Search Results

Now showing 1 - 10 of 175
  • Publication
    Sodium alginate-magnesium aluminum silicate composite gels: Characterization of flow behavior, microviscosity, and drug diffusivity
    (2007-09-07) Thaned Pongjanyakul; Satit Puttipipatkhachorn; Khon Kaen University; Mahidol University
    The aims of the present study were to characterize the flow behavior and thixotropic properties of sodium alginate-magnesium aluminum silicate (SA-MAS) composite gels with various ratios of SA and MAS, and to investigate the drug diffusivity... and microviscosity of the composite gels. Moreover, interaction of SA and MAS in the form of dry composite was examined by using Fourier Transform Infrared (FTIR), and a possible structure model of SA-MAS composite gel was illustrated. Incorporating MAS into the SA
  • Publication
    Investigation of novel alginate-magnesium aluminum silicate microcomposite films for modified-release tablets
    (2005-10-03) Thaned Pongjanyakul; Aroonsri Priprem; Satit Puttipipatkhachorn; Khon Kaen University; Mahidol University
    Physicochemical properties of sodium alginate-magnesium aluminum silicate (SA-MAS) composite films were investigated and a potential as a film former of SA-MAS dispersion for modifying drug release from tablets was evaluated as well. Interaction... between SA and MAS in the composite films was revealed using FTIR spectroscopy. Thermal behavior of the composite films was changed due to the complexation of SA and MAS. Powder X-ray diffractometry data suggested that a higher crystallinity
  • Item
    Avirulent, immunogenic flavivirus chimeras
    Natth Bhamarapravat; Mahidol University. Institute of Molecular Biosciences
  • Publication
    Chitosan-magnesium aluminum silicate composite dispersions: Characterization of rheology, flocculate size and zeta potential
    (2008-03-03) Wanwisa Khunawattanakul; Satit Puttipipatkhachorn; Thomas Rades; Thaned Pongjanyakul; Khon Kaen University; Mahidol University; University of Otago
    Composite dispersions of chitosan (CS), a positively charged polymer, and magnesium aluminum silicate (MAS), a negatively charged clay, were prepared and rheology, flocculate size and zeta potential of the CS-MAS dispersions were investigated. High... area of the composite dispersions. Microscopic studies showed that flocculation of MAS occurred after mixing with CS. The size and polydispersity index of the HCS-MAS flocculate were greater than those of the LCS-MAS flocculate. However, a narrower size
  • Publication
    Xanthan-alginate composite gel beads: Molecular interaction and in vitro characterization
    (2007-02-22) Thaned Pongjanyakul; Satit Puttipipatkhachorn; Khon Kaen University; Mahidol University
    Xanthan gum (XG), a trisaccharide branched polymer, was applied to reinforce calcium alginate beads in this study. Composite beads consisting of XG and sodium alginate (SA) were prepared using ionotropic gelation method. Diclofenac calcium-alginate... (DCA) beads incorporated with different amounts of XG were produced as well. Molecular interaction between SA and XG in the composite beads and the XG-DCA beads was investigated using FTIR spectroscopy. Physical properties of the XG-DCA beads
  • Publication
    Polymer-magnesium aluminum silicate composite dispersions for improved physical stability of acetaminophen suspensions
    (2009-04-08) Thaned Pongjanyakul; Satit Puttipipatkhachorn; Khon Kaen University; Mahidol University
    The aims of this study were to characterize the morphology and size of flocculates and the zeta potential and rheological properties of polymer-magnesium aluminum silicate (MAS) composite dispersions and to investigate the physical properties... of acetaminophen (ACT) suspensions prepared using the composite dispersions as a flocculating/suspending agent. The polymers used were sodium alginate (SA), sodium carboxymethylcellulose (SCMC), and methylcellulose (MC). The results showed that SA, SCMC, and MC
  • Publication
    Alginate-magnesium aluminum silicate composite films: Effect of film thickness on physical characteristics and permeability
    (2008-01-04) Thaned Pongjanyakul; Satit Puttipipatkhachorn; Khon Kaen University; Mahidol University
    The different film thicknesses of the sodium alginate-magnesium aluminum silicate (SA-MAS) microcomposite films were prepared by varying volumes of the composite dispersion for casting. Effect of film thickness on thermal behavior, solid-state... of the composite dispersion used in the preparation method could affect crystallinity and strength of the film surface and film bulk of the microcomposite films. This led to a change in water vapor and drug permeability of the films. © 2007 Elsevier B.V. All rights
  • Publication
    Enhanced enteric properties and stability of shellac films through composite salts formation
    (2007-11-01) Sontaya Limmatvapirat; Chutima Limmatvapirat; Satit Puttipipatkhachorn; Jurairat Nuntanid; Manee Luangtana-anan; Silpakorn University; Mahidol University
    The objective of this study was to improve the properties of shellac by composite salts formation. The shellac samples were prepared in various salt forms by dissolving them with 2-amino-2-methyl-1-propanol (AMP) and ammonium hydroxide (AMN..., optimized shellac properties could be easily accomplished by composite salts formation. © 2007 Elsevier B.V. All rights reserved.
  • Publication
    Municipal solid waste management in Phuntsholing city, Bhutan
    (2010-01-01) Norbu; Sittipong Dilokwanich; Usanee Uyasatian; Patompong Saguanwong; Bhutan Carbide and Chemicals Ltd; Faculty of Environment and Resource Studies, Mahidol University
    Municipal solid waste problem is a major concern in major cities in Bhutan. Despite the lack of reliable data on both waste composition and quantity, no studies have been conducted to identify problems and alternatives to improve the current system.... The study objectives are: 1) to determine solid waste composition and generation rate; and 2) to investigate current solid waste management system. Six waste samples were selected in Phuntsholing city from three designated collection spots and from three
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    Antimicrobial Efficiency and Chemical Composition of Jackfruit (Artocarpus heterophyllus Lam.) Extracts from Different Plant Parts
    (2025-03-28) Sutthisa W.; Sophachan H.; Pimvichai P.; Srisawad N.; Sutthisa W.; Mahidol University
    comprehensively evaluated the antimicrobial efficacy and chemical composition of its various plant parts. This study investigates the antimicrobial properties and chemical composition of 95% ethanol extracts from the bark, leaves, peel, and seeds of jackfruit