candidates, the knowledge in innate immune response is still limited. This thesis characterized the potential ability... in stimulating innate immune response of the recombinant dormancy-associated Mtb protein Rv2659c. The immune recognition was significantly initiated at 400 ng/ml and 800 ng/ml of protein Rv2659c compared to the negative control in HEK-Blue™ hTLR2 and HEK-Blue™ hPublication Open Access Gender-Based Violence Prevention in Schools in Myanmar: A Study from Taunggyi(2021) Soe Thiri Win; Duanghathai Buranajaroenkij; Mahidol University. Institute of Human Rights and Peace Studiesof GBV among primary school teachers and the extent of GBV prevention in schools. This research examines forms of GBV occurring in Basic Education High schools in Taunggyi and explores teachers’ responses to GBV in schools from a human rights perspective... in schools, not only to ensure students’ safety in school and the surrounding environment but also to equip students with awareness of GBV by integrating it into the school curriculum. It is necessary to improve responses to GBV at the primary school levelPublication Open Access The Challenge of Bias in Human Rights Field Work Navigating the politics of human rights knowledge production(2021) Michael George Hayes; Mahidol University. Institute of Human Rights and Peace StudiesPublication Open Access Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation.(2014-07-09) Kwissa Marcin; Nakaya, Helder I.; Nattawat Onlamoon; Wrammert Jens; Villinger Francois; Perng, Guey Chuen; Sutee Yoksan; Kovit Pattanapanyasat; Kulkanya Chokephaibulkit; Ahmed Rafi; Pulendran Bali; Mahidol University. Faculty of Medicine Siriraj Hospital. Insitute of Molecular Biosciences; Mahidol University. Faculty of Medicine Siriraj Hospital. Department of Pediatricsare generated, we used a systems biological approach to analyze immune responses to dengue in humans. Transcriptomic analysis of whole blood revealed that genes encoding proinflammatory mediators and type I interferon-related proteins were associated with high...Dengue virus (DENV) infection induces the expansion of plasmablasts, which produce antibodies that can neutralize DENV but also enhance disease upon secondary infection with another DENV serotype. To understand how these immune responses