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Item Metadata only Exploratory study on the chemistry of bromodifluoromethyl phenyl sulfide(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Nakin Surapanich; Vichai Reutrakul; Manat Pohmakotr; Chutima Kuhakarnปฏิกิริยาฟรีเดล‒คราฟ อัลคิลเลชันของ 1,2,4-ไตรเมทอกซีเบนซีน (239a) กับโบรโมไดฟลูออโร เมทิลเฟนิลซัลไฟด์ (41) โดยผ่านตัวกลาง 1,1-ไดฟลูออโร-1-เฟนิลซัลฟานิลเมทิล คาร์โบแคตไอออน (238) ทำให้ ได้ผลิตภัณฑ์หลายชนิดได้แก่ ไทโอเอสเทอร์ 104a, เบนโซฟีโนน 105a, ออร์โธไทโอเอสเทอร์ 241a, S,S-ไดเฟ นิลคาร์โบโนไดไทโอเอท (242) และ เฟนิล(2,4,5-ไตรเมทอกซีเฟนิล)ซัลแฟน(243a) ซึ่งชนิดของผลิตภัณฑ์ที่ ได้รับขึ้นอยู่กับสภาวะในการทำปฏิกิริยา นอกจากนี้เรายังได้แสดงให้เห็นว่า การทำปฏิกิริยาของ [(โบรโมไดฟลูออโรเมทิล)ซัลโฟนิล]เบนซีน กับ อนุพันธ์ของสไตรีน, ไวนิลอีเทอร์, และ เฮเทอโรอะโรมาติก สามารถทำได้ โดยใช้ตัวเร่งปฏิกิริยาพาล ลาเดียม ทำให้ประสบผลสำเร็จในการสังเคราะห์สารประกอบประเภท α-แอลคีนิล และ α-เฮเทอโรเอริล ที่ เชื่อมต่ออยู่กันหมู่ฟังก์ชัน α,α-ไดฟลูออโรเมทิลเฟนิลซัลโฟนPublication Metadata only Palladium-mediated heck-type reactions of [(Bromodifluoromethyl)sulfonyl] benzene: Synthesis of α-alkenyl- and α-heteroaryl-substituted α,α-difluoromethyl phenyl sulfones(2012-10-01) Nakin Surapanich; Chutima Kuhakarn; Manat Pohmakotr; Vichai Reutrakul; Mahidol UniversityPalladium-catalyzed Heck-type reactions of [(bromodifluoromethyl)sulfonyl] benzene (1) with styrene derivatives and heteroaromatic compounds successfully gave α-alkenyl- and α-heteroaryl-substituted α,α- difluoromethyl phenyl sulfones, respectively.... Palladium-catalyzed Heck-type reactions of [(bromodifluoromethyl)sulfonyl] benzene (1) are reported. Both styrene derivatives and heteroaromatic compounds gave PhSO 2 CF 2 -substituted products in moderate to good yields. © 2012 2012 Wiley-VCH Verlag GmbPublication Metadata only C-H Activation and Palladium Migration within Biaryls under Heck Reaction Conditions(2002-09-05) Gunter Karig; Maria Teresa Moon; Nopporn Thasana; Timothy Gallagher; University of Bristol; Chulabhorn Research Institute; Mahidol University(Equation Presented) Biaryl bromides such as 1 (R=NO2, H, OMe) undergo the Heck reaction to give both the expected products 3 ("retention") as well as "crossover" products 4 derived from a migration of Pd and net transfer of reactivity from one arylPublication Metadata only A new synthetic approach towards isoquinobenzazepinone and isoindolinobenzazepinone using acid-mediated cyclisation and Heck reaction(2009-01-03) Wong Phakhodee; Poonsakdi Ploypradith; Poolsak Sahakitpichan; Somsak Ruchirawat; Chulabhorn Research Institute; Mahidol University; The Institute of Science and Technology for Research and Development, Mahidol University. However, five-membered ring cyclisation of N-benzylbenzazepinone could be effected efficiently by employing the Heck reaction followed by catalytic hydrogenation to furnish the desired isoindolinobenzazepinone. © 2008 Elsevier Ltd. All rights reserved.Publication Unknown Heterogeneous Pd/POSS Nanocatalysts for C–C Cross-Coupling Reactions(2018-01-01) Vetiga Somjit; Michel Wong Chi Man; Armelle Ouali; Preeyanuch Sangtrirutnugul; Vuthichai Ervithayasuporn; ENSCM Ecole Nationale Supérieure de Chimie de Montpellier; Mahidol Universitywas also shown to be an efficient catalyst