Publication:
The excretion of polar metabolites of radioactive anhydroretinol in rabbit bile

Issued Date

1972-04-18

Resource Type

Article

ISSN

00052760

DOI

10.1016/0005-2760(72)90015-X

Other identifier(s)

2-s2.0-0015514717

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism. Vol.260, No.4 (1972), 666-669

Suggested Citation

P. Phuapradit, M. R. Lakshmanan, J. A. Olson The excretion of polar metabolites of radioactive anhydroretinol in rabbit bile. Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism. Vol.260, No.4 (1972), 666-669. doi:10.1016/0005-2760(72)90015-X Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10001

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Thesis

Title

The excretion of polar metabolites of radioactive anhydroretinol in rabbit bile

Author(s)

P. Phuapradit
 M. R. Lakshmanan
 J. A. Olson

Other Contributor(s)

Mahidol University

Abstract

After the intravenous administration of 10-24 mg of tritiated anhydroretinol in aqueous dispersion to rabbits, 12-16% of the dose was excreted in the bile within 10 h as water soluble, n-butanol-extractable highly polar metabolites. Anhydroretinol itself was not found in the bile. Three metabolites were detected by thin-layer chromatography on silica gel G, two with absorption maxima at 333, 349 and 368 nm and one with λ max of 350, 365 and 390 nm. At least one of the former components seems to be excreted as the β-glucuronide. © 1972.

Keyword(s)

Biochemistry, Genetics and Molecular Biology

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/10001

Collections

Scopus 1969-1990