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    ItemOpen Access
    A preliminary study on the prevalence of PSTEIN-BARR virus in oral cavity in a group of Thais
    (Mahidol University, 2022) Pasinee Vorakulpipat; Siribang-On Piboonniyom Khovidhunkit; Nakarin Kitkumthorn; Puangwan Lapthanasupkul
    Tobacco smoking, betel quid chewing, and alcohol consumption are risk factors for oral cancer (OC) and oral potentially malignant disorders (OPMDs). Epstein-Barr virus (EBV) has also been suggested as one of the etiological factors of oral
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    PublicationOpen Access
    ประสบการณ์การมีอาการและอิทธิพลของอาการต่อภาวะการทำหน้าที่ในผู้ป่วยมะเร็งระบบโลหิตวิทยาที่ได้รับยาเคมีบำบัด
    (2558) เนาวรัตน์ ซื่อดี; Naowarat Suedee; คนึงนิจ พงศ์ถาวรกมล; Kanaungnit Pongthavornkamol; อรวมน ศรียุกตศุทธ; Aurawamon Sriyuktasuth; นพดล ศิริธนารัตนกุล; Noppadol Siritanaratkul; มหาวิทยาลัยมหิดล. คณะพยาบาลศาสตร์; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์ศิริราชพยาบาล
    , and the Inventory Functional Status-Cancer. Descriptive statistics by frequency, percentage, mean, standard deviation, and predictive testing by multiple regression were used for data analysis. Main findings: The mean of symptom occurrences was 13 symptoms (range 3...-30; SD = 6.22), the most prevalent symptoms experienced by the sample were hair loss, lack of energy, dry mouth, numbness/tingling, and ‘I don’t look like myself ’. The most frequent symptoms were numbness/tingling, problems of urination, dry mouth
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    PublicationOpen Access
    Cancer Prevention lifestyle (Editorial)
    (2016) Jiraporn Chompikul; Mahidol University. ASEAN Institute for Health Development
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    PublicationOpen Access
    ภาวะน้ำลายแห้ง วิธีการจัดการ และผลลัพธ์ของผู้ป่วยมะเร็งศีรษะ และคอภายหลังได้รับรังสีรักษา
    (2553) ปิยวดี ขัดทะเสมา; พรรณวดี พุธวัฒนะ; ดรุณี ชุณหะวัต; Panwadee Putwatana; Piyawadee Kuthasema; Darunee Junhavat; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี. ภาควิชาพยาบาลศาสตร์
    The purpose of this descriptive research was to describe experiences of xerostomia, management and outcome, and their relationship in patients with head and neck cancer, post radiation. The symptom management model revised by Dodd and colleagues... was applied as the conceptual framework of the study. The participants included 100 patients with head and neck cancer who had received radiation, recruited by purposive sampling from Otolaryngology Department, and Department of Radiology, at a university
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    PublicationOpen Access
    ความสัมพันธ์ระหว่างความต้องการมีส่วนร่วมในการดูแล เพศ อายุ การรบกวนจากอาการและการรับรู้คุณภาพการดูแลของผู้ป่วยมะเร็งโลหิตวิทยาระหว่างรับการรักษาในโรงพยาบาล
    (2559) คนึงนิจ พงศ์ถาวรกมล; Kanaungnit Pongthavornkamol; พิจิตรา เล็กดํารงกุล; Pichitra Lekdamrongkul; นพดล ศิริธนารัตนกุล; Noppadol Siritanaratkul; ศิวะพร ศิริภูล; Siwaporn Siripoon; มหาวิทยาลัยมหิดล. คณะพยาบาลศาสตร์; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์ศิริราชพยาบาล
    Purpose: To investigate the relationships between patients’ preference for participation in care, gender, age, symptom burden, and perceived quality of care of hematological cancer patients during hospitalization. Design: Descriptive... correlational research. Methods: The study sample consisted of 50 hematological cancer patients who were admitted in one university hospital in Bangkok, Thailand. Subjects were recruited by purposive sampling. Data were collected using 1) Demographic
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    PublicationOpen Access
    ภาวะโภชนาการและปัจจัยที่มีผลต่อการบริโภคอาหารของผู้ป่วยระยะสุดท้าย ที่มารับบริการคลินิกดูแลและบรรเทาอาการ
