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Depsidones and an α-pyrone derivative from Simpilcillium sp. PSU-H41, an endophytic fungus from Hevea brasiliensis leaf

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dc.contributor.authorPraphatsorn Saetangen_US
dc.contributor.authorVatcharin Rukachaisirikulen_US
dc.contributor.authorSouwalak Phongpaichiten_US
dc.contributor.authorSita Preedanonen_US
dc.contributor.authorJariya Sakayarojen_US
dc.contributor.authorSuparerk Borwornpinyoen_US
dc.contributor.authorSawinee Seemakhanen_US
dc.contributor.authorChatchai Muanprasaten_US
dc.contributor.otherPrince of Songkla Universityen_US
dc.contributor.otherThailand National Center for Genetic Engineering and Biotechnologyen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-12-21T06:23:53Z
dc.date.accessioned2019-03-14T08:02:15Z
dc.date.available2018-12-21T06:23:53Z
dc.date.available2019-03-14T08:02:15Z
dc.date.issued2017-11-01en_US
dc.description.abstract© 2017 Elsevier Ltd Nine previously undescribed depsidones (simplicildones A-I) and one previously undescribed α-pyrone (simplicilopyrone) were isolated from the endophytic fungus Simplicillium sp. PSU-H41 along with 11 known compounds. Their structures were established by extensive spectroscopic analysis. Simplicildone A and known botryorhodine C displayed weak antibacterial against Staphylococcus aureus with equal MIC values of 32 μg/mL. Additionally, botryorhodine C was active against methicillin-resistant S. aureus with the same MIC value. Simplicildone C exhibited weak antifungal activity against Cryptococcus neoformans with an MIC value of 32 μg/mL. In addition, simplicildones A and C and botryorhodine C were noncytotoxic against noncancerous Vero cells.en_US
dc.identifier.citationPhytochemistry. Vol.143, (2017), 115-123en_US
dc.identifier.doi10.1016/j.phytochem.2017.08.002en_US
dc.identifier.issn00319422en_US
dc.identifier.other2-s2.0-85026908528en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/41309
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85026908528&origin=inwarden_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleDepsidones and an α-pyrone derivative from Simpilcillium sp. PSU-H41, an endophytic fungus from Hevea brasiliensis leafen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85026908528&origin=inwarden_US

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