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Publication Open Access The Essential Rumi (Book Review)(2007) Richard John Hiam; Mahidol University. Research Institute for Languages and Cultures of Asia; Mahidol University. Institute of Language and Cultures for Rural DevelopmentPublication Open Access The complexity of languages and scripts used in Thailand’s deep south(2021) Uniansasmita Samoh; Suwilai Premsrirat; ยูเนียนสาสมีต้า สาเมาะ; สุวิไล เปรมศรีรัตน์; Mahidol University. Research Institute for Languages and Cultures of Asia; Mahidol University. Institute of Language and Cultures for Rural Developmentused increasingly with family, friends, and people in the community. Thai is also used as the medium of instruction in all government schools. Classical Malay (Jawi script) is used in the religious domain, especially in traditional Islamic education... and some signs. The Arabic language is used in teaching and learning Islamic studies in the Tadika, pondok and private Islamic schools as well as in some government schools. In addition, Arabic is used in studying the Qur’an and for writing the namesPublication Open Access Segmented Assimilation: A Comparison of the Factors Related to the Adjustment of Domestic and International Muslim Migrants to Bangkok(2015-01) Ford, Kathleen; Aree Jampaklay; Mahidol University. Institute for Population and Social Research, and 29% female international). The migrants also reported concerns about their future lives and difficulty with language. The Islamic faith and Islamic education were important factors in the adjustment of the migrants to Bangkok.Publication Open Access พฤติกรรมส่งเสริมสุขภาพด้านโภชนาการของผู้นำศาสนาอิสลาม จังหวัดยะลา(2558) ซูไมยะ เด็งสาแม; มณีรัตน์ ธีระวิวัฒน์; สุปรียา ตันสกุล; นิรัตน์ อิมามี; Sumaiyah Dengsamae; Manirat Therawiwat; Supreya Tansakul; Nirat Imamee; มหาวิทยาลัยมหิดล. คณะสาธารณสุขศาสตร์. ภาควิชาสุขศึกษาและพฤติกรรมศาสตร์This survey research aimed to study the promotion of nutritional behaviors by Islamic leaders in Yala Province. A randomized sample of 312 leaders was chosen by systematic sampling method, with districts selected first, followed by the selection..., and Pearson’s Product Moment Correlation. Results showed that participating Islamic leaders were between 36-86 years of age, 48.7 percent finished elementary school, and as to religious education, 36.5 percent finished “sanaweya” level. They had heldItem Open Access คุณลักษณะที่พึงประสงค์ของครูสอนศาสนาภาคบังคับ (ฟัรดูอีน) ของสมาคมคุรุสัมพันธือิสลามแห่งประเทสไทยในพระบรมราชูปถัมภ์(มหาวิทยาลัยมหิดล, 2564) อภิชาติ ประกอบผล; วุฒินันท์ กันทะเตียน; ปกรณ์ สิงห์สุริยา; อํานาจ ยอดทองThis study aimed to determine desirable characteristics of the Fardhu Ain teachers of the Islamic Relations Association of Thailand under the Royal Patronage of His Majesty the King, and to survey opinions on prioritization of desirable... characteristics to be improved in Fardhu Ain teachers of the Islamic Relations Association of Thailand. Qualitative data were collected through in-depth interviews with the President of the Islamic Relations Association of Thailand and other related threePublication Open Access Participants’ perceptions and understanding of a malaria clinical trial in Bangladesh(2014) Debashish Das; Cheah, Phaik Yeong; Fateha Akter; Dulal Paul; Akhterul Islam; Rasheda Samad; Ridwanur Rahman; Amir Hossain; Arjen Dondorp; Day, Nicholas P; White, Nicholas J; Mahtabuddin Hasan; Aniruddha Ghose; Ashley, Elizabeth A; Abul Faiz; Mahidol University. Faculty of Tropical Medicine. Mahidol-Oxford Tropical Medicine Research UnitBackground: Existing evidence suggests that there is often limited understanding among participants in clinical trials about the informed consent process, resulting in their providing consent without really understanding the purpose of the study, specific procedures, and their rights. The objective of the study was to determine the subjects’ understanding of research, perceptions of voluntariness and motivations for participation in a malaria clinical trial. Methods: In this study semi-structured interviews of adult clinical trial participants with uncomplicated falciparum malaria were conducted in Ramu Upazila Health Complex, in Bangladesh. Results: Of 16 participants, the vast majority (81%) were illiterate. All subjects had a ‘therapeutic misconception’ i.e. the trial was perceived to be conducted primarily for the benefit of individual patients when in fact the main objective was to provide information to inform public health policy. From the patients’ perspective, getting well from their illness was their major concern. Poor actual understanding of trial specific procedures was reported despite participants’ satisfaction with treatment and nursing care. Conclusion: There is frequently a degree of overlap between research and provision of clinical care in malaria research studies. Patients may be motivated to participate to research without a good understanding of the principal objectives of the study despite a lengthy consent process. The findings suggest that use of a standard consent form following the current ICH-GCP guidelines does not result in achieving fully informed consent and the process should be revised, simplified and adapted to individual trial settingsPublication Open Access การรับรู้ของผู้นำศาสนาอิสลามเกี่ยวกับพฤติกรรมการดูแลสุขภาพตามหลักปฏิบัติทางศาสนาของชาวไทยมุสลิมที่เป็นเบาหวานชนิดที่ 2 ระหว่างการถือศีลอดในเดือนรอมฎอน(2560) ซารินี มาซอ; พรทิพย์ มาลาธรรม; นุชนาฏ สุทธิ; Sarinee Masor; Porntip Malathum; Nuchanad Sutti; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี. โรงเรียนพยาบาลรามาธิบดีThe