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Publication Open Access Paper-based Acetylcholinesterase Inhibition Assay Combining a Wet System for Organophosphate and Carbamate Pesticides Detection(2015-02-26) Amara Apilux; Chartchalerm Isarankura-Na-Ayudhya; Virapong Prachayasittikul; Tanawut Tantimongcolwat; Center for Innovation Development and Technology Transfer; Department of Clinical Microbiology and Applied TechnologyA dramatic increase in pesticide usage in agriculture highlights the need for on-site monitoring for public health and safety. Here, a paper-based sensor combined with a wet system was developed for the simple and rapid screeningPublication Open Access Energy Use and Consumption Patterns of Maize Cultivation - A Case Study in Thailand(2021) Sirikarn Thongmai; Thanakrit Neamhom; Withida Patthanaissaranukool; Supawadee Polprasert; Mahidol University. Faculty of Public Health. Department of Environmental Health Sciences; Mahidol University. Center of Excellence on Environmental Health and Toxicology (EHT)This study explored energy inputs and consumption patterns to determine energy and economical indices for maize cultivation in Thailand. To assess the energy performance of four used cropping systems, namely, highland cultivation in wet season (HLWS...), highland cultivation in dry season (HLDS), plains cultivation in wet season (PLWS), and plains cultivation in dry season (PLDS), data from energy consumed and produced show Net Energy Value (NEV) gains of +77.0, +106.5, +191.6, and +228.5 GJ/haPublication Open Access Effects of Climate Variability on the Annual and Intra-annual Ring Formation of Pinus merkusii growing in Central Thailand(2020) Nathsuda Pumijumnong; Kritsadapan Palakit; Mahidol University. Faculty of Environment and Resource Studies; Kasetsart University. Faculty of Forestry. Department of Forest Managementof maximum temperature in April and EQ SOIMarch indicated a decline during the previous century and an increase in this century. A multiple regression analysis indicated that the extreme maximum temperature, which declined at the beginning of the wet season... temperature at the beginning of the wet season indicated a rapid growth in P. merkusii, while the anomalous temperature declining at the beginning and increasing at the end of the wet season was the main factor inducing the intra-annual ring formationPublication Open Access Natural human Plasmodium infections in major Anopheles mosquitoes in western Thailand(2016) Patchara Sriwichai; Yudthana Samung; Suchada Sumruayphol; Kirakorn Kiattibutr; Chalermpon Kumpitak; Anon Payakkapol; Jaranit Kaewkungwal; Guiyun Yan; Liwang Cui; Jetsumon Sattabongkot; Mahidol University. Faculty of Tropical Medicine. Mahidol Vivax Research Unitpotential vector species all displayed apparent seasonality in relative abundance. While An. minimus s.l. was collected through the entire year, its abundance peaked in the season immediately after the wet season. In comparison, An. maculatus s.l. numbers... showed a major peak during the wet season. The two potential vector species, An. annularis s.l. and An. barbirostris s.l., both showed peak abundance during the transition from wet to dry season. Moreover, An. minimus s.l. was more abundant in indoorPublication Open Access Kinetic properties and stability of glucose dehydrogenase from Bacillus amyloliquefaciens SB5 and its potential for cofactor regeneration(2015) Thunyarat Pongtharangkul; Pattra Chuekitkumchorn; Nhuengtida Suwanampa; Panwajee Payongsri; Kohsuke Honda; Watanalai Panbangred; Mahidol University. Faculty of Science. Department of BiotechnologyGlucose dehydrogenases (GluDH) from Bacillus species offer several advantages over other NAD(P)H regeneration systems including high stability, inexpensive substrate, thermodynamically favorable reaction and flexibility to regenerate both NADH... tolerance towards n-hexane and its respective alcohols. The productivity of GluDH obtained in this study (8.42 mg-GluDH/g-wet cells; 1035 U/g-wet cells) was among the highest productivity reported for recombinant E. coli. With its low KM-value towardsPublication Open Access Effect of Fungus-Growing Termite on Soil CO2 Emission at Termitaria Scale in Dry Evergreen Forest, Thailand(2021) Warin Boonriam; Pongthep Suwanwaree; Sasitorn Hasin; Phuvasa Chanonmuang; Taksin Archawakom; Akinori Yamada; Mahidol University. Faculty of Environment and Resource Studies; Suranaree University of Technology. Institute of Science. School of Biology; Valaya Alongkorn Rajabhat University under the Royal Patronage. College of Innovative Management. Innovation of Environmental Management; Thailand Institute of Scientific and Technological Research. Expert Centre of Innovation Clean Energy and Environment; Royal Forest Department. Sakaerat Environmental Research Station; Tokyo Institute of Technology. Department of Biological