Publication:
ICSH recommendations for assessing automated high-performance liquid chromatography and capillary electrophoresis equipment for the quantitation of HbA<inf>2</inf>

Issued Date

2015-01-01

Resource Type

Article

ISSN

1751553X
17515521

DOI

10.1111/ijlh.12413

Other identifier(s)

2-s2.0-84941623803

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

International Journal of Laboratory Hematology. Vol.37, No.5 (2015), 577-582

Suggested Citation

A. D. Stephens, R. Colah, S. Fucharoen, J. Hoyer, D. Keren, A. Mcfarlane, D. Perrett, B. J. Wild ICSH recommendations for assessing automated high-performance liquid chromatography and capillary electrophoresis equipment for the quantitation of HbA<inf>2</inf>. International Journal of Laboratory Hematology. Vol.37, No.5 (2015), 577-582. doi:10.1111/ijlh.12413 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/35646

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Title

ICSH recommendations for assessing automated high-performance liquid chromatography and capillary electrophoresis equipment for the quantitation of HbA<inf>2</inf>

Author(s)

A. D. Stephens
 R. Colah
 S. Fucharoen
 J. Hoyer
 D. Keren
 A. Mcfarlane
 D. Perrett
 B. J. Wild

Other Contributor(s)

UCL
 Institute of Immunohaematology Mumbai
 Mahidol University
 Mayo Clinic
 University of Michigan, Ann Arbor
 Institute for Quality Management in Healthcare (IQMH)
 Barts and The London School of Medicine Charterhouse Square
 Hammersmith Hospital

Abstract

© 2015 John Wiley & Sons Ltd. Automated high performance liquid chromatography and Capillary electrophoresis are used to quantitate the proportion of Hemoglobin A<inf>2</inf> (HbA<inf>2</inf>) in blood samples order to enable screening and diagnosis of carriers of β-thalassemia. Since there is only a very small difference in HbA<inf>2</inf> levels between people who are carriers and people who are not carriers such analyses need to be both precise and accurate. This paper examines the different parameters of such equipment and discusses how they should be assessed.

Keyword(s)

Biochemistry, Genetics and Molecular Biology

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/35646

Collections

Scopus 2011-2015