Publication: Generation of a human induced pluripotent stem cell line (MUi010-A) from skin fibroblast of patient carrying a c.2104C>T mutation in MYH9 gene
| dc.contributor.author | Amornrat Tangprasittipap | en_US |
| dc.contributor.author | Bunyada Jittorntrum | en_US |
| dc.contributor.author | Praguywan Kadegasem | en_US |
| dc.contributor.author | Werasak Sasanakul | en_US |
| dc.contributor.author | Nongnuch Sirachainan | en_US |
| dc.contributor.author | Narisorn Kitiyanant | en_US |
| dc.contributor.author | Suradej Hongeng | en_US |
| dc.contributor.other | Faculty of Medicine, Ramathibodi Hospital, Mahidol University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2020-01-27T07:46:25Z | |
| dc.date.available | 2020-01-27T07:46:25Z | |
| dc.date.issued | 2019-04-01 | en_US |
| dc.description.abstract | © 2019 Mutations in MYH9 gene is one of the major causes of inherited thrombocytopenia resulted from nonfunctional myosin-9 protein. We have generated a human induced pluripotent stem cell line MUi010-A from skin fibroblasts of a patient who had a point mutation c.2104C>T (p.R702C) in the exon 16 of MYH9 gene using a non-integrative reprogramming method. The MUi010-A exhibited embryonic stem cell-like characteristics with consistent pluripotent markers expression, was capable of all three embryonic germ layers differentiation, and had a normal karyotype. | en_US |
| dc.identifier.citation | Stem Cell Research. Vol.36, (2019) | en_US |
| dc.identifier.doi | 10.1016/j.scr.2019.101397 | en_US |
| dc.identifier.issn | 18767753 | en_US |
| dc.identifier.issn | 18735061 | en_US |
| dc.identifier.other | 2-s2.0-85061823358 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/50207 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85061823358&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.title | Generation of a human induced pluripotent stem cell line (MUi010-A) from skin fibroblast of patient carrying a c.2104C>T mutation in MYH9 gene | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85061823358&origin=inward | en_US |