Publication: Release of granzymes and chemokines in Thai patients with leptospirosis
| dc.contributor.author | M. De Fost | en_US |
| dc.contributor.author | W. Chierakul | en_US |
| dc.contributor.author | R. Limpaiboon | en_US |
| dc.contributor.author | A. Dondorp | en_US |
| dc.contributor.author | N. J. White | en_US |
| dc.contributor.author | T. Van Der Poll | en_US |
| dc.contributor.other | Academic Medical Centre, University of Amsterdam | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Udon Thani Regional Hospital | en_US |
| dc.contributor.other | University of Oxford | en_US |
| dc.date.accessioned | 2018-08-24T02:13:06Z | |
| dc.date.available | 2018-08-24T02:13:06Z | |
| dc.date.issued | 2007-01-01 | en_US |
| dc.description.abstract | The plasma concentrations of granzymes are considered to reflect the involvement of cytotoxic T-cells and natural killer cells in various disease states. Interferon (IFN)-γ-inducible protein-10 (IP-10) and monokine induced by IFN-γ (Mig) are members of the non-ELR CXC chemokine family that act on T-cells and natural killer cells. This study revealed that the plasma concentrations of granzyme B (but not granzyme A), IP-10 and Mig were higher in 44 Thai patients with definite or possible leptospirosis than in healthy blood donors. These data suggest that activation of cell-mediated immunity is part of the early host response to leptospirosis. © 2007 European Society of Clinical Microbiology and Infectious Diseases. | en_US |
| dc.identifier.citation | Clinical Microbiology and Infection. Vol.13, No.4 (2007), 433-436 | en_US |
| dc.identifier.doi | 10.1111/j.1469-0691.2006.01640.x | en_US |
| dc.identifier.issn | 14690691 | en_US |
| dc.identifier.issn | 1198743X | en_US |
| dc.identifier.other | 2-s2.0-33847795928 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/25081 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33847795928&origin=inward | en_US |
| dc.subject | Medicine | en_US |
| dc.title | Release of granzymes and chemokines in Thai patients with leptospirosis | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33847795928&origin=inward | en_US |