Publication: Transition metal complexes of 8-aminoquinoline-5-substituted uracils with antioxidative and cytotoxic activities
| dc.contributor.author | Ratchanok Pingaew | en_US |
| dc.contributor.author | Apilak Worachartcheewan | en_US |
| dc.contributor.author | Veda Prachayasittikul | en_US |
| dc.contributor.author | Supaluk Prachayasittikul | en_US |
| dc.contributor.author | Somsak Ruchirawat | en_US |
| dc.contributor.author | Virapong Prachayasittikul | en_US |
| dc.contributor.other | Srinakharinwirot University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Chulabhorn Research Institute | en_US |
| dc.date.accessioned | 2018-10-19T04:34:36Z | |
| dc.date.available | 2018-10-19T04:34:36Z | |
| dc.date.issued | 2013-11-01 | en_US |
| dc.description.abstract | Metal complexes of 8-aminoquinoline (8AQ) derivatives were reported. This study presents a series of synthesized transition metal complexes of mixed ligands 8AQ-5-iodouracils (1-3) and 8AQ-5-nitrouracil (4-6) which have been investigated for their antioxidative and cytotoxic activities, as well as, powder X-ray diffraction patterns. Ni complex of 8AQ-5-nitrouracil (6) exerted significant cytotoxicity against MOLT-3 cell and superoxide scavenging activity. The results demonstrate an application of 8AQ molecule as a potential ligand for new bioactive compounds. ©2013 Bentham Science Publishers. | en_US |
| dc.identifier.citation | Letters in Drug Design and Discovery. Vol.10, No.9 (2013), 859-864 | en_US |
| dc.identifier.doi | 10.2174/15701808113109990004 | en_US |
| dc.identifier.issn | 1875628X | en_US |
| dc.identifier.issn | 15701808 | en_US |
| dc.identifier.other | 2-s2.0-84887864374 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/31175 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84887864374&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Transition metal complexes of 8-aminoquinoline-5-substituted uracils with antioxidative and cytotoxic activities | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84887864374&origin=inward | en_US |