    (2559) สุมนทิพย์ นาควิจิตร; กิติพล นาควิโรจน์; พรพิมล โอเจริญ; ศศปิรียากานต์ มิ่งวงศ์; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี. ภาควิชาเวชศาสตร์ครอบครัว
    of 51-60 years of age 30.1 per one-hundred, couple status 66 per one-hundred, universal health care user 48.5 per onehundred, house wife or unemployed 23 of one-hundred, those completed primary school 36.9 of onehundred, patients with lung cancer 32... of one-hundred, stomach and intestines and anus complications 15.5 per one-hundred, patients with liver cancer 6.8 per one-hundred, patients with acceptable weight 38.8 per one-hundred, patients with less than acceptable weight 31.1. The average calorie
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    PublicationOpen Access
    Antiproliferative activity against various cancer cells and phytochemical components of Thai herbal formula
    (2012) P. Rungrojtrakool; P. Siripong; Yahuafai, J; W. Chuakul; R. Temsiririrkkul; Wongsatit Chuakul; Rungrawee Temsiririrkkul; วงศ์สถิตย์ ฉั่วกุล; รุ่งระวี เต็มศิริฤกษ์กุล; Rungrawee Temsiririrkkul (e-mail: pyrtk@mahidol.ac.th); Mahidol University. Faculty of Pharmacy. Department of Pharmaceutical Botany; National Cancer Institute. Research Division. Natural Products Research Section
    Recently, cancer has become a major disease causing death of Thai people. Herbal formulas are complementary choices used for cancer treatment. In this study, a traditional herbal formula, which has been used for lung and liver cancer treatment..., was selected from Wang Nam Yen district in Sa Kaeo province. Aqueous extracts of the whole formula and of each component herb were investigated for antiproliferative activity by MTT colorimetric assay against four human cancer cells (KB, MCF-7, HepG2, Si
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    PublicationOpen Access
    End-of-study safety, immunogenicity, and efficacy of quadrivalent HPV (types 6, 11, 16, 18) recombinant vaccine in adult women 24-45 years of age.
    (2011-06-28) Castellsagué, X; Muñoz, N; Punnee Pitisuttithum; พรรณี ปิติสุทธิธรรม; Ferris, D; Monsonego, J; Ault, K; Luna, J; Myers, E; Mallary, S; Bautista, OM; Bryan, J; Vuocolo, S; Haupt, RM; Saah, A; Castellsagué, X; Mahidol University. Faculty of Tropical Medicine. Vaccine Trial Center.
    BACKGROUND: Previous analyses from a randomised trial in women aged 24-45 years have shown the quadrivalent human papillomavirus (qHPV) vaccine to be efficacious in the prevention of infection, cervical intraepithelial neoplasia (CIN), and external genital lesions (EGLs) related to HPV 6/11/16/18. In this report, we present end-of-study efficacy, safety, and immunogenicity data with a median follow-up time of 4.0 years. METHODS: We enrolled 3819 24-45-year-old women with no history of cervical disease or genital warts in the past 5 years. Women received quadrivalent vaccine or placebo at day 1, and at months 2 and 6. Ascertainment of CIN/EGL was accomplished through Pap testing, genital inspection, and cervicovaginal sampling (every 6 months). The main analysis was conducted in a per-protocol efficacy population (that received three doses, was naive to the relevant HPV types at day 1, and remained free of infection through month 7). Efficacy was also estimated in other naive and non-naive populations. RESULTS: Vaccine efficacy against the combined incidence of persistent infection, CIN/EGL related to HPV6/11/16/18 in the per-protocol population was 88.7% (95% CI: 78.1, 94.8). Efficacy for women who were seropositive and DNA negative for the relevant vaccine HPV type at the time of enrolment who received at least 1 dose was 66.9% (95% CI: 4.3, 90.6). At month 48, 91.5, 92.0, 97.4, and 47.9% of vaccinated women were seropositive to HPV 6/11/16/18, respectively. No serious vaccine-related adverse experiences were reported. CONCLUSIONS: The qHPV vaccine demonstrated high efficacy, immunogenicity, and acceptable safety in women aged 24-45 years, regardless of previous exposure to HPV vaccine type.
