Publication:
The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. II. Effect of capsaicin upon intestinal Na<sup>+</sup>-K<sup>+</sup>-ATPase activities

Issued Date

1979-01-01

Resource Type

Article

ISSN

03784274

DOI

10.1016/0378-4274(79)90052-3

Other identifier(s)

2-s2.0-0018699755

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Toxicology Letters. Vol.4, No.5 (1979), 399-406

Suggested Citation

Yongyot monsereenusorn, Thirayudth Glinsukon The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. II. Effect of capsaicin upon intestinal Na<sup>+</sup>-K<sup>+</sup>-ATPase activities. Toxicology Letters. Vol.4, No.5 (1979), 399-406. doi:10.1016/0378-4274(79)90052-3 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/13283

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Title

The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. II. Effect of capsaicin upon intestinal Na<sup>+</sup>-K<sup>+</sup>-ATPase activities

Author(s)

Yongyot monsereenusorn
 Thirayudth Glinsukon

Other Contributor(s)

Mahidol University

Abstract

14.0 mg/100 ml capsaicin, incubated in everted sac preparations, produced no significant inhibition of intestinal Na + -K + -ATPase in the rat, but a 22.60% inhibition in the hamster. This differential effect was substantiated by in vitro studies of aliquots of crude mucosal homogenate. the ID 50 s for rat and hamster being 35.0 and 12.0 mg/100 ml, respectively. Capsaicin-induced-inhibition of intestinal glucose transport may be due in part to a secondary inhibitory effect on the ATPase dependent sodium pump. © 1979.

Keyword(s)

Pharmacology, Toxicology and Pharmaceutics

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URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/13283

Collections

Scopus 1969-1990