Publication: Cytotoxic sesquiterpenes from luminescent mushroom Neonothopanus nambi
| dc.contributor.author | Somdej Kanokmedhakul | en_US |
| dc.contributor.author | Ratsami Lekphrom | en_US |
| dc.contributor.author | Kwanjai Kanokmedhakul | en_US |
| dc.contributor.author | Chariya Hahnvajanawong | en_US |
| dc.contributor.author | Sureeporn Bua-Art | en_US |
| dc.contributor.author | Weerasak Saksirirat | en_US |
| dc.contributor.author | Samran Prabpai | en_US |
| dc.contributor.author | Palangpon Kongsaeree | en_US |
| dc.contributor.other | Khon Kaen University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-06-11T04:33:40Z | |
| dc.date.available | 2018-06-11T04:33:40Z | |
| dc.date.issued | 2012-09-30 | en_US |
| dc.description.abstract | Four new aristolane sesquiterpenes named nambinones A-C (1-3) and 1-epi-nambinone B (4), a new sesquiterpene, nambinone D (5), a known compound, aurisin A (6) as well as a new dimeric sesquiterpene, aurisin K (7), were isolated from two isolates of luminescent mushroom, Neonothopanus nambi, PW1 and PW2. These structures were established on the basis of spectroscopic evidence. The relative configuration of 6 was determined by X-ray crystallographic analysis. Compounds 6 and 7 exhibited antimalarial activity against Plasmodium falciparum and antimycobacterial activity against Mycobacterium tuberculosis. Compounds 3, 6, and 7 showed cytotoxicity against NCI-H187 cancer cell lines. In addition, 6 and 7 showed cytotoxicity against the cholangiocarcinoma cell lines. © 2012 Elsevier Ltd. All rights reserved. | en_US |
| dc.identifier.citation | Tetrahedron. Vol.68, No.39 (2012), 8261-8266 | en_US |
| dc.identifier.doi | 10.1016/j.tet.2012.07.057 | en_US |
| dc.identifier.issn | 14645416 | en_US |
| dc.identifier.issn | 00404020 | en_US |
| dc.identifier.other | 2-s2.0-84865064882 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/13608 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84865064882&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Cytotoxic sesquiterpenes from luminescent mushroom Neonothopanus nambi | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84865064882&origin=inward | en_US |