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    PublicationOpen Access
    Cigarette Plain Packaging Perceptions on Intent to Abstain from Smoking among Thai Female Youth
    (2019) Narumon Auemaneekul; Dusit Sujirarat; Pimpan Silpasuwan; Pratana Satitvipawee; Chukiat Viwatwongkasem; Malinee Sompopcharoen; Nithat Sirichotiratana; นฤมล เอื้อมณีกูล; ดุสิต สุจิรารัตน์; พิมพ์พรรณ ศิลปสุวรรณ; ปรารถนา สถิตย์วิภาวี; ชูเกียรติ วิวัฒน์วงศ์เกษม; มลินี สมภพเจริญ; นิทัศน์ ศิริโชติรัตน์; Mahidol University. Faculty of Public Health. Department of Public Health Nursing; Mahidol University. Faculty of Public Health. Department of Epidemiology; Mahidol University. Faculty of Public Health. Department of Biostatistics; Mahidol University. Faculty of Public Health. Department of Health Education and Behavioral Sciences; Mahidol University. Faculty of Public Health. Department of Public Health Administration
    This study examined the etiological model of cigarette plain packaging perception on intention to abstain from smoking among Thai female youth. The tested hypothesis proposed that the constructs of perception on plain packaging, perceivedsusceptibility and severity of smoking consequencesand fear arousal from salient health warnings will predict intent to abstain from smoking. Structural equation modeling (SEM) was used to analyze the data and variables were assessed using self-report questionnaires. Multistage stratified random samplingwas used to select subjects from both high schools and vocational schools in Bangkok. Random samplingof 15- to 24-year-old females was used to recruit a total of 438 subjects. The sample size included nonsmokers (86.3%), former smokers (5.48%) and smokers (8.22%). The SEM showed a good fit to the data (χ2= 1.060, df=2, P-value=0.589, CFI=0.999, TLI=0.999 and RMSEA<0.001, SRMR=0.005). In the SEM showed that smokers and former smoker had significantly negative associations with intent to abstain (β=-0.49 and-0.087, p<0.001 and 0.026) whileperceived severity and fear appeal were significantlypositive association with intent to abstain (β=0.237 and 0.124, p<0.001 and 0.003). Nonetheless, SEM revealed that the effect of perception on plain packaging, perceived severity and age of smoker and former smoker subjects on intent to abstain was partly mediated by fear arousal from salient health warnings. In addition, the effect of smokers on intent to abstain was also partly mediated by perceived severity.This information could be useful in designing interventions to promote abstinence from smoking among female youth and advocating and implementing the plain packaging policy in Thailand
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    PublicationOpen Access
    Antimicrobial and cytotoxic acetogenin from Polyalthia debilis
    (2015-03) Somchai Boonpangrak; Rungrot Cherdtrakulkiat; Ratchanok Pingaew; Patumporn Manam; Supaluk Prachayasittikul; Somsak Ruchirawat; Virapong Prachayasittikul; Mahidol University. Faculty of Medical Technology. Center for Innovation Development and Technology Transfer; Mahidol University. Faculty of Medical Technology. Department of Clinical Microbiology and Applied Technology; Mahidol University. Faculty of Medical Technology. Center of Data Mining and Biomedical Informatics
    activity against Morexella catarrhalis with the MIC of 64 microgram/mL, Corynebacterium diphtheriae NCTC 10356 and Streptococcus pyogenes with partial inhibition (50-75%) at 128 microgram/mL. The compound 1 exerted cytotoxic activity against 5 cancer cells