Publication: Metal-free regioselective direct thiolation of 2-pyridones
| dc.contributor.author | Kunita Phakdeeyothin | en_US |
| dc.contributor.author | Sirilata Yotphan | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2020-01-27T07:52:04Z | |
| dc.date.available | 2020-01-27T07:52:04Z | |
| dc.date.issued | 2019-01-01 | en_US |
| dc.description.abstract | © The Royal Society of Chemistry. A highly regioselective metal-free direct C-H thiolation of 2-pyridones with disulfides or thiols has been developed. A combination of persulfate and a commercially available halide source such as LiCl, NCS or I2 enables the successful direct incorporation of a sulfide moiety into the 5-position of pyridone under mild conditions, providing a useful and convenient approach for the preparation of a diverse array of 5-thio-substituted pyridones in moderate to excellent yields. | en_US |
| dc.identifier.citation | Organic and Biomolecular Chemistry. Vol.17, No.26 (2019), 6432-6440 | en_US |
| dc.identifier.doi | 10.1039/c9ob01061k | en_US |
| dc.identifier.issn | 14770520 | en_US |
| dc.identifier.other | 2-s2.0-85068380881 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/50303 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85068380881&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.title | Metal-free regioselective direct thiolation of 2-pyridones | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85068380881&origin=inward | en_US |