Publication: Episomal vector reprogramming of human umbilical cord blood natural killer cells to an induced pluripotent stem cell line MUSIi013-A
| dc.contributor.author | Phatchanat Klaihmon | en_US |
| dc.contributor.author | Sudjit Luanpitpong | en_US |
| dc.contributor.author | Chanchao Lorthongpanich | en_US |
| dc.contributor.author | Chuti Laowtammathron | en_US |
| dc.contributor.author | Supaporn Waeteekul | en_US |
| dc.contributor.author | Papussorn Terbto | en_US |
| dc.contributor.author | Surapol Issaragrisil | en_US |
| dc.contributor.other | Siriraj Hospital | en_US |
| dc.date.accessioned | 2022-08-04T08:07:10Z | |
| dc.date.available | 2022-08-04T08:07:10Z | |
| dc.date.issued | 2021-08-01 | en_US |
| dc.description.abstract | Natural killer (NK) cells were isolated from human umbilical cord blood from a healthy newborn and reprogrammed by episomal vectors carrying reprograming factors L-MYC, LIN28, OCT4, SOX2, KLF4, EBNA-1, and shRNA against p53 delivered using nucleofection. The obtained MUSIi013-A human induced pluripotent stem cell (iPSC) line highly expressed pluripotency markers, had the capacity to differentiate into derivatives of the three germ layers, while retained a normal karyotype. This cell line may be a useful tool to study epigenic memory that may predispose hiPSCs to enhanced NK differentiation. | en_US |
| dc.identifier.citation | Stem Cell Research. Vol.55, (2021) | en_US |
| dc.identifier.doi | 10.1016/j.scr.2021.102472 | en_US |
| dc.identifier.issn | 18767753 | en_US |
| dc.identifier.issn | 18735061 | en_US |
| dc.identifier.other | 2-s2.0-85111051321 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/76092 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85111051321&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.title | Episomal vector reprogramming of human umbilical cord blood natural killer cells to an induced pluripotent stem cell line MUSIi013-A | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85111051321&origin=inward | en_US |