Publication: Impaired interaction of α-haemoglobin-stabilising protein with α-globin termination mutant in a yeast two-hybrid system
dc.contributor.author | Chairat Turbpaiboon | en_US |
dc.contributor.author | Thawornchai Limjindaporn | en_US |
dc.contributor.author | Wiyada Wongwiwat | en_US |
dc.contributor.author | Yaowalak U-Pratya | en_US |
dc.contributor.author | Noppadol Siritanaratkul | en_US |
dc.contributor.author | Pa Thai Yenchitsomanus | en_US |
dc.contributor.author | Sarawut Jitrapakdee | en_US |
dc.contributor.author | Prapon Wilairat | en_US |
dc.contributor.other | Mahidol University | en_US |
dc.date.accessioned | 2018-08-20T07:20:08Z | |
dc.date.available | 2018-08-20T07:20:08Z | |
dc.date.issued | 2006-02-01 | en_US |
dc.description.abstract | α-Thalassaemia caused by α-globin gene termination codon mutations (αT-globin) has been explained by their inherent mRNA instability and by oxidative damage arising from the presence of membrane-bound αT-globin chains. To better understand the latter phenomenon, a yeast two-hybrid system was used to assay the interaction between αT-globin and its molecular chaperone, α-haemoglobin- stabilising protein (AHSP) and impaired binding of αT-globin with AHSP compared with αwild-type-globin was observed. © 2005 Blackwell Publishing Ltd. | en_US |
dc.identifier.citation | British Journal of Haematology. Vol.132, No.3 (2006), 370-373 | en_US |
dc.identifier.doi | 10.1111/j.1365-2141.2005.05865.x | en_US |
dc.identifier.issn | 13652141 | en_US |
dc.identifier.issn | 00071048 | en_US |
dc.identifier.other | 2-s2.0-33644868959 | en_US |
dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/23824 | |
dc.rights | Mahidol University | en_US |
dc.rights.holder | SCOPUS | en_US |
dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33644868959&origin=inward | en_US |
dc.subject | Medicine | en_US |
dc.title | Impaired interaction of α-haemoglobin-stabilising protein with α-globin termination mutant in a yeast two-hybrid system | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | |
mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33644868959&origin=inward | en_US |