Journal Issue: JAAS Vol. 6 No. 1
Issued Date
2556
Resource Type
Language
tha
eng
eng
File Type
application/pdf
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
คณะสัตวแพทยศาสตร์ มหาวิทยาลัยมหิดล
Journal Volume
JAAS Volume 6
(2566)
Articles
Anthelminthic effects of artemisinin and its derivatives
(2013) Tawewan Tansatit; Mahidol University. Faculty of Veterinary Science. Department of Pre-clinic and Applied Animal Science
Qinghao (Artemisia annua, L.), a famous herb from China, has been used in traditional Chinese medicine.
Artemisinin, an active substance is extracted from the leaves and flowers of Qinghao, with a unique
sesquiterpene lactone endoperoxide structure showing an antimalarial activity. Derivatives of artemisinin,
artesunate and artemether, are the most widely used as antimalarial drugs. Since artemisinin not only possess
antimalarial properties, but also active against various parasitic infection. Ongoing research on these
compounds has been emphasized on the potential impact for anthelmintic treatment. Artemisinin derivatives
exhibited a broad spectrum property against various trematodes, nematode, and cestode both in vitro and
in vivo studies. These helminthocidal properties of artemisinin derivatives presented here provide further data
for clinical investigations in the field trial study. However, a better understanding of action of artemisinin
derivatives and their biomolecule target may contribute a promising possibility for clinical utility in
anthelmintic application. Toxicity of artemisinin derivatives was less and was demonstrated in experimental
animals with neurotoxicity and anemia.
การเปรียบเทียบผลสัมฤทธิ์ทางการเรียนของนักศึกษา คณะสัตวแพทยศาสตร์ มหาวิทยาลัยมหิดล ที่รับเข้าศึกษาในระบบโควตาและระบบกลางในปีการศึกษา 2553
(2556) นงลักษณ์ ปราบใหญ่; ปานวาด ปรียานนท์; ศิริกาญจน์ เรืองเอกลักษณ์; มหาวิทยาลัยมหิดล. คณะสัตวแพทยศาสตร์
This study aimed to compare academic achievement (GPAX) of the students in Faculty of Veterinary
Science, Mahidol University between the students who admitted by quota system and Central University
Admissions System (CUAS) in academic year 2010. The 254 students of the 1st-6th year were evaluated.
The data were analyzed by percentage, mean and standard deviation.
The results were presented as: 1) The academic achievement of the CUAS admitted students was higher
than the quota system admitted students in the 1st, 2nd, 4th and 6th year students. 2) The academic achievement of
the CUAS admitted students was higher than the quota system admitted students in the veterinary preparation
level whereas the academic achievement in pre-clinical and clinical levels of the quota system admitted students
was higher than the CUAS admitted students.
The Effect of adding L-Cysteine in Modified Kenny's extender on the quality of chilled stallion semen at 5oC
(2013) Panithi Sukho; Hiran Juwarahawong; Slitwan Sangiam; Kampon Kaeoket; Mahidol University. Faculty of Veterinary Science. Dapartment of Clinical Sciences and Public Health Department
The aim of this study was to investigate the effect of supplementation of L-Cysteine in Modified
Kenny's extender on chilled stallion semen quality at 5oC. Semen samples were collected from 3 stallions by
artificial vagina and centrifugation to remove seminal plasma and diluted with Modified Kenny's extender to
50 x 106 sperm/ml. Semen samples (n=10 ejaculates) were divided into 3 portions, the first portion as the control
(KE), the second portion was added with L-Cysteine 200 μmol/l (KEC200) and added L-Cysteine 400 μmol/l in
the last portion (KEC400). In all samples, the percentage of progressive motility, viability and acrosome
integrity were evaluated at 0, 24, 48 and 72 h after storage at 5oC. There were a significant (P < 0.05) lower
percentage of dead spermatozoa in group KE200 than other groups at 24 h. There was a significantly lower
percentage of progressive motility in KEC 400 compared toother groups at 48 h (P < 0.05). In addition, there
was a tendency (P = 0.1) of lower percentage of dead spermatozoa in group KE200 than other groups at 48 h.
At 72 h, comparing all groups, a higher percentage of viability in groups KEC200 and KEC400 was found,
but not statistically significant. In conclusion, Addition of L-cysteine at a concentration of 200 μmol/l to
the Modified Kenney's extender tend to improve the stallion chilled semen progressive motility, dead/alive,
viability and acrosome integrity during chilled storage at 5oC for 48 h.
Title
JAAS Vol. 6 No. 1
Author's Affiliation
มหาวิทยาลัยมหิดล. คณะสัตวแพทยศาสตร์