Publication: Dioscorealides and dioscoreanone, novel cytotoxic naphthofuranoxepins, and 1,4-phenanthraquinone from Dioscorea membranacea Pierre
| dc.contributor.author | Arunporn Itharat | en_US |
| dc.contributor.author | Anuchit Plubrukarn | en_US |
| dc.contributor.author | Palangpon Kongsaeree | en_US |
| dc.contributor.author | Tam Bui | en_US |
| dc.contributor.author | Niwat Keawpradub | en_US |
| dc.contributor.author | Peter J. Houghton | en_US |
| dc.contributor.other | King's College London | en_US |
| dc.contributor.other | Prince of Songkla University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-07-24T03:19:13Z | |
| dc.date.available | 2018-07-24T03:19:13Z | |
| dc.date.issued | 2003-08-07 | en_US |
| dc.description.abstract | (Matrix presented) Commonly used among ingredients in Thai traditional anticancer preparations, the rhizome of Dioscorea membranacea Pierre was found potently cytotoxic and possibly contributed to such a therapeutic effect. Bioassay-guided isolation resulted in two novel cytotoxic naphthofuranoxepins, dioscorealides A (1) and B (2), and a new 1,4-phenanthraquinone, dioscoreanone (3). The structure determination, achieved mainly by means of NMR and CD spectral and X-ray crystallographic analyses, and cytotoxicity are discussed here. | en_US |
| dc.identifier.citation | Organic Letters. Vol.5, No.16 (2003), 2879-2882 | en_US |
| dc.identifier.doi | 10.1021/ol034926y | en_US |
| dc.identifier.issn | 15237060 | en_US |
| dc.identifier.other | 2-s2.0-0141631703 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/20702 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0141631703&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.title | Dioscorealides and dioscoreanone, novel cytotoxic naphthofuranoxepins, and 1,4-phenanthraquinone from Dioscorea membranacea Pierre | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0141631703&origin=inward | en_US |