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Publication Metadata only Liver procollagen prolyl hydroxylase in Opisthorchis viverrini infected hamsters after praziquantel administration(1983-01-01) Nongporn Hutadilok; Witaya Thamavit; E. Suchart Upatham; Pintip Ruenwongsa; Mahidol University, the infected liver procollagen prolyl hydroxylase activity decreased after administration of praziquantel 300 mg kg-1body weight, and approached normal levels two weeks after treatment. In the infected hamsters, praziquantel, at a curative dose, caused aPublication Metadata only Effects of praziquantel and artesunate on the tegument of adult Schistosoma mekongi harboured in mice(2005-09-01) Wannee Jiraungkoorskul; Somphong Sahaphong; Prasert Sobhon; Suda Riengrojpitak; Niwat Kangwanrangsan; Mahidol Universitywith either 300 mg/kg praziquantel or 300 mg/kg artesunate. Mice were sacrificed 1 or 3 days post-treatment. Worms were collected by perfusion and examined by SEM. One to 3 days after administration of artesunate, the tegument of S. mekongi showed severe... swelling, vacuolization, fusion of the tegumental ridges and loss or shortening of the spines on the trabeculae, collapse and peeling. Praziquantel induced similar tegumental alterations as those observed after administration of artesunate, but they werePublication Metadata only Myricetin Possesses Anthelmintic Activity and Attenuates Hepatic Fibrosis via Modulating TGFβ1 and Akt Signaling and Shifting Th1/Th2 Balance in Schistosoma japonicum-Infected Mice(2020-04-16) Ping Huang; Minyu Zhou; Shaoyun Cheng; Yue Hu; Minzhao Gao; Yubin Ma; Yanin Limpanont; Hongli Zhou; Paron Dekumyoy; Yixin Cheng; Zhiyue Lv; Zhongshan School of Medicine, SYSU; Sun Yat-Sen University; Hainan Medical University; Mahidol University© Copyright © 2020 Huang, Zhou, Cheng, Hu, Gao, Ma, Limpanont, Zhou, Dekumyoy, Cheng and Lv. Schistosomiasis is a zoonotic and debilitating parasitic disease caused by Schistosoma japonicum. Praziquantel remains the choice for treating.... In addition, oral administration of myricetin in mice infected with S. japonicum showed a deworming effect in vivo, as evidenced by a significant reduction in the liver egg load. H&E staining, quantitative RT-PCR, and Western blotting assays showed