Publication:
Short report: Dihydroartemisinin - Piperaquine rescue treatment of multidrug-resistant Plasmodium falciparum malaria in pregnancy: A preliminary report

dc.contributor.authorMarcus J. Rijkenen_US
dc.contributor.authorRose McGreadyen_US
dc.contributor.authorMachteld E. Boelen_US
dc.contributor.authorMarion Barendsen_US
dc.contributor.authorStephane Prouxen_US
dc.contributor.authorMupawjay Pimanpanaraken_US
dc.contributor.authorPratap Singhasivanonen_US
dc.contributor.authorFrançois Nostenen_US
dc.contributor.otherShoklo Malaria Research Uniten_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-07-12T02:31:07Z
dc.date.available2018-07-12T02:31:07Z
dc.date.issued2008-04-01en_US
dc.description.abstractDihydroartemisinin-piperaquine (DHA-PPQ) is a promising new artemisinin combination treatment. There are no published data on the intentional use of the drug in pregnancy. Between June 2006 and January 2007, 50 Karen pregnant women with recurrent P. falciparum infections, despite 7-day treatments with quinine or artesunate (+/-clindamycin) or both, were treated with DHA-PPQ. This rescue treatment was effective and well tolerated and there was no evidence of toxicity for the mothers or the fetus. The PCR adjusted cure rate by Kaplan Meier analysis at day 63 was 92.2% (95% CI: 76.9-97.4). Copyright © 2008 by The American Society of Tropical Medicine and Hygiene.en_US
dc.identifier.citationAmerican Journal of Tropical Medicine and Hygiene. Vol.78, No.4 (2008), 543-545en_US
dc.identifier.issn00029637en_US
dc.identifier.other2-s2.0-45349085248en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/19347
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=45349085248&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleShort report: Dihydroartemisinin - Piperaquine rescue treatment of multidrug-resistant Plasmodium falciparum malaria in pregnancy: A preliminary reporten_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=45349085248&origin=inwarden_US

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