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Publication Metadata only Characteristics of abnormal oral glucose tolerance test in GDM diagnosis and clinical correlation(2018-08-18) Nat Ketumarn; Dittakarn Boriboonhirunsarn; Faculty of Medicine, Siriraj Hospital, Mahidol University© 2017 Informa UK Limited, trading as Taylor & Francis Group. Objectives: To describe the characteristics of abnormal oral glucose tolerance test (OGTT) values at gestational diabetes mellitus (GDM) diagnosis and their associations with clinical... characteristics, and to evaluate the effect on GDM diagnosis if any OGTT value was omitted. Materials and methods: A cross-sectional study was conducted in 415 women diagnosed with GDM. The OGTT results were recorded and analyzed. Results: Of the 415 includedItem Open Access การให้คำแนะนำเพื่อการเตรียมตัวก่อนตรวจ 75 กรัม OGTT อย่างมีประสิทธิภาพ(2564) รติ ตันติวุฒิ; Rati Tantiwut; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี. ศูนย์การแพทย์สมเด็จพระเทพรัตน์ต่อกลูโคสตามเกณฑ์ คนปกติ ด้วยวิธีการตรวจ 75 กรัม OGTT (Oral glucose tolerance test) การให้คำแนะนำเพื่อการเตรียมตัวก่อนตรวจ 75 กรัม OGTT อย่างมี ประสิทธิภาพ จะช่วยให้ผู้ป่วยเตรียมตัวก่อนเข้ารับการตรวจได้อย่างถูกต้อง ผลการตรวจมีประสิทธิภาพไม่เกิดPublication Metadata only Beta-cell function in type 2 diabetic patients who failed to maintain good glycemic status with a combination of maximum dosages of metformin and sulfonylurea(2019-01-01) Tada Kunavisarut; Sutin Sriussadaporn; Raweewan Lertwattanarak; Faculty of Medicine, Siriraj Hospital, Mahidol Universityand metformin for 2 weeks and then underwent the first oral glucose tolerance test (OGTT), the Max-SU OGTT. After the Max-SU OGTT, SUs were discontinued for 4 weeks and the second OGTT, the Discont-SU OGTT, was performed. After the Discont-SU OGTT, the same SU... was restarted at 25% of the maximum dosage (25%Max-SU). After taking 25%Max-SU for 4 weeks, the third OGTT, the 25%Max-SU OGTT, was performed. Metformin at the same dosage was continued throughout the study. Normal OGTT (NGT) subjects, matched for age and bodyPublication Metadata only Predictive Value of 1 Hour 50g Oral Glucose Load Screening Test for Gestational Diabetes Mellitus Compared to 3 Hour Oral Glucose Tolerance Test in High Risk Pregnant Women(1993-01-01) Mayuree Jirapinyo; Gobchai Puavilai; Suwannee Chanprasertyotin; Somsak Tangtrakul; Mahidol University(3‐hr OGTT) in 396 high risk cases. Each patient, had 1‐hr GLT and 3‐hr OGTT performed in a separate week. Forty‐two cases (10.6%) who had abnormal 3‐hr OGTT were classified as gestational diabetes (GDM). One hundred and sixty cases (40.4%) had... an abnormal 1‐hr GLT (plasma glucose level ≥140 mg/dl). Thirty‐six of these 160 cases (22.5%) had an abnormal 3‐hr OGTT. In 236 women (59.6%) that had normal 1‐hr GLT (plasma glucose level <140 mg/dl) only 6 cases (2.5%) had an abnormal 3‐hr OGTT. If 1‐hrPublication Metadata only Effects of body mass on OGTT-derived insulin sensitivity indexes in healthy subjects(2004-12-01) Pornpimol Charoentong; Phornphop Naiyanetr; Chatchai Neatpisanvanit; Mahidol UniversitySeveral indexes have been proposed to quantify insulin sensitivity from fasting plasma glucose and plasma insulin levels as well as from the data obtained by the oral glucose tolerance test (OGTT). Obesity represents the major risk factor associatedItem Metadata only Beta cell function, incretin hormones, and incretin effect in obese children and adolescents with prediabetes(2022-03-01) Sakornyutthadej N.; Mahidol UniversityBackground: Defects of incretin hormones and incretin effect may be underlying mechanisms of abnormal glucose