for Heck reactions. Simple catalyst recovery and reusability of PdNp@Bim-SQ for at least 5 catalytic cycles without loss of activity were also demonstrated.... an amorphous material of Pd(II)@Bim-SQ. Subsequent in situ reduction of Pd(II)@Bim-SQ during Suzuki−Miyaura cross-coupling reactions afforded monodispersed Pd nanoparticles (2.33 ± 1.50 nm) stablized on Bim-SQ support, PdNp@Bim-SQ with Pd loading up to 14% w/wPublication Unknown Synthesis of (+)-4-desoxypentenomycin and analogues(2010-08-13) Supakeat Kambutong; Chutima Kuhakarn; Patoomratana Tuchinda; Manat Pohmakotr; Mahidol University, Sonogashira, and Heck coupling reactions. © Georg Thieme Verlag Stuttgart.Item Unknown Synthesis of indolo- and benzothieno[3,2-c]quinolines via POCl3 mediated tandem cyclization of o-alkynylisocyanobenzenes derived from o-alkynyl-N-phenylformamides(2022-08-01) Uppalabat T.; Tapdara A.; Khaikate O.; Worakul T.; Surawatanawong P.; Leowanawat P.; Soorukram D.; Reutrakul V.; Meesin J.; Kuhakarn C.; Mahidol UniversityA synthesis of indolo[3,2-c]quinolines and benzothieno[3,2-c]quinolines has been developed employing o-alkynyl-N-phenylformamide derivatives as the substrates. The reaction proceeded via a tandem process involving POCl3-assisted intramolecular... cyclization of the firstly formed o-alkynylisocyanobenzenes, leading to the desired products in moderate to high yields. Furthermore, the reaction is efficient on a gram-scale and the products were structurally modified by amination, Suzuzki-Miyaura reactionPublication Unknown 9-vinylanthracene based fluorogens: Synthesis, structure-property relationships and applications(2017-12-01) Mengjie Liu; Sawaros Onchaiya; Lewis Yi Fong Tan; Mohammad A. Haghighatbin; Tracey Luu; Tze Cin Owyong; Roozbeh Hushiarian; Conor F. Hogan; Trevor A. Smith; Yuning Hong; La Trobe University; University of Melbourne; Mahidol Universityaggregation formation occurs. Here, we report a group of 9-position functionalized anthracene derivatives that were conveniently synthesized by the palladium-catalyzed Heck reaction. Using fluorometric analyses, these dyes were confirmed to show AIE behaviorItem Unknown Mono and Dumbbell Silsesquioxane Cages as Dual-Response Fluorescent Chemosensors for Fluoride and Polycyclic Aromatic Hydrocarbons(2022-02-14) Siripanich P.; Bureerug T.; Chanmungkalakul S.; Sukwattanasinitt M.; Ervithayasuporn V.; Mahidol UniversityPyrene-conjugated monomeric (2) and dimeric (5) shaped-silsesquioxane (SQ) cages, as chemical sensors for detecting fluoride and polycyclic aromatic hydrocarbons (PAHs), were prepared by Heck-coupling reactions between vinyl-functionalized SQ cagesPublication Unknown Potential risks and hazards from herbal uses(2014) Yuvadee Wongkrajang; Worawan Kitphati; Boontium Kongsaktrakoon; Rungravi Temsiririrkkul; ยุวดี วงษ์กระจ่าง; วรวรรณ กิจผาติ; บุญเทียม คงศักดิ์ตระกูล; รุ่งระวี เต็มศิริฤกษ์กุล; Yuvadee Wongkrajang; Mahidol University. Faculty of Pharmacy. Department of Physiology; Mahidol University. Faculty of Pharmacy. Department of Pharmaceutical BotanyThere are 7 types of potential risks and hazards from herbs, including allergic reactions, toxic reaction to liver and kidney, adverse effects, possible mutagenic effects, mistaken plants, contamination of heavy metals and adulterants mainly from