Sciencesmounds of M. carbonarius were measured for CO2 efflux rates on their mounds and surrounding soils in dry and wet seasons. Also, measurement points were investigated for the active underground passages at the top 10% of among efflux rates. The mean ratePublication Open Access Comparative evaluation of hydroxypropyl cellulose and povidone in paracetamol tablet formulation(1993) Nuttanan Sinchaipanid; Ampol Mitrevej; ณัฐนันท์ สินชัยพานิช; อำพล ไมตรีเวชIt has been known hat capping and cost of production are the major problems in the manuhcture of paracetamol tablets. This study compared the binding property of hydroxypropyl cellulose (HPC) with that of povidone (PVP) in paracetamol tablet formulations. HPC-M and PVP-K90 were incorporated at 0.6% and l.0% dry basis. ln addition to paracetamol, binder and either corn starch, tapioca starch or pregelatinized starches were added. The granulations were lubricated with magnesium stearate. lt was found that, regardless of tre binder, corn starch and tapioca starch did not give acceptable tablets. Pregelatinized starches appeared to give better tablsts. At 0.6% level, HPC-M produced softer and slower disintegration tablets than did PVP-K90, while tre dissolutron seemed to be comparable. At 1.0% level, PVP-K90 gave better tablets as well. The study indicated hat PVP-K9O was superior to HPGM under this test conditions.Publication Open Access Impact of Climate Change on Reservoir Reliability: A Case of Bhumibol Dam in Ping River Basin, Thailand(2561) Allan Sriratana Tabucanon; Areeya Rittima; Detchasit Raveephinit; Yutthana Phankamolsil; Wudhichart Sawangphol; Jidapa Kraisangka; Yutthana Talaluxmana; Varawoot Vudhivanich; Wenchao Xue; Mahidol University. Faculty of Environment and Resource Studies; Mahidol University. Faculty of Engineering; Mahidol University. Faculty of Information and Communication Technology; Kasetsart University. Faculty of Engineering; Kasetsart University. Faculty of Engineering at Kamphaeng; Asian Institute of Technology. Department of Energy Environment and Climate Changethe inflow well (R2=0.70). Generally, the trend of increasing inflow amounts is expected to continue in the dry seasons from 2000-2099, while large fluctuations of inflow are expected to be found in the wet seasons, reflecting high uncertainties. In the case... to increased inflow amounts. The unmanageability occurs in the wet season, cautioning the need to redesign the rules.Item Open Access Development of taste masked fexofenadine hydrochloride orodispersible tablets using hot melt extrusion(2019) Nattawut Chareonthai; Thandar Aung; Keisuke Ueda; Kenjirou Higashi; Kunikazu Moribe; Satit Puttipipatkhachorn; สาธิต พุทธิพิพัฒน์ขจร; Mahidol University. Faculty of Pharmacy. Department of Manufacturing Pharmacy; Chiba University. Graduate School of Pharmaceutical SciencesOrodispersible tablet desired the oral solid formulations with a pleasant taste, and a rapid disintegration in the mouth with no need of water. In this study, orodispersible tablet formulations of fexofenadine HCl, a second generation anti-histamine drug were developed for pediatric and geriatric patients. To improve patient compliance, bitter taste masking using hot melt extrusion (HME) technology was studied. Fexofenadine HCl and Eudragit® EPO extruded powder at three different drug loadings (20%, 40% and 60%) was prepared by HME at various temperature (120°C, 150°C and 180°C). Physicochemical characterization using FT-IR spectroscopy, powder X ray diffraction and differential scanning calorimetry revealed that the amorphous state or molecularly dispersed state of fexofenadine HCl in HME powder was obtained at lower drug/polymer ratio and higher temperature. The HME powder extruded at 180°C was selected to prepare orodispersible tablet formulations. The orodispersible tablets with drug containing HME powder had physical properties conforming to pharmacopoeial standards, including weight variation, hardness, friability, disintegration time and drug dissolution in 0.1 N HCl. The taste masking performance using drug release test in simulated salivary fluid indicated that the orodispersible tablets had lower drug release, thus enabling taste masking effect in oral cavity. In conclusion, fexofenadine HCl orodispersible tablets with desired taste masked effect were successfully prepared by using hot melt extrusion technology.Publication Open Access The Effective ecological factors and vegetation at Koh Chang island, Trat province, Thailand(2013-01) Nathsuda Pumijumnong; Paramate Payomrat; นาฎสุดา ภูมิจำนงค์; Mahidol University. Faculty of Environment and Resource Studiesaccording to elevation and the topographic wetness index (TWI). Mixed plant communities were more likely to distribute in regions with moderate to low levels of TWI, which were divided by levels of elevation into lowland multi-aged stands (Type 1) or a