metabolism in youth. Objective: To assess incretin hormone dynamics during an oral glucose tolerance test (OGTT) and incretin effect... in obese children with prediabetes in comparison with those with normal glucose tolerance (NGT). Methods: Overweight and obese children were enrolled and classified according to OGTT results as NGT and prediabetes. Insulin sensitivity, insulin secretionPublication Metadata only Application of modified Watanabe's approach for reconstruction of insulin secretion rate during OGTT under non-constant fraction of hepatic insulin extraction(2013-05-28) Kiattiyot Juagwon; Yongwimon Lenbury; Andrea De Gaetano; Pasquale Palumbo; Mahidol University; South Carolina Commission on Higher Education; Universita Cattolica del Sacro Cuore, RomeIn this study, insulin and C-peptide concentration are used to assess the rate of insulin production. First, the data of insulin and C-peptide concentrations during OGTT are generated from an extended combined model (Watanabe et al., 1998). Two... extraction is not constant during OGTT, the modification of Watanabe's approach is necessary to accommodate variations in the fractional hepatic extraction. The modified approach proposed in this work is able to provide the accurate estimate of the ratePublication Metadata only Diagnosis of gestational diabetes mellitus: Comparison between national diabetes data group and carpenter- coustan Criteria(2014-01-01) Dittakarn Boriboonhirunsarn; Tripop Lertbunnaphong; Kamaitorn Tientong; Mahidol University© 2013 is published by the Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Background: A 100-g oral glucose tolerance test (OGTT) is commonly used to diagnose gestational diabetes mellitus (GDM). Carpenter-Coustan (CC) criteria.... Asian BiomedicineObjective: To evaluate the increase in the prevalence of GDM if CC criteria are applied to OGTT results, we compared findings with NDDG criteria. Pregnancy outcomes between women without GDM and those with GDM diagnosed by NDDG and CCPublication Metadata only Prediction of type 2 diabetes mellitus using fasting plasma glucose and HbA1c levels among individuals with impaired fasting plasma glucose: A cross-sectional study in Thailand(2020-11-10) Tullaya Sitasuwan; Raweewan Lertwattanarak; Faculty of Medicine, Siriraj Hospital, Mahidol University© 2020 Author(s). Objectives About 11%-30% of individuals with impaired fasting plasma glucose (IFG) have type 2 diabetes mellitus (T2DM), diagnosed by the 75 g oral glucose tolerance test (75 g OGTT). This study investigated (1) the prevalence... and cut-off levels for fasting plasma glucose (FPG) and glycated haemoglobin A1c (HbA1c) in IFG individuals that most effectively predict the presence of T2DM diagnosed by a 75 g OGTT; (2) the predictors associated with T2DM; and (3) the pathophysiologicalPublication Metadata only High prevalence of diabetes and abnormal glucose tolerance in Thai women with previous gestational diabetes mellitus(2017-09-01) Sirisawat Wanthong; Raweewan Lertwattanarak; Prasert Sunsaneevithayakul; Sutin Sriussadaporn; Sathit Vannasaeng; Apiradee Sriwijitkamol; Mahidol Universityof Obstetrics/Gynecology. 75 g-OGTT were performed in subjects without known diabetes. AGT was diagnosed using the American Diabetes Association criteria. Results The mean age, pre-gestational BMI, and time since delivery were 38 ± 5 years, 24.5 ± 5.7 kg/m2..., and 46 ± 26 months. Overall, 81% of the subjects had AGT, including IGT (38%), IGT + IFG (5%), T2DM (38%). Plasma glucose (PG) at 1 h after a 50 g-glucose challenge test (GCT), PG at 1 h after 100 g-OGTT, HbA1c, and HOMA-IR were significantly greater