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Subject: Immunology and Microbiology

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Now showing 1 - 6 of 6
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    Individual feedback to reduce inappropriate antimicrobial prescriptions for treating acute upper respiratory infections in an outpatient setting of a Thai university hospital
    (2018-03-01) Pinyo Rattanaumpawan; Nuttagarn Chuenchom; Visanu Thamlikitkul; Faculty of Medicine, Siriraj Hospital, Mahidol University
    of Siriraj Hospital, Thailand. The aim of the study was to determine the effectiveness of individual feedback to reduce inappropriate antimicrobial prescriptions for treating URIs. The administrative ICD-10 database was used to identify index physicians... with at least one outpatient experience of URI. Data on antimicrobial prescriptions were extracted from the hospital pharmacy database. A confidential letter and SMS were sent to all index physicians about the extent of antimicrobial therapy they prescribed
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    Antimicrobial Stewardship in Tropical Infectious Diseases: Focusing on Dengue and Malaria
    (2022-08-01) Siribhadra A.; Ngamprasertchai T.; Rattanaumpawan P.; Lawpoolsri S.; Luvira V.; Pitisuttithum P.; Mahidol University
    . Dengue and malaria are common tropical infectious diseases requiring effective supportive treatment and antimalarial agents, respectively. The uncertainty of early diagnosis results in widespread empirical antimicrobial treatment in high -income as well... as in low-and middle-income countries. Although rapid diagnostic tests (RDTs) have been shown to limit antibiotic prescriptions in dengue and malaria, we observed a wide range of antibiotic prescriptions for 13–92.7% of cases in previous literature
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    Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens
    (2016-01-01) Sirijan Santajit; Nitaya Indrawattana; Mahidol University
    usage or prescription, inappropriate use of antimicrobials, and substandard pharmaceuticals. Understanding the resistance mechanisms of these bacteria is crucial for the development of novel antimicrobial agents or other alternative tools to combat... the known antimicrobial resistance mechanisms of ESKAPE pathogens.
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    Rationalizing antibiotic prescribing for bacterial pneumonia in patients with reported penicillin allergy—a qualitative study
    (2025-04-01) Lau X.M.N.; Zhu X.; Sidhu D.; Bay J.W.; Mo Y.; Tambyah P.A.; Lau X.M.N.; Mahidol University
    adverse effects, there are limited data on the rationale for the management of patients with bacterial pneumonia and concomitant penicillin allergy. Objectives: To investigate the rationale guiding antibiotic prescription for bacterial pneumonia patients... prescription decisions. More resources may be channelled into delabelling penicillin allergy to optimize patient outcomes.
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    A comparison of patients’ local conceptions of illness and medicines in the context of c-Reactive protein biomarker testing in chiang rai and yangon
    (2018-01-01) Yuzana Khine Zaw; Nutcha Charoenboon; Marco J. Haenssgen; Yoel Lubell; University of Oxford, Saïd Business School; London School of Hygiene & Tropical Medicine; Green Templeton College; Mahidol University; Nuffield Department of Clinical Medicine
    and medicines. Situated within the context of a clinical trial of C-reactive protein (CRP) biomarker testing to reduce antibiotic over-prescription at the primary care level, our study explores and compares the narratives of 58 fever patients in Chiang Rai...) at the primary care level in low- and middle-income country settings. We thereby go beyond the current knowledge about antimicrobial resistance and CRP POCT, which consists primarily of clinical research and quantitative data. We find that CRP POCT in Chiang Rai
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    Analysis of risk factors for a high prevalence of extended-spectrum β-lactamase-producing Enterobacteriaceae in asymptomatic individuals in rural Thailand
    (2011-05-01) Ulzii Orshikh Luvsansharav; Itaru Hirai; Marie Niki; Tadahiro Sasaki; Kiyoko Makimoto; Chalit Komalamisra; Wanna Maipanich; Teera Kusolsuk; Surapol Sa-Nguankiat; Somchit Pubampen; Yoshimasa Yamamoto; Osaka University Faculty of Medicine; Kobe University School of Medicine; Mahidol University
    . Stool samples and questionnaires obtained from 445 participants from three provinces in Thailand were analysed. The antimicrobial susceptibility of the isolates was assessed using phenotypic and genotypic methods. PCR analysis was performed to detect... the highest prevalence of ESBLproducing Enterobacteriaceae also had the highest prevalence of use and purchase of antibiotics without a prescription. Thus, this study revealed that faecal carriage of ESBL-producing Enterobacteriaceae is very high