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    A study on the thiamin status in [beta]-thalassemia : Hb E disease
    (Mahidol University. Mahidol University Library and Knowledge Center, 2023) Varaporn Kuslertjariya; Suthat Fucharoen; Bhinyo Panijpan
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    Erythrocyte transketolase activity in blood of mothers, umbilical cord and enwborn babies in thailand
    (1974-01-01) Panata Migasena; Supranee Changbumrung; Venus Supawan; Jiree Limtrakarn; Mahidol University; Women's Hosp.
    Simultaneous determinations of erythrocyte transketolase activity in maternal umbilical cord and newborn baby's blood of 60 full term healthy women from a low socioeconomic group of Bangkok were conducted. Forty-two percent of the women were found... to be deficient as judged from thiamine pyrophosphate (TPP) effect. The erythrocyte transketolase activities in umbilical cord and newborn baby's blood were significantly higher than those in maternal blood. During the neonatal period, the thiamine status
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    Transketolase and vitamin B1 influence on ROS-dependent neutrophil extracellular traps (NETs) formation
    (2019-01-01) Donporn Riyapa; Darawan Rinchai; Veerachat Muangsombut; Chayanin Wuttinontananchai; Mohammed Toufiq; Damien Chaussabel; Manabu Ato; Jenefer M. Blackwell; Sunee Korbsrisate; University of Cambridge; National Institute of Infectious Diseases; Mahidol University; Faculty of Medicine, Siriraj Hospital, Mahidol University; Telethon Kids Institute; Systems Biology and Immunology Department; Sidra Medicine
    oxygen species (ROS)-dependent cell death pathway participating in inflammation and autoimmune diseases. Transketolase (TKT) is a thiamine pyrophosphate (vitamin B1)-dependent enzyme that links the pentose phosphate pathway with the glycolytic pathway
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    Comparison of thiamin diphosphate high-performance liquid chromatography and erythrocyte transketolase assays for evaluating thiamin status in malaria patients without beriberi
    (2020-12-01) Andrew J. Taylor; Dinesh Talwar; Sue J. Lee; Lorna Cox; Mayfong Mayxay; Paul N. Newton; Glasgow Royal Infirmary; Mahosot Hospital, Lao; Mahidol University; Nuffield Department of Medicine; University of Health Sciences; MRC Elsie Widdowson Laboratory
    through the erythrocyte activation assay (ETKA) or basal transketolase activity (ETK), which indirectly measure thiamin diphosphate (TDP). Thiamin diphosphate can also be measured directly by high-performance liquid chromatography (HPLC), which may allow a
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    Effect of tea consumption on thiamin status in man
    (1974-01-01) S. L. Vimokesant; S. Nakornchai; S. Dhanamitta; D. M. Hilker; Mahidol University
    Studies were conducted in north Thailand to determine the effect of drinking tea and chewing tea leaves on the thiamin status of school children and adult villagers. Blood transketolase of the school children was determined after 7 day periods which... included: drinking tea instead of water, drinking tea plus thiamin supplement, thiamin supplement and no treatment. The transketolase thyamine pyrophosphate (TPP) effect was increased to deficient levels by drinking tea and decreased to normal by thiamin
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    Erythrocyte transketolase activity, markers of cardiac dysfunction and the diagnosis of infantile beriberi
    (2011-02-01) Douangdao Soukaloun; Sue J. Lee; Karen Chamberlain; Ann M. Taylor; Mayfong Mayxay; Kongkham Sisouk; Bandit Soumphonphakdy; Khaysy Latsavong; Kongsin Akkhavong; Douangkham Phommachanh; Vanmaly Sengmeuang; Khonsavanh Luangxay; Theresa McDonagh; Nicholas J. White; Paul N. Newton; Mahosot Hospital; Nuffield Department of Clinical Medicine; Mahidol University; MRC Human Nutrition Research; University of Health Sciences; Royal Brompton Hospital
    and activated erythrocyte transketolase activities (ETK) and activation (α) coefficients were assayed along with plasma brain natriuretic peptide, N-terminal pro-brain natriuretic peptide and troponin T. Basal ETK (and to a lesser extent activated ETK
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    Biochemical detection of thiamin deficiency in infants and children in Thailand
    (1974-12-01) B. Pongpanich; N. Srikrikkrich; S. Dhanamitta; A. Valyasevi; Mahidol University
    Erythrocyte transketolase activity and the effect of thiamine pyrophosphate stimulation were determined for 134 infants and children in Thailand. This study included 87 apparently healthy infants and children, 36 sick infants and children admitted... groups had biochemical evidence of thiamine deficiency, although there was no clinical evidence of beriberi. Measurement of thiamine pyrophosphate stimulation appears to be more specific than measurement of erythrocyte transketolase activity in confirming
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    Thiamine deficiency and malaria in adults from southeast Asia
    (1999-02-13) S. Krishna; A. M. Taylor; W. Supanaranond; S. Pukrittayakamee; F. Ter Kuile; K. M. Tawfiq; P. A.H. Holloway; N. J. White; Mahidol University; John Radcliffe Hospital; St George's University of London
    , 1992. We used the activation coefficient (α) for transketolase activity in erythrocytes to measure thiamine deficiency (defined as α > 1.31) in patients with severe and uncomplicated malaria and in controls (patients' relatives and healthy volunteers...). To exclude the possibility of interference in the assays, transketolase activity was also measured in erythrocytes used to culture parasites. Findings. 12 (52%) of 23 patients with severe malaria and ten (19%) of 54 patients with uncomplicated malaria had α
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    Clinically unapparent infantile thiamin deficiency in Vientiane, Laos.
    (2011-02-22) Khounnorath, Sengmanivong; Chamberlain, Karen; Taylor, Ann M.; Soukaloun, Douangdao; Mayxay, Mayfong; Lee, Sue J.; Phengdy, Bounthom; Luangxay, Khonsavanh; Sisouk, Kongkham; Soumphonphakdy, Bandit; Latsavong, Khaysy; Akkhavong, Kongsin; White, Nicholas J.; Newton, Paul N.; Newton, Paul N.; Mahidol University. Faculty of TropicalMedicine. Mahidol-Oxford Tropical Medicine Research Unit.
    /PRINCIPAL FINDINGS: A cohort of 778 sick infants admitted during one year without clinical evidence of beriberi were studied prospectively and erythrocyte transketolase assays (ETK) performed. Biochemical thiamin deficiency was defined both in terms
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    The vitamin B1, B2 and B6 status of school children in two resettlement areas in northeast Thailand
    (1976-12-01) W. H P Schreurs; P. Migasena; P. Pongpaew; Mahidol University
    The vitamin B 1 , B 2 and B 6 status of school children were studied in the Khon Kaen resettlement and irrigation area and in the Lam takong settlement in northeast Thailand using the in vitro tests based on the erythrocyte transketolase