Journal of the Medical Association of Thailand. Vol.56, No.11 (1973), 634-644
Suggested Citation
V. Suvatte, S. Tuchinda L asparaginase treatment in acute leukemia of childhood. Journal of the Medical Association of Thailand. Vol.56, No.11 (1973), 634-644. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10166
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L asparaginase treatment in acute leukemia of childhood
The results of the combination of L asparaginase and prednisolone for the induction of remission in acute leukemia of childhood were reported. A complete remission was achieved in 12 (75%) out of 16 cases of acute lymphoblastic leukemia within two weeks and in 2 (40%) out of 5 cases of acute myeloblastic leukemia. Serious side effects were few, many biochemical disturbances were observed, but these were well tolerated and reversible. The combination of prednisolone to L asparaginase may reduce the incidence of hypersensitivity reactions.
