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Item Metadata only Epigenetic regulation by metabolites from the gut microbiome(2022-01-01) Marín-Tello C.; Mahidol UniversityThe gut microbiome can metabolise food components, such as dietary fibres and various phytochemicals; and the microbiome can also synthesise some nutrients, for example B vitamins. The metabolites produced by bacteria and other micro-organisms in the colon can have implications for health and disease risk. Some of these metabolites are epigenetically active, and can contribute to changes in the chemical modification and structure of chromatin by affecting the activity and expression of epigenetically-active enzymes, for example histone deacetylases and DNA methyltransferases. The epigenetic activity of such gut microbiome metabolites is reviewed herein.Publication Metadata only Trace elements in marine sediment and organisms in the gulf of Thailand(2018-04-20) Suwalee Worakhunpiset; Mahidol University© 2018 by the author. Licensee MDPI, Basel, Switzerland. This review summarizes the findings from studies of trace element levels in marine sediment and organisms in the Gulf of Thailand. Spatial and temporal variations in trace element... concentrations were observed. Although trace element contamination levels were low, the increased urbanization and agricultural and industrial activities may adversely affect ecosystems and human health. The periodic monitoring of marine environmentsPublication Metadata only Distribution of the transposable element mariner in anopheline mosquitoes(2000-11-01) Mallika Imwong; Rosie Gail Sharpe; Pattamaporn Kittayapong; Visut Baimai; Mahidol University; University of LeedsWe have surveyed the distribution of the transposable element mariner using PCR in 23 species of Anopheles mosquitoes, including all of the most important vectors of malaria in South-east Asia. Sequencing of the nine positive species revealed... elements from the irritans, mauritiana and mellifera subfamilies. These are the first data showing the presence of three subfamilies of mariners in anophelines. The elements we encountered are likely to be inactive, based on the presence of multiple stopPublication Metadata only Ascaridoid nematode larvae in marine fishes from the Gulf of Thailand(1981-12-01) M. Bhaibulaya; Mahidol UniversityA total of 6624 marine fishes representing 51 species caught from the Gulf of Thailand were examined for larvae of ascaridoid nematodes and 232 specimens representing 23 species harboured 2 types of ascaridoid larva; Anisakis larva type IPublication Metadata only Surveillance of marine fish for ciguatera toxin at fish markets in Bangkok, Thailand(2014-01-01) Chirapol Sintunawa; Supaporn Wacharapluesadee; Abhinbhen Saraya; Thiravat Hemachudha; Faculty of Environment and Resource Studies, Mahidol University; King Chulalongkorn Memorial Hospital, Faculty of Medicine Chulalongkorn UniversityBackground: Ciguatera intoxication is a form of food poisoning. It is caused by the consumption of certain warm-water fish that have accumulated ciguatera toxin (CTX) through the marine food chain. Ciguatera fish poisoning (CFP) is a global disease..., which although common, has been largely ignored in Thailand. This may be attributed to lack of confirmatory tests and seemingly nonspecific clinical presentations. Objective: We studied CTX contamination in marine fish sold at Bangkok markets. Methods: APublication Metadata only Asperaculin A, a sesquiterpenoid from a marine-derived fungus, aspergillus aculeatus(2011-07-22) Nattha Ingavat; Chulabhorn Mahidol; Somsak Ruchirawat; Prasat Kittakoop; Chulabhorn Graduate Institute; Chulabhorn Research Institute; Mahidol UniversityA novel sesquiterpenoid, asperaculin A (1), possessing a novel [5,5,5,6]fenestrane ring system, was isolated from the marine-derived fungus Aspergillus aculeatus CRI323-04. The structure of asperaculin A (1) was established by analysisPublication Metadata only Transplantation of Macaca cynomolgus iPS-derived hematopoietic cells in NSG immunodeficient