38 results
Search Results
Now showing 1 - 10 of 38
Publication Open Access ความสัมพันธ์ระหว่างพฤติกรรมการจัดการความขัดแย้งกับการบาดเจ็บของคู่สมรสในผู้ป่วยนอกเวชศาสตร์ครอบครัว(2554) สายสุนีย์ ทับทิมเทศ; สมจิต พฤกษะริตานนท์; ธราธิป พุ่มกำพล; Saisunee Tubtimtes; Somjit Prueksaritanond; Taratip Pumkompol; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี. ภาควิชาเวชศาสตร์ครอบครัวCouple conflict is a common problem in Thai families and it has impact on quality of life. The purpose of this study was to examine the relationship between conflict management behavior and injury of the couples in outpatients of a Family..., and denying the allegation. Both coping behaviors of attacking and beating with or without weapons were significantly associated with injuries. There were 14 of 272 subjects injured during the previous year. In brief, although the couple conflict couldPublication Metadata only Brain-kidney crosstalk(2014-06-05) Arkom Nongnuch; Kwanpeemai Panorchan; Andrew Davenport; Mahidol University; UCL Medical School; Bumrungrad International Hospitaltransporters predisposes to alterations in neurotransmitter secretion and uptake, coupled with drug accumulation increasing the risk of encephalopathy. On the other hand, acute brain injury can induce a variety of changes in renal function ranging from altered...Encephalopathy and altered higher mental functions are common clinical complications of acute kidney injury. Although sepsis is a major triggering factor, acute kidney injury predisposes to confusion by causing generalised inflammation, leadingItem Metadata only Application of short-wave infrared hyperspectral imaging combined with machine learning on chilling injury detection in fresh coriander(2025-06-01) Pipatsart N.; Meenune M.; Hoonlor A.; Niamsiri N.; Punyasuk N.; Mairhofer S.; Lertsiri S.; Pipatsart N.; Mahidol UniversityChilling injury in coriander (Coriandrum sativum L.) occurs easily during transportation at low temperatures and cold storage to maintain freshness, leading to quality deterioration. Such chilling injury is difficult to notice at the early stage... of the relevant wavelength in SWIR region was conducted prior to investigation of ML algorithms for effective classification of chilling injury. The early stage of chilling injury was explored with SWIR-HSI in comparison with conventional measurement of moistureItem Metadata only Neuroprotective effect of short-chain fatty acids against oxidative stress-induced SH-SY5Y injury via GPR43-dependent pathway(2023-01-01) Saikachain N.; Mahidol Universityof neurodegenerative disorders. Over the past few years, several studies have suggested that short-chain fatty acids, metabolites of the gut microbiota, might have a beneficial effect in neurodegenerative disorders. A G protein-coupled receptor 43 (GPR43) plays... line (SH-SY5Y) injury. Our findings suggest that a combination of short-chain fatty acids with a physiological function could protect neurons from H2O2-induced cell damage. The effect of short-chain fatty acids mixture was abolished by pretreatmentPublication Metadata only NF-κB is required for dengue virus NS5-induced RANTES expression(2015-01-01) Sasiprapa Khunchai; Mutita Junking; Aroonroong Suttitheptumrong; Suwattanee Kooptiwut; Guy Haegeman; Thawornchai Limjindaporn; Pa Thai Yenchitsomanus; Mahidol University; Faculty of Pharmaceutical Sciences© 2014 Elsevier B.V. Dengue virus (DENV) infection associates with renal disorders. Patients with dengue hemorrhagic fever and acute kidney injury have a high mortality rate. Increased levels of cytokines may contribute to the pathogenesis of DENV...-induced kidney injury. Currently, molecular mechanisms how DENV induces kidney cell injury has not been thoroughly investigated. Excessive cytokine production may be involved in this process. Using human cytokine RT2Profiler PCR array, 14 genes includingItem Metadata only GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt(2023-12-01) Moonwiriyakit A.; Yimnual C.; Noitem R.; Dinsuwannakol S.; Sontikun J.; Kaewin S.; Worakajit N.; Soontornniyomkij V.; Muanprasat C.; Mahidol UniversityBackground: Airway remodeling is associated with severity and treatment insensitivity in asthma. This study aimed to investigate the effects of G protein-coupled receptor 120 (GPR120) stimulation on alleviating allergic inflammation and remodelingItem Metadata only Label-free Electrochemical Immunosensor Toward IGFBP-7 Biomarker for Early Monitoring of Acute Kidney Injury(2026-01-01) Unson S.; Ruankham W.; Phopin K.; Tantimongcolwat T.; Unson S.; Mahidol UniversityInsulin-like growth factor-binding protein 7 (IGFBP-7) is a potential biomarker for early diagnosis of acute kidney injury (AKI). Herein, we have developed a novel label-free electrochemical immunosensor based on the self-assembly of 6-(ferrocenyl...)hexanethiol (Fc) and antibody-coupled L-cysteine on the gold nanoparticle-modified electrode (Ab/Fc-Au/SPCE) for sensitive detection of IGFBP-7 in urine. Fc was directly embedded on the electrode surface to serve as an intrinsic redox signal for the IGFBP-7Publication Metadata only Therapeutic targets for treatment of heart failure: Focus on GRKs and β-arrestins affecting βaR signaling(2018-11-27) Supachoke Mangmool; Warisara Parichatikanond; Hitoshi Kurose; Mahidol University; Kyushu Universityof the sympathetic nervous system is an adaptive neurohormonal response to acute myocardial injury and heart damage, whereas prolonged exposure to catecholamines causes defects in βAR regulation, including a reduction in the amount of βARs and an increase in βAR... desensitization due to the upregulation of G protein-coupled receptor kinases (GRKs) in the heart, contributing in turn to the progression of HF. Several studies show that myocardial GRK2 activity and expression are raised in the failing heart. Furthermore, βItem Metadata only The Development of Artificial Saliva with Oral Wound Healing Property(2024-01-01) Thaweboon S.; Srichan R.; Mala S.; Thaweboon B.; Thaweboon S.; Mahidol UniversityWound healing is a normal biological mechanism of the body that helps to maintain the integrity of the tissue. In this process, fibroblasts play an important role in supporting wound healing by migrating to the injury site and laying down a new.... The migration cells were fixed with 25% methanol and 0.2% toluidine blue. In vitro cell migration to the wound area was determined by photographing with an inverted microscope coupled to a digital camera (Nikon D 5100). In the presence of 0.25%, 0.5%, and 1% w/vPublication Open Access Synthesis of a “clickable” Angiopep-conjugated p-coumaric acid for brain-targeted delivery(2014-08-19) Thummaruk Suksrichavalit; Supaluk Prachayasittikul; Virapong Prachayasittikul; Chartchalerm Isarankura Na Ayudhya; Mahidol University. Faculty of Medical Technology. Center of Data Mining and Biomedical Informatics; Mahidol University. Faculty of Medical Technology. Department of Clinical Chemistry; Mahidol University. Faculty of Medical Technology. Department of Clinical Microbiology and Applied Technologyinjuries under oxidative stress are often limited to penetrate the blood–brain barrier (BBB). Angiopep-2 is the ligand of low-density lipoprotein receptor-related protein expressed on the BBB possessing high transcytosis capacity and parenchymal