Publication: Biomonitoring for arsenic, toxic and essential metals in single hair strands by laser ablation inductively coupled plasma mass spectrometry
Issued Date
2011-10-01
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ISSN
13873806
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2-s2.0-80052964496
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Mahidol University
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SCOPUS
Bibliographic Citation
International Journal of Mass Spectrometry. Vol.307, No.1-3 (2011), 185-191
Suggested Citation
Usarat Kumtabtim, Andreas Matusch, Sergio Ulhoa Dani, Atitaya Siripinyanond, J. Sabine Becker Biomonitoring for arsenic, toxic and essential metals in single hair strands by laser ablation inductively coupled plasma mass spectrometry. International Journal of Mass Spectrometry. Vol.307, No.1-3 (2011), 185-191. doi:10.1016/j.ijms.2011.03.007 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/11696
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Title
Biomonitoring for arsenic, toxic and essential metals in single hair strands by laser ablation inductively coupled plasma mass spectrometry
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Abstract
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has been developed as reliable analytical technique for the quantitation of metal distributions at micrometre resolution. In this work a novel microanalytical strategy for biomonitoring of arsenic, toxic and essential metals in single hair strands is proposed. Two different calibration strategies in LA-ICP-MS were developed using either certified hair standard reference material (IAEA 086) or prepared matrix-matched laboratory hair standards doped with analytes of interest at defined concentration. Powdered hair standards and human hair strands mounted on a sticky tape in the LA chamber were analyzed under the same experimental conditions by an optimized LA-ICP-MS technique. The use of hair powder standard allows calibration curves to be obtained by plotting the analyte ion (M + ) intensity normalized to 34 S + (the ratio M + / 34 S + ) as a function of the concentration determined by ICP-MS of acidic digests. The linear correlation coefficients (R) of calibration curves for analytes As, Ba, Cd, Ce, Co, Cr, Cu, Fe, Ga, Hg, Mg, Mo, Ni, Pb, Rb, Sr,Ti and U were typically between 0.985 and 0.999. The limit of detection (LOD) was 0.6 μg g -1 for As and ranged from 0.3 to 7.8 μg g -1 for the other analytes. Distinct elemental exposition time profiles were observed in hair samples from five volunteers. © 2011 Elsevier B.V.