Publication: Antiinflammatory activity of flavonoids
Issued Date
1994-01-01
Resource Type
ISSN
09447113
Other identifier(s)
2-s2.0-85016784652
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Phytomedicine. Vol.1, No.2 (1994), 141-144
Suggested Citation
A. Panthong, D. Kanjanapothi, P. Tuntiwachwuttikul, O. Pancharoen, V. Reutrakul Antiinflammatory activity of flavonoids. Phytomedicine. Vol.1, No.2 (1994), 141-144. doi:10.1016/S0944-7113(11)80032-2 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/9540
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Title
Antiinflammatory activity of flavonoids
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Abstract
Fourteen flavonoids (flavones,- flavanones and chalcones) were assayed for oral antiinflammatory activity using carrageenan-induced hind paw edema in rats. The structural features necessary for antiinflammatory activity appear to be the presence of methoxyl groups at C5 and C7 of ring A and the pyrano ring B of the flavonoid molecule. Negligible or low antiinflammatory activities were found in the chalcone derivatives. The difference in the efficacy of the flavonoids tested possibly depends on their pharmacokinetic properties. © 1994, Gustav Fischer Verlag, Stuttgart · Jena · New York. All rights reserved.