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    Bone markers in the healthy Thai people
    (2011-10-01) Shutipen Buranasinsup; Arunee Jangsangthong; Narong Bunyaratavej; Mahidol University
    fragment (N-MID) and undercarboxylated osteocalcin (UcOC). The other bone formation markers are matrix Gla protein (MGP) and N-terminal propeptide of Type I collagen (P1NP) whereas the biomolecules using in determining the bone resorption comprises of C... formation and the increase of bone resorption. Both bone formation and resorption can be examined by the circulating biomolecules. The biomolecules using in determining the bone formation are composed of osteocalcin (OC) in form of Nterminal midmolecule
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    Efficacy of bisphosphonates evaluated by biological bone markers
    (2015-01-01) Narong Bunyaratavej; Nitaya Suwanawag; Mahidol University
    the treatment results and indicting whether the bisphosphonates have been properly used. The bone markers, formative marker, PINP showed a decrease in bone formation after 3 months; PINP = 38.51%. This is a good lesson to be learned, that bone formation hardly... ever occurs especially primary bone formation in cases where bisphosphonates is being taking. This study manifested the benefits of biological markers with quick response that can help the physicians treat the patients properly, save time and the cost
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    Thai traditional massage increases biochemical markers of bone formation in postmenopausal women: a randomized crossover trial
    (2013) Sunee Saetung; La-or Chailurkit; Boonsong Ongphiphadhanakul; Mahidol University. Ramathibodi Hospital. Department of Medicine
    markers of bone turnover. Methods: Forty-eight postmenopausal women participated in the study. All volunteers were randomized to a 2-hour session of Thai traditional massage twice a week for 4 weeks and a 4-week control period after a 2-week washout...). Conclusions: Thai traditional massage results in an increase in bone formation as assessed by serum P1NP, particularly in postmenopausal women who are older and have a smaller body build. Future studies with larger samples and additional design features
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    Biochemical markers of bone formation in Thai children and adolescents
    (2005-07-01) La Or Chailurkit; Umaporn Suthutvoravut; Pat Mahachoklertwattana; Somsri Charoenkiatkul; Rajata Rajatanavin; Faculty of Medicine, Ramathibodi Hospital, Mahidol University; Mahidol University
    reference ranges for biochemical markers should be established in a particular pediatric population. In this study, biochemical markers of bone formation, bone-specific alkaline phosphatase (BAP), and osteocalcin (OC) in healthy Thai children and adolescents... different patterns of changes in biochemical markers of bone formation. Copyright © 2005 Taylor & Francis, Inc.
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    Acute changes in biochemical markers of bone resorption and formation after Thai traditional massage
    (2010-07-01) Sunee Saetung; La or Chailurkit; Boonsong Ongphiphadhanakul; Mahidol University
    the statistically significant correlation disappeared between percentage change in bone turnover and the other sites of BMD. Conclusion: Thai traditional massage induces acute changes in bone formation and resorption markers. Study on the more prolonged effects... on the body in a rhythmic fashion. Objective: To explore the skeletal effect of Thai traditional massage by examining the changes in biochemical markers of bone turnover immediately after the massage. Material and Method: Subjects consisted of 30 healthy
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    Biochemical markers of bone turnover and response of bone mineral density to intervention in early postmenopausal women: An experience in a clinical laboratory
    (2001-06-11) L. O. Chailurkit; B. Ongphiphadhanakul; N. Piaseu; S. Saetung; R. Rajatanavin; Mahidol University
    Background: Markers of bone formation and resorption may be useful as early indicators of response to therapy. Our aim in this study was to investigate the use of bone markers for monitoring of intervention for bone loss in early postmenopausal... turnover appear to be of use in assessing early response to therapy. Bone resorption markers, especially serum CTx, are better indicators than bone formation markers for estimating the response to intervention in early postmenopausal women. However
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    Hypercalcemia and altered biochemical bone markers in post-bone marrow transplantation osteopetrosis: A case report and literature review
    (2012-08-01) Alisa Kulpiya; Pat Mahachoklertwattana; Samart Pakakasama; Suradej Hongeng; Preamrudee Poomthavorn; Mahidol University
    and bone resorption inhibitors, calcitonin, and bisphosphonate led to normalization of the serum calcium level. Bone resorption but not bone formation marker was persistently elevated despite having normocalcemia during a 16.5-month follow-up period. © 2011... is hypercalcemia that is a unique complication in this group of patients. We report a three-yr-old boy with osteopetrosis who developed hypercalcemia following the successful BMT. His maximal calcium level was 13.3 mg/dL. Markedly increased both bone formation
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    The action of Strontium ranelate: Myth or reality
    (2011-10-01) Narong Bunyaratavej; Mahidol University
    The present study aimed to show whether the Strontium ranelate was the dual action possessing either antiresorptive or formative properties. This retrograded study included 56 postmenopausal women using the biological bone turnover markers... antiresorptive nor formative actions and it was certainly not a dual action via the method of biological bone turnover markers.
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    Osteocalcin and bone-specific alkaline phosphatase in Asian elephants (Elephas maximus) at different ages
    (2015-01-01) Nlin Arya; Walasinee Moonarmart; Nareerat Cheewamongkolnimit; Nutcha Keratikul; Sawinee Poon-iam; Andrew Routh; Pitikarn Bumpenpol; Taweepoke Angkawanish; Mahidol University; Durrell Wildlife Conservation Trust; Thai Elephant Conservation Center under Royal Patronage
    . The aim of this study was to determine any relationship between the age of captive Asian elephants (Elephas maximus) and markers of bone formation.Serum samples from 24 female Asian elephants were collected to evaluate levels of two bone formation markers...© 2015 Elsevier Ltd. Bone turnover markers could offer a potential alternative means for the early diagnosis of metabolic bone disease in young growing elephants although the baseline of bone turnover markers in elephant is not well established
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    Practical experience in some aspects of bone markers.
    (2009-09-01) Narong Bunyaratavej; Mahidol University
    by the healthy young adult persons. The bone markers are essentially requested when diagnosing the bone state. Both formation and resorption markers represent bone turnover. The low values of bone markers are the signs of being low bone turnover as well...The biochemical bone markers are the firmly approved means for bone assessment with high accuracy for detecting the status of bone functions in real time. The values obtained from the bone markers are continuously fluctuating. The interpretation