purpose of this descriptive study was to explore the perception of Islamic religious leaders toward religion-related health behavior of Thai Muslims with type 2 diabetes mellitus during the fasting month of Ramadan. Kleinman’s Explanatory... Model of Illness was used as the conceptual framework for the study in combination with Muslim beliefs. The sample was selected by purposive sampling which consisted of 40 Islamic religious leaders in Narathiwas Province, Thailand. Data were collectedPublication Open Access Blocking ERK1/2 signaling impairs TGF-β1 tumor promoting function but enhances its tumor suppressing role in intrahepatic cholangiocarcinoma cells(2017) Phaijit Sritananuwat; Natthaporn Sueangoen; Parichut Thummarati; Kittiya Islam; Tuangporn Suthiphongchai; Mahidol University. Faculty of Science. Department of Biochemistry; Mahidol University. Faculty of Medicine Ramathibodi HospitalBackground: Transforming growth factor-β (TGF-β) plays a paradoxical role in cancer: it suppresses proliferation at early stages but promotes metastasis at late stages. This cytokine is upregulated in cholangiocarcinoma and is implicated in cholangiocarcinoma invasion and metastasis. Here we investigated the roles of non-Smad pathway (ERK1/2) and Smad in TGF-β tumor promoting and suppressing activities in intrahepatic cholangiocarcinoma (ICC) cells. Methods: TGF-β1 efects on proliferation, invasion and migration of ICC cells, KKU-M213 and/or HuCCA-1, were investigated using MTT, colony formation, in vitro Transwell and wound healing assays. Levels of mRNAs and proteins/ phospho-proteins were measured by quantitative (q)RT-PCR and Western blotting respectively. E-cadherin localization was examined by immunofuorescence and secreted MMP-9 activity was assayed by gelatin zymography. The role of ERK1/2 signaling was evaluated by treating cells with TGF-β1 in combination with MEK1/2 inhibitor U0126, and that of Smad2/3 and Slug using siSmad2/3- and siSlug-transfected cells. Results: h-TGF-β1 enhanced KKU-M213 cell invasion and migration and induced epithelial-mesenchymal transition as shown by an increase in vimentin, Slug and secreted MMP-9 levels and by a change in E-cadherin localization from membrane to cytosol, while retaining the cytokine’s ability to attenuate cell proliferation. h-TGF-β1 stimulated Smad2/3 and ERK1/2 phosphorylation, and the MEK1/2 inhibitor U0126 attenuated TGF-β1-induced KKU-M213 cell invasion and MMP-9 production but moderately enhanced the cytokine growth inhibitory activity. The latter efect was more noticeable in HuCCA-1 cells, which resisted TGF-β-anti-proliferative activity. Smad2/3 knock-down suppressed TGF-β1 ability to induce ERK1/2 phosphorylation, Slug expression and cell invasion, whereas Slug knockdown suppressed cell invasion and vimentin expression but marginally afected ERK1/2 activation and MMP-9 secretion. These results indicate that TGF-β1 activated ERK1/2 through Smad2/3 but not Slug pathway, and that ERK1/2 enhanced TGF-β1 tumor promoting but repressed its tumor suppressing functions. Conclusions: Inhibiting ERK1/2 activation attenuates TGF-β1 tumor promoting efect (invasion) but retains its tumor suppressing role, thereby highlighting the importance of ERK1/2 in resolving the TGF-β paradox switch.Publication Open Access Local patriotism and the need for sound language and education policies in the border South(2012-05-03) Gothom Arya; Mahidol University. Research Center for Peace BuildingThe resurgence of violence in the border provinces southern of Thailand has many contributing factors. It is argued that the main factor is the combination of local patriotism and the sense of injustice. Local patriotism is particularly strong when local population speaks another language, practices another religion and has different historical narratives as compared to the national mainstream. Local patriotism is heightened and further sensitized when the population a the sense of solidarity as common victims of injustice while defending its patriotism. Local patriotism may or may not lead to separatism. For separatism to be viable as policy and feasible through militancy, there need to be international supports based on historical, legal or humanitarian grounds. Given the lack of such supports in the case of the border South, separatism exists as an ideology in the mind of a few who could not find a better answer in their strive to express their patriotism. Nevertheless, when combined with a sense of injustice, patriotism often leads to violent militancy which subverts the original aims in the pursuit of revenge and demand more autonomy. It is advocated that in solving the problem of violence in the border South, local people should be allowed greater participation in decision making especially on matters that may affect their patriotism. They should be allowed to defend their patrimony such as language, customary way of life, natural resources, education of their children etc. The language problem in the border South is discussed. Further language survey and research should be undertaken and participation of local population in the formulation of language policy is recommended.Item Open Access Jumma nation and persecution in Bangladesh(Mahidol University, 2021) Chakma, Jhubhur, 1994-; Saul, Rufin Jamey; Milos Hubinareligion and politics are used by the state to ensure their control of the region. The findings also unveil the mechanism of control and abuse used by the Muslim Bengali settlers, the Islamic fundamentalist quarters, and local ruling party leadership