mice(2015-10-02) Soumeya Abed; Alisa Tubsuwan; Porntip Chaichompoo; In Hyun Park; Alice Pailleret; Aïssa Benyoucef; Lucie Tosca; Edouard De Dreuzy; Anais Paulard; Marine Granger-Locatelli; Francis Relouzat; Stéphane Prost; Gerard Tachdjian; Suthat Fucharoen; George Q. Daley; Emmanuel Payen; Stany Chrétien; Philippe Leboulch; Leïla Maouche-Chrétien; Universite Paris-Sud XI; Inserm; Universite Paris 7- Denis Diderot; Mahidol University; Children's Hospital Boston; Hopital Antoine Beclere; Brigham and Women's Hospital; Bluebird Bio, Inc.Publication Metadata only Rapid and accurate species-specific PCR for the identification of lethal Chironex box jellyfish in Thailand(2021-01-01) Nuankanya Sathirapongsasuti; Kasetsin Khonchom; Thunyaporn Poonsawat; Mitila Pransilpa; Supaporn Ongsara; Usawadee Detsri; Suwimon Bungbai; Sam ang Lawanangkoon; Worawut Pattanaporkrattana; Satariya Trakulsrichai; Ramathibodi Hospital; Thailand Ministry of Natural Resources and Environment; Faculty of Medicine Ramathibodi Hospital, Mahidol University; Phuket Marine Biological Center; Lower Andaman; Koh Kut Hospital; Central Gulf of Thailand; Koh Phangan Hospital; Southern Marine and Coastal Resources Research CenterBox jellyfish are extremely potent venom-producing marine organisms. While they have been found worldwide, the highest health burden has been anticipated to be the tropical Indo-Pacific of Southeast Asia (SEA). At least 12 Cubozoan species have nowPublication Metadata only AIDS-related discrimination in Asia(2005-05-01) Susan Paxton; G. Gonzales; K. Uppakaew; K. K. Abraham; S. Okta; C. Green; K. S. Nair; T. Parwati Merati; B. Thephthien; M. Marin; A. Quesada; La Trobe University; Pinoy Plus; Thai Network of People Living with HIV/AIDS; Indian Network of People Living with HIV/AIDS; Spiritia Foundation; State Institute of Urban Development; Universitas Udayana; Mahidol UniversityThe Asia Pacific Network of People Living with HIV/AIDS (APN+) conducted the first regional documentation of AIDS-related discrimination in Asia. This project was an action-based, peer-implemented study that aimed to develop an understanding of the nature, pattern and extent of AIDS-related discrimination in several Asian countries. Trained HIV-positive people interviewed 764 positive people in four countries (India 302; Indonesia 42; Thailand 338; the Philippines 82) using a structured questionnaire. Findings indicate that the major area of discrimination in each country is within the health sector, where over half of those surveyed experienced some form of discrimination. In all countries, the majority of people did not receive pre-test counselling before being tested for HIV. People who reported coerced testing were significantly more likely than other respondents to face subsequent AIDS-related discrimination. A considerable number of respondents were refused treatment after being diagnosed with HIV and many experienced delayed provision of treatment or health services. Breaches of confidentiality by health workers were common. Within the family and the community, women were significantly more likely to experience discrimination than men, including ridicule and harassment, physical assault and being forced to change their place of residence because of their HIV status. These findings have serious implications, particularly in light of the increasing trend in many countries to test all pregnant women in order to prevent transmission of HIV to their unborn children. © 2005 Taylor & Francis Group Ltd.Publication Metadata only Genetic differentiation of Anisakis species (Nematoda: Anisakidae) in marine fish Priacanthus tayenus from Gulf of Thailand(2018-09-01) P. Eamsobhana; H. S. Yong; S. L. Song; A. Tungtrongchitr; K. Roongruangchai; University of Malaya; Faculty of Medicine, Siriraj Hospital, Mahidol Universityseafood (fish or squid) infected with the larvae of this nematode. In the present study, anisakid nematodes collected from the marine fish Priacanthus tayenus (Purple-spotted big-eye) caught from the Gulf of Thailand were